In other words, a biological specimen determined by traditional DNA testing to be 100,000 years old may actually be 200,000 to 600,000 years old, researchers suggest in a new report in Trends in Genetics, a professional journal.
The findings raise doubts about the accuracy of many evolutionary rates based on conventional types of genetic analysis.
“Some earlier work based on small amounts of DNA indicated this same problem, but now we have more conclusive evidence based on the study of almost an entire mitochondrial genome,” said Dee Denver, an evolutionary biologist with the Center for Genome Research and Biocomputing at Oregon State University.
“The observations in this report appear to be fundamental and should extend to most animal species,” he added. “We believe that traditional DNA dating techniques are fundamentally flawed, and that the rates of evolution are in fact much faster than conventional technologies have led us to believe.”
The findings, researchers say, are primarily a challenge to the techniques used to determine the age of a sample by genetic analysis alone, rather than by other observations about fossils. In particular, they may force a widespread re-examination of determinations about when one species split off from another, if that determination was based largely on genetic evidence.
For years, researchers have been using their understanding of the rates of genetic mutations in cells to help date ancient biological samples, and in what’s called “phylogenetic comparison,” used that information along with fossil evidence to determine the dates of fossils and the history of evolution. The rates of molecular evolution “underpin much of modern evolutionary biology,” the researchers noted in their report.
“For the genetic analysis to be accurate, however, you must have the right molecular clock rate,” Denver said. “We now think that many genetic changes were happening that conventional DNA analysis did not capture. They were fairly easy to use and apply but also too indirect, and inaccurate as a result.”
This conclusion, researchers said, was forced by the study of many penguin bones that were well preserved by sub-freezing temperatures in Antarctica. These penguins live in massive rookeries, have inhabited the same areas for thousands of years, and it was comparatively simple to identify bones of different ages just by digging deeper in areas where they died and their bones piled up.
For their study, the scientists used a range of mitochondrial DNA found in bones ranging from 250 years to about 44,000 years old.
“In a temperate zone when an animal dies and falls to the ground, their DNA might degrade within a year,” Denver said. “In Antarctica the same remains are well-preserved for tens of thousands of years. It’s a remarkable scientific resource.”
A precise study of this ancient DNA was compared to the known ages of the bones, and produced results that were far different than conventional analysis would have suggested. Researchers also determined that different types of DNA sequences changed at different rates.
Aside from raising doubts about the accuracy of many specimens dated with conventional approaches, the study may give researchers tools to improve their future dating estimates, Denver said.
Collaborators on the research included scientists from OSU, Griffith University in Australia, the University of Auckland in New Zealand, Massey University in New Zealand, University of North Carolina in Wilmington, the Scripps Research Institute, and Universita’ di Pisa in Italy.
The studies were supported by the National Science Foundation, National Geographic Society, and other agencies.
About the OSU College of Science: As one of the largest academic units at OSU, the College of Science has 14 departments and programs, 13 pre-professional programs, and provides the basic science courses essential to the education of every OSU student. Its faculty are international leaders in scientific research.
Dee Denver | EurekAlert!
When fat cells change their colour
28.10.2016 | Albert-Ludwigs-Universität Freiburg im Breisgau
Aquaculture: Clear Water Thanks to Cork
28.10.2016 | Technologie Lizenz-Büro (TLB) der Baden-Württembergischen Hochschulen GmbH
Physicists from the University of Würzburg have designed a light source that emits photon pairs. Two-photon sources are particularly well suited for tap-proof data encryption. The experiment's key ingredients: a semiconductor crystal and some sticky tape.
So-called monolayers are at the heart of the research activities. These "super materials" (as the prestigious science magazine "Nature" puts it) have been...
Ultrafast lasers have introduced new possibilities in engraving ultrafine structures, and scientists are now also investigating how to use them to etch microstructures into thin glass. There are possible applications in analytics (lab on a chip) and especially in electronics and the consumer sector, where great interest has been shown.
This new method was born of a surprising phenomenon: irradiating glass in a particular way with an ultrafast laser has the effect of making the glass up to a...
Terahertz excitation of selected crystal vibrations leads to an effective magnetic field that drives coherent spin motion
Controlling functional properties by light is one of the grand goals in modern condensed matter physics and materials science. A new study now demonstrates how...
Researchers from the Institute for Quantum Computing (IQC) at the University of Waterloo led the development of a new extensible wiring technique capable of controlling superconducting quantum bits, representing a significant step towards to the realization of a scalable quantum computer.
"The quantum socket is a wiring method that uses three-dimensional wires based on spring-loaded pins to address individual qubits," said Jeremy Béjanin, a PhD...
In a paper in Scientific Reports, a research team at Worcester Polytechnic Institute describes a novel light-activated phenomenon that could become the basis for applications as diverse as microscopic robotic grippers and more efficient solar cells.
A research team at Worcester Polytechnic Institute (WPI) has developed a revolutionary, light-activated semiconductor nanocomposite material that can be used...
14.10.2016 | Event News
14.10.2016 | Event News
12.10.2016 | Event News
28.10.2016 | Power and Electrical Engineering
28.10.2016 | Physics and Astronomy
28.10.2016 | Life Sciences