Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Seeing a bionic eye on medicine's horizon

23.03.2010
Tel Aviv University pioneers research for new retinal implant technology

Television's Six Million Dollar Man foresaw a future when man and machine would become one. New research at Tel Aviv University is making this futuristic "vision" of bionics a reality.

Prof. Yael Hanein of Tel Aviv University's School of Electrical Engineering has foundational research that may give sight to blind eyes, merging retinal nerves with electrodes to stimulate cell growth. Successful so far in animal models, this research may one day lay the groundwork for retinal implants in people.

But that's a way off, she says. Until then, her half-human, half-machine invention can be used by drug developers investigating new compounds or formulations to treat delicate nerve tissues in the brain. Prof. Hanein's research group published its work recently in the journal Nanotechnology.

Implanting the idea

"We're working to interface man-made technology with neurons," says Prof. Hanein. "It can be helpful in in vitro and in in vivo applications, and provides an understanding of how neurons work so we can build better devices and drugs," she says.

She's developed a spaghetti like mass of nano-sized (one-millionth of a millimetre) carbon tubes, and using an electric current has managed to coax living neurons from the brains of rats to grow on this man-made structure. The growth of living cells on the nano substrate is a very complicated process, she says, but they adhere well to the structure, fusing with the synthetic electrical and physical interface. Using the new technology developed in Prof. Hanein's laboratory, her graduate student Mark Shein has been observing how neurons communicate and work together.

"We are attempting to answer very basic questions in science," Prof. Hanein explains. "Neurons migrate and assemble themselves, and using approaches we've developed, we are now able to 'listen' to the way the neurons fire and communicate with one another using electrical impulses. Listening to neurons 'talking' allows us to answer the most basic questions of how groups of nerves work together. If we can investigate functional neuronal networks in the lab, we can study what can't be seen or heard in the complete brain, where there are too many signals in one place."

Paging Steve Austin

One application of Prof. Hanein's research is a new approach to aid people with retinal degeneration diseases. There are several retinal diseases which are incurable, such as retinitis pigmentosa, and some researchers are investigating a prosthetic device which could replace the damaged cells.

"Neurons like to form good links with our special nanotechnology, and we're now investigating applications for retinal implants," says Prof. Hanein. "Our retinal implant attempts to replace activity in places of the damaged cells, and in the case of retinal diseases, the damaged photoreceptors."

The team's major breakthrough is creating these man-made living "devices" on a flexible nano-material suited for the small area in the eye where new neuron connection growth would be needed. This is the first step in a long clinical process that may lead to improved vision ¯ and perhaps, one day, a real-life six million dollar man.

American Friends of Tel Aviv University (www.aftau.org) supports Israel's leading and most comprehensive center of higher learning. In independent rankings, TAU's innovations and discoveries are cited more often by the global scientific community than all but 20 other universities worldwide.

Internationally recognized for the scope and groundbreaking nature of its research programs, Tel Aviv University consistently produces work with profound implications for the future.

George Hunka | EurekAlert!
Further information:
http://www.aftau.org

More articles from Life Sciences:

nachricht Cancer diagnosis: no more needles?
25.05.2018 | Christian-Albrechts-Universität zu Kiel

nachricht Less is more? Gene switch for healthy aging found
25.05.2018 | Leibniz-Institut für Alternsforschung - Fritz-Lipmann-Institut e.V. (FLI)

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Powerful IT security for the car of the future – research alliance develops new approaches

The more electronics steer, accelerate and brake cars, the more important it is to protect them against cyber-attacks. That is why 15 partners from industry and academia will work together over the next three years on new approaches to IT security in self-driving cars. The joint project goes by the name Security For Connected, Autonomous Cars (SecForCARs) and has funding of €7.2 million from the German Federal Ministry of Education and Research. Infineon is leading the project.

Vehicles already offer diverse communication interfaces and more and more automated functions, such as distance and lane-keeping assist systems. At the same...

Im Focus: Molecular switch will facilitate the development of pioneering electro-optical devices

A research team led by physicists at the Technical University of Munich (TUM) has developed molecular nanoswitches that can be toggled between two structurally different states using an applied voltage. They can serve as the basis for a pioneering class of devices that could replace silicon-based components with organic molecules.

The development of new electronic technologies drives the incessant reduction of functional component sizes. In the context of an international collaborative...

Im Focus: LZH showcases laser material processing of tomorrow at the LASYS 2018

At the LASYS 2018, from June 5th to 7th, the Laser Zentrum Hannover e.V. (LZH) will be showcasing processes for the laser material processing of tomorrow in hall 4 at stand 4E75. With blown bomb shells the LZH will present first results of a research project on civil security.

At this year's LASYS, the LZH will exhibit light-based processes such as cutting, welding, ablation and structuring as well as additive manufacturing for...

Im Focus: Self-illuminating pixels for a new display generation

There are videos on the internet that can make one marvel at technology. For example, a smartphone is casually bent around the arm or a thin-film display is rolled in all directions and with almost every diameter. From the user's point of view, this looks fantastic. From a professional point of view, however, the question arises: Is that already possible?

At Display Week 2018, scientists from the Fraunhofer Institute for Applied Polymer Research IAP will be demonstrating today’s technological possibilities and...

Im Focus: Explanation for puzzling quantum oscillations has been found

So-called quantum many-body scars allow quantum systems to stay out of equilibrium much longer, explaining experiment | Study published in Nature Physics

Recently, researchers from Harvard and MIT succeeded in trapping a record 53 atoms and individually controlling their quantum state, realizing what is called a...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

In focus: Climate adapted plants

25.05.2018 | Event News

Save the date: Forum European Neuroscience – 07-11 July 2018 in Berlin, Germany

02.05.2018 | Event News

Invitation to the upcoming "Current Topics in Bioinformatics: Big Data in Genomics and Medicine"

13.04.2018 | Event News

 
Latest News

In focus: Climate adapted plants

25.05.2018 | Event News

Flow probes from the 3D printer

25.05.2018 | Machine Engineering

Less is more? Gene switch for healthy aging found

25.05.2018 | Life Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>