Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

New Abbott Technology Offers Rapid Alternative to Culture for Microbial Detection

23.11.2009
Research presented today at the Association for Molecular Pathology (AMP) annual meeting indicates that a new molecular diagnostic technology from Abbott identified more microbes and delivered more rapid results than traditional culture testing methods.

In a poster presented at the AMP meeting, Donna Wolk, Ph.D., division chief, microbiology, University of Arizona, compared the performance of Abbott's Ibis T-5000 system’s bacterial candida and antimicrobial resistance assay (BCA) with traditional culture testing for 221 blood culture broth samples from patients infected with gram-positive and gram-negative aerobes, anaerobes and yeast. The T-5000 system is intended for research use only, and is not approved in the United States for clinical applications.

Compared to culture, the BCA assay identified 22 more microbial isolates of which 19 were pathogenic species. The BCA assay correctly identified 217 blood culture results. Further, the BCA assay identified significantly more pathogenic bacteria and yeast than routine subculture, and BCA results were reported in seven hours while the individual subculture results were not available for 48 to 72 hours.

“In our research, the assay showed it can identify microbes that can’t be detected by routine methods and has potential to streamline rapid microbial identification and antibiotic resistance testing into one multiplex method,” Wolk said.

Currently intended for research use only, the T-5000 is the only high-throughput technology that simultaneously enables broad identification, detailed genotyping and characterization, and recognition of emerging organisms. The system is based on both PCR and mass spectrometry analysis for rapid and reliable detection of microbes.

About Abbott Molecular
Abbott Molecular (abbottmolecular.com) is an emerging leader in molecular diagnostics - the analysis of DNA, RNA, and proteins at the molecular level. Abbott Molecular's instruments and reagents detect pathogens and subtle, but key changes in patients' genes and chromosomes, which permit earlier diagnoses, the selection of appropriate therapies and improved monitoring of disease progression.
About Abbott
Abbott is a global, broad-based health care company devoted to the discovery, development, manufacture and marketing of pharmaceuticals and medical products, including nutritionals, devices and diagnostics. The company employs more than 72,000 people and markets its products in more than 130 countries.

Don Braakman | Newswise Science News
Further information:
http://www.abbott.com

More articles from Life Sciences:

nachricht Topologische Quantenchemie
21.07.2017 | Max-Planck-Institut für Chemische Physik fester Stoffe

nachricht Topological Quantum Chemistry
21.07.2017 | Max-Planck-Institut für Chemische Physik fester Stoffe

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Manipulating Electron Spins Without Loss of Information

Physicists have developed a new technique that uses electrical voltages to control the electron spin on a chip. The newly-developed method provides protection from spin decay, meaning that the contained information can be maintained and transmitted over comparatively large distances, as has been demonstrated by a team from the University of Basel’s Department of Physics and the Swiss Nanoscience Institute. The results have been published in Physical Review X.

For several years, researchers have been trying to use the spin of an electron to store and transmit information. The spin of each electron is always coupled...

Im Focus: The proton precisely weighted

What is the mass of a proton? Scientists from Germany and Japan successfully did an important step towards the most exact knowledge of this fundamental constant. By means of precision measurements on a single proton, they could improve the precision by a factor of three and also correct the existing value.

To determine the mass of a single proton still more accurate – a group of physicists led by Klaus Blaum and Sven Sturm of the Max Planck Institute for Nuclear...

Im Focus: On the way to a biological alternative

A bacterial enzyme enables reactions that open up alternatives to key industrial chemical processes

The research team of Prof. Dr. Oliver Einsle at the University of Freiburg's Institute of Biochemistry has long been exploring the functioning of nitrogenase....

Im Focus: The 1 trillion tonne iceberg

Larsen C Ice Shelf rift finally breaks through

A one trillion tonne iceberg - one of the biggest ever recorded -- has calved away from the Larsen C Ice Shelf in Antarctica, after a rift in the ice,...

Im Focus: Laser-cooled ions contribute to better understanding of friction

Physics supports biology: Researchers from PTB have developed a model system to investigate friction phenomena with atomic precision

Friction: what you want from car brakes, otherwise rather a nuisance. In any case, it is useful to know as precisely as possible how friction phenomena arise –...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Closing the Sustainability Circle: Protection of Food with Biobased Materials

21.07.2017 | Event News

»We are bringing Additive Manufacturing to SMEs«

19.07.2017 | Event News

The technology with a feel for feelings

12.07.2017 | Event News

 
Latest News

NASA looks to solar eclipse to help understand Earth's energy system

21.07.2017 | Earth Sciences

Stanford researchers develop a new type of soft, growing robot

21.07.2017 | Power and Electrical Engineering

Vortex photons from electrons in circular motion

21.07.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>