One of the biggest challenges has been to create multi-layer tissue structures designed to enable the diffusion of nutrients for surrounding cells in a similar manner to natural tissue.
This task is now being tackled by a consortium of 16 European partners from industry and the research community under the leadership of the Fraunhofer Institute for Laser Technology ILT.
On November 23rd and 24th, 2011, Fraunhofer ILT held the kick-off meeting for the project ArtiVasc 3D, which will receive 7.8 million euros of funding from the European Commission under the Seventh Framework Programme. A team of engineers, scientists and medical experts has announced its goal to develop a new process of engineering a vascularized scaffold for artificial tissue, in other words to provide the tissue with a blood supply similar to that of natural arteries. Using current technologies, skin grafts that do not require vascularization cannot be grown beyond a surface area of 1 cm² and a thickness of 1-2 mm. For larger and thicker areas of tissue, vascularization is necessary.
Over the next four years, the consortium will combine different technologies from the fields of additive manufacturing and biofunctionalization to develop a process capable of engineering blood vessels in an artificial scaffold system. These vascularized scaffolds will be populated with autologous cells in order to enable the formation of vascularized fatty tissue and, ultimately, artificial skin. This artificial skin will be used as an in vitro test system – for example to reduce the number of animal experiments – and employed directly in skin grafts.Your contacts at Fraunhofer ILT
Axel Bauer | Fraunhofer-Institut
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Physicists at the University of Bonn have managed to create optical hollows and more complex patterns into which the light of a Bose-Einstein condensate flows. The creation of such highly low-loss structures for light is a prerequisite for complex light circuits, such as for quantum information processing for a new generation of computers. The researchers are now presenting their results in the journal Nature Photonics.
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For the first time, scientists have shown that circular RNA is linked to brain function. When a RNA molecule called Cdr1as was deleted from the genome of mice, the animals had problems filtering out unnecessary information – like patients suffering from neuropsychiatric disorders.
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An experimental small satellite has successfully collected and delivered data on a key measurement for predicting changes in Earth's climate.
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A study led by scientists of the Max Planck Institute for the Structure and Dynamics of Matter (MPSD) at the Center for Free-Electron Laser Science in Hamburg presents evidence of the coexistence of superconductivity and “charge-density-waves” in compounds of the poorly-studied family of bismuthates. This observation opens up new perspectives for a deeper understanding of the phenomenon of high-temperature superconductivity, a topic which is at the core of condensed matter research since more than 30 years. The paper by Nicoletti et al has been published in the PNAS.
Since the beginning of the 20th century, superconductivity had been observed in some metals at temperatures only a few degrees above the absolute zero (minus...
Researchers from the University of Miami (UM) Rosenstiel School of Marine and Atmospheric Science, the Italian Space Agency (ASI), and the Instituto Geofisico--Escuela Politecnica Nacional (IGEPN) of Ecuador, showed an increasing volcanic danger on Cotopaxi in Ecuador using a powerful technique known as Interferometric Synthetic Aperture Radar (InSAR).
The Andes region in which Cotopaxi volcano is located is known to contain some of the world's most serious volcanic hazard. A mid- to large-size eruption has...
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