Shigella flexneri, the causative agent of dysentery (orange), establishes contact with a human host cell (blue). The bar corresponds to a micrometer or a thousandth millimeter, respectively. Credit: Volker Brinkmann, Diane Schad, and Michael Kolbe
You can clearly see the two membranes (orange) enclosing the cell interior (blue) and the needles protruding to the outside (orange, marked in blue). The bar corresponds to a micrometer or a thousandth millimeter, respectively. Credit: Ulrike Abu Abed, Diane Schad, and Michael Kolbe
The change of the three-dimensional structure of the proteins during the needle assembly was analyzed by X-ray structural experiments at BESSY in Berlin and ESRF in Grenoble and NMR-spectroscopic experiments based on radio waves at the Max Planck Institute for Biophysical Chemistry. The scientists compared the three-dimensional structure of the needle protein before and after the needle assembly.Original paper:
Michael Kolbe | EurekAlert!
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