The LIA group has submitted a patent application for the design of this logical DNA sensor. These sensors are able to represent logical implications (or IF-THEN rules), like, for example, IF symptom 1 and symptom 2 are present, THEN the disease is A, or IF the disease is B, THEN symptoms 2 and 3 must be present.
The sensors are able to use these logical rules to autonomously run logical inference processes on the genetic input signals and reach accurate diagnoses.
Using these intelligent DNA sensors as basic building blocks, the aim is to develop in vitro systems capable of autonomously detecting a set of input symptoms and output a diagnosis or release the right drug.
These biological sensors (built with DNA to process DNA) are considered bionanotechnological devices and are part of a discipline called DNA computing or biomolecular computing. This discipline aims to build and program devices manufactured with biomolecules, such as, for example, DNA strands to process information likewise encoded in other biomolecules.
In short, there is a need to develop and manufacture biological sensors capable of precisely detecting complex combinations of genetic signals and autonomously issuing the respective diagnoses.
The bionanotechnological devices developed by the UPM's LIA group at the Facultad de Informática are a response to this need.
Eduardo Martínez | alfa
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The Institute of Semiconductor Technology and the Institute of Physical and Theoretical Chemistry, both members of the Laboratory for Emerging Nanometrology (LENA), at Technische Universität Braunschweig are partners in a new European research project entitled ChipScope, which aims to develop a completely new and extremely small optical microscope capable of observing the interior of living cells in real time. A consortium of 7 partners from 5 countries will tackle this issue with very ambitious objectives during a four-year research program.
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Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...
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