The ancient genetic record reveals the negative changes in oral bacteria brought about by the dietary shifts as humans became farmers, and later with the introduction of food manufacturing in the Industrial Revolution.
Photo by Alan Cooper, University of Adelaide
Teeth of late Iron Age/Roman woman showing large dental calculus deposit, from Cambridge area, UK.
An international team, led by the University of Adelaide’s Centre for Ancient DNA (ACAD) where the research was performed, has published the results in Nature Genetics today. Other team members include the Department of Archaeology at the University of Aberdeen and the Wellcome Trust Sanger Institute in Cambridge (UK).
“This is the first record of how our evolution over the last 7500 years has impacted the bacteria we carry with us, and the important health consequences,” says study leader Professor Alan Cooper, ACAD Director.
“Oral bacteria in modern man are markedly less diverse than historic populations and this is thought to contribute to chronic oral and other disease in post-industrial lifestyles.”
The researchers extracted DNA from tartar (calcified dental plaque) from 34 prehistoric northern European human skeletons, and traced changes in the nature of oral bacteria from the last hunter-gatherers, through the first farmers to the Bronze Age and Medieval times.
“Dental plaque represents the only easily accessible source of preserved human bacteria,” says lead author Dr Christina Adler, who conducted the research while a PhD student at the University of Adelaide, now at the University of Sydney.
“Genetic analysis of plaque can create a powerful new record of dietary impacts, health changes and oral pathogen genomic evolution, deep into the past.”
Professor Cooper says: “The composition of oral bacteria changed markedly with the introduction of farming, and again around 150 years ago. With the introduction of processed sugar and flour in the Industrial Revolution, we can see a dramatically decreased diversity in our oral bacteria, allowing domination by caries-causing strains. The modern mouth basically exists in a permanent disease state.”
Professor Cooper has been working on the project with archaeologist and co-Leader Professor Keith Dobney, now at the University of Aberdeen, for the past 17 years. Professor Dobney says: “I had shown tartar deposits commonly found on ancient teeth were dense masses of solid calcified bacteria and food, but couldn’t identify the species of bacteria. Ancient DNA was the obvious answer.”
However, the team was not able to sufficiently control background levels of bacterial contamination until 2007 when ACAD’s ultra-clean laboratories and strict decontamination and authentication protocols became available. The research team is now expanding its studies through time, and around the world, including other species such as Neandertals.Photo caption:
Robyn Mills | Newswise
27.03.2015 | Oak Ridge National Laboratory
How did the chicken cross the sea?
27.03.2015 | Michigan State University
In an experiment at the Department of Energy's SLAC National Accelerator Laboratory, scientists precisely measured the temperature and structure of aluminum as...
The IPH presents a solution at HANNOVER MESSE 2015 to make ship traffic more reliable while decreasing the maintenance costs at the same time. In cooperation with project partners, the research institute from Hannover, Germany, has developed a sensor system which continuously monitors the condition of the marine gearbox, thus preventing breakdowns. Special feature: the monitoring system works wirelessly and energy-autonomously. The required electrical power is generated where it is needed – directly at the sensor.
As well as cars need to be certified regularly (in Germany by the TÜV – Technical Inspection Association), ships need to be inspected – if the powertrain stops...
When an earthquake hits, the faster first responders can get to an impacted area, the more likely infrastructure--and lives--can be saved.
The Atlantic overturning is one of Earth’s most important heat transport systems, pumping warm water northwards and cold water southwards. Also known as the Gulf Stream system, it is responsible for the mild climate in northwestern Europe.
Scientists now found evidence for a slowdown of the overturning – multiple lines of observation suggest that in recent decades, the current system has been...
Because they are regularly subjected to heavy vehicle traffic, emissions, moisture and salt, above- and underground parking garages, as well as bridges, frequently experience large areas of corrosion. Most inspection systems to date have only been capable of inspecting smaller surface areas.
From April 13 to April 17 at the Hannover Messe (hall 2, exhibit booth C16), engineers from the Fraunhofer Institute for Nondestructive Testing IZFP will be...
25.03.2015 | Event News
19.03.2015 | Event News
17.03.2015 | Event News
27.03.2015 | Agricultural and Forestry Science
27.03.2015 | Materials Sciences
27.03.2015 | Ecology, The Environment and Conservation