Peixuan Guo and colleagues point out that DNA, the double-stranded genetic blueprint of life, and RNA, its single-stranded cousin, share common chemical features that can serve as building blocks for making nanostructures and nanodevices. In some ways, RNA even has advantages over DNA. The field of DNA nanotechnology is already well-established, they note.
The decade-old field of RNA nanotechnology shows great promise, with potential applications in the treatment of cancer, viral, and genetic diseases. However, the chemical instability of RNA and its tendency to breakdown in the presence of enzymes have slowed progress in the field.
The scientists describe development of a highly stable RNA nanoparticle. They tested its ability to power the nano-sized biological motor of a certain bacteriophage — a virus that infects bacteria — that operates using molecules of RNA. The modified RNA showed excellent biological activity similar, even in the presence of high concentrations of enzymes that normally breakdown RNA. The finding show that "it is practical to produce RNase (an enzyme that degrades RNA) resistant, biologically active, and stable RNA for application in nanotechnology," the article notes.
The authors acknowledged funding from the National Institutes of Health.ARTICLE FOR IMMEDIATE RELEASE
Michael Bernstein | EurekAlert!
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The Institute of Semiconductor Technology and the Institute of Physical and Theoretical Chemistry, both members of the Laboratory for Emerging Nanometrology (LENA), at Technische Universität Braunschweig are partners in a new European research project entitled ChipScope, which aims to develop a completely new and extremely small optical microscope capable of observing the interior of living cells in real time. A consortium of 7 partners from 5 countries will tackle this issue with very ambitious objectives during a four-year research program.
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Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.
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Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.
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Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...
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