Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

200,000 rice mutants available worldwide for scientific investigation

06.03.2009
Scientists across the world are building an extensive repository of genetically modified rice plants in the hope of understanding the function of the approximately 57,000 genes that make up the genome of Oryza sativa.

The International Rice Functional Genomics Consortium recently announced the public availability of more than 200,000 rice mutant lines, which represent mutations in about half of the known functional genes mapped for rice to date. *

Researchers have estimated the number of different rice mutants needed to have a mutant for every gene as somewhere between 180,698 and 460,000. Two hundred thousand rice mutants are now available and have been mapped by the insertion of what are known as flanking sequence tags – small pieces of DNA or molecular tags that integrate into the rice genome. This approach is useful because it allows scientists to link a physical location on the genome to a specific gene and its visible feature or phenotype.

Arjun Krishnan, first author on the paper and a graduate student in Andy Pereira's laboratory at the Virginia Bioinformatics Institute, stated: "Bioinformatics is making it possible to visualize the vast amounts of sequence information available to researchers. The resources described in this paper, which are the combined output of many leading international rice research laboratories, mean that researchers can see and explore on their computers the precise positions of mutations in the rice genome sequence, for each rice mutant plant. About 50 percent of the protein-coding genes have knockout mutations, which probably abolish their expression and can provide valuable information on the genes by virtue of their loss of function. This is a significant milestone for the project and the availability of these rice plants represents a powerful resource for the rice genomics community."

More than 2 million rice mutants were generated in this project and the diversity of the available plants suits many of the experimental objectives of researchers looking at rice and other commercially important grasses. Mapping of the remaining genes from this population will be required to complete the resource. Many of them will be smaller genes less amenable to mutation that will pose significant challenges for researchers as they continue their work.

Dr. Andy Pereira, Professor at the Virginia Bioinformatics Institute, stated: "The Oryza sativa genome was sequenced in 2002 and researchers have come a long way since. Advances in technologies such as high-throughput sequencing and RNA interference gene silencing methods should help to accelerate the process of identifying the functions of the remaining genes in the rice genome." He added: "The availability of the rice mutant resource is already helping researchers in their quest to gain insights into the biology of this commercially important crop. These efforts are critical to understand gene function and, ultimately, the many biological processes that take place in rice and other grasses, including maize and wheat, which collectively produce our staple food."

* Krishnan A, Guiderdoni E, An G, Hsing YI, Han CD, Lee MC, Yu SM, Upadhyaya N, Ramachandran S, Zhang Q, Sundaresan V, Hirochika H, Leung H, Pereira A (2009) Plant Physiology 149(1): 165-170

Barry Whyte | EurekAlert!
Further information:
http://www.vbi.vt.edu

More articles from Life Sciences:

nachricht Could this protein protect people against coronary artery disease?
17.11.2017 | University of North Carolina Health Care

nachricht Microbial resident enables beetles to feed on a leafy diet
17.11.2017 | Max-Planck-Institut für chemische Ökologie

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: A “cosmic snake” reveals the structure of remote galaxies

The formation of stars in distant galaxies is still largely unexplored. For the first time, astron-omers at the University of Geneva have now been able to closely observe a star system six billion light-years away. In doing so, they are confirming earlier simulations made by the University of Zurich. One special effect is made possible by the multiple reflections of images that run through the cosmos like a snake.

Today, astronomers have a pretty accurate idea of how stars were formed in the recent cosmic past. But do these laws also apply to older galaxies? For around a...

Im Focus: Visual intelligence is not the same as IQ

Just because someone is smart and well-motivated doesn't mean he or she can learn the visual skills needed to excel at tasks like matching fingerprints, interpreting medical X-rays, keeping track of aircraft on radar displays or forensic face matching.

That is the implication of a new study which shows for the first time that there is a broad range of differences in people's visual ability and that these...

Im Focus: Novel Nano-CT device creates high-resolution 3D-X-rays of tiny velvet worm legs

Computer Tomography (CT) is a standard procedure in hospitals, but so far, the technology has not been suitable for imaging extremely small objects. In PNAS, a team from the Technical University of Munich (TUM) describes a Nano-CT device that creates three-dimensional x-ray images at resolutions up to 100 nanometers. The first test application: Together with colleagues from the University of Kassel and Helmholtz-Zentrum Geesthacht the researchers analyzed the locomotory system of a velvet worm.

During a CT analysis, the object under investigation is x-rayed and a detector measures the respective amount of radiation absorbed from various angles....

Im Focus: Researchers Develop Data Bus for Quantum Computer

The quantum world is fragile; error correction codes are needed to protect the information stored in a quantum object from the deteriorating effects of noise. Quantum physicists in Innsbruck have developed a protocol to pass quantum information between differently encoded building blocks of a future quantum computer, such as processors and memories. Scientists may use this protocol in the future to build a data bus for quantum computers. The researchers have published their work in the journal Nature Communications.

Future quantum computers will be able to solve problems where conventional computers fail today. We are still far away from any large-scale implementation,...

Im Focus: Wrinkles give heat a jolt in pillared graphene

Rice University researchers test 3-D carbon nanostructures' thermal transport abilities

Pillared graphene would transfer heat better if the theoretical material had a few asymmetric junctions that caused wrinkles, according to Rice University...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Ecology Across Borders: International conference brings together 1,500 ecologists

15.11.2017 | Event News

Road into laboratory: Users discuss biaxial fatigue-testing for car and truck wheel

15.11.2017 | Event News

#Berlin5GWeek: The right network for Industry 4.0

30.10.2017 | Event News

 
Latest News

NASA detects solar flare pulses at Sun and Earth

17.11.2017 | Physics and Astronomy

NIST scientists discover how to switch liver cancer cell growth from 2-D to 3-D structures

17.11.2017 | Health and Medicine

The importance of biodiversity in forests could increase due to climate change

17.11.2017 | Studies and Analyses

VideoLinks
B2B-VideoLinks
More VideoLinks >>>