Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

200,000 rice mutants available worldwide for scientific investigation

06.03.2009
Scientists across the world are building an extensive repository of genetically modified rice plants in the hope of understanding the function of the approximately 57,000 genes that make up the genome of Oryza sativa.

The International Rice Functional Genomics Consortium recently announced the public availability of more than 200,000 rice mutant lines, which represent mutations in about half of the known functional genes mapped for rice to date. *

Researchers have estimated the number of different rice mutants needed to have a mutant for every gene as somewhere between 180,698 and 460,000. Two hundred thousand rice mutants are now available and have been mapped by the insertion of what are known as flanking sequence tags – small pieces of DNA or molecular tags that integrate into the rice genome. This approach is useful because it allows scientists to link a physical location on the genome to a specific gene and its visible feature or phenotype.

Arjun Krishnan, first author on the paper and a graduate student in Andy Pereira's laboratory at the Virginia Bioinformatics Institute, stated: "Bioinformatics is making it possible to visualize the vast amounts of sequence information available to researchers. The resources described in this paper, which are the combined output of many leading international rice research laboratories, mean that researchers can see and explore on their computers the precise positions of mutations in the rice genome sequence, for each rice mutant plant. About 50 percent of the protein-coding genes have knockout mutations, which probably abolish their expression and can provide valuable information on the genes by virtue of their loss of function. This is a significant milestone for the project and the availability of these rice plants represents a powerful resource for the rice genomics community."

More than 2 million rice mutants were generated in this project and the diversity of the available plants suits many of the experimental objectives of researchers looking at rice and other commercially important grasses. Mapping of the remaining genes from this population will be required to complete the resource. Many of them will be smaller genes less amenable to mutation that will pose significant challenges for researchers as they continue their work.

Dr. Andy Pereira, Professor at the Virginia Bioinformatics Institute, stated: "The Oryza sativa genome was sequenced in 2002 and researchers have come a long way since. Advances in technologies such as high-throughput sequencing and RNA interference gene silencing methods should help to accelerate the process of identifying the functions of the remaining genes in the rice genome." He added: "The availability of the rice mutant resource is already helping researchers in their quest to gain insights into the biology of this commercially important crop. These efforts are critical to understand gene function and, ultimately, the many biological processes that take place in rice and other grasses, including maize and wheat, which collectively produce our staple food."

* Krishnan A, Guiderdoni E, An G, Hsing YI, Han CD, Lee MC, Yu SM, Upadhyaya N, Ramachandran S, Zhang Q, Sundaresan V, Hirochika H, Leung H, Pereira A (2009) Plant Physiology 149(1): 165-170

Barry Whyte | EurekAlert!
Further information:
http://www.vbi.vt.edu

More articles from Life Sciences:

nachricht Topologische Quantenchemie
21.07.2017 | Max-Planck-Institut für Chemische Physik fester Stoffe

nachricht Topological Quantum Chemistry
21.07.2017 | Max-Planck-Institut für Chemische Physik fester Stoffe

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Manipulating Electron Spins Without Loss of Information

Physicists have developed a new technique that uses electrical voltages to control the electron spin on a chip. The newly-developed method provides protection from spin decay, meaning that the contained information can be maintained and transmitted over comparatively large distances, as has been demonstrated by a team from the University of Basel’s Department of Physics and the Swiss Nanoscience Institute. The results have been published in Physical Review X.

For several years, researchers have been trying to use the spin of an electron to store and transmit information. The spin of each electron is always coupled...

Im Focus: The proton precisely weighted

What is the mass of a proton? Scientists from Germany and Japan successfully did an important step towards the most exact knowledge of this fundamental constant. By means of precision measurements on a single proton, they could improve the precision by a factor of three and also correct the existing value.

To determine the mass of a single proton still more accurate – a group of physicists led by Klaus Blaum and Sven Sturm of the Max Planck Institute for Nuclear...

Im Focus: On the way to a biological alternative

A bacterial enzyme enables reactions that open up alternatives to key industrial chemical processes

The research team of Prof. Dr. Oliver Einsle at the University of Freiburg's Institute of Biochemistry has long been exploring the functioning of nitrogenase....

Im Focus: The 1 trillion tonne iceberg

Larsen C Ice Shelf rift finally breaks through

A one trillion tonne iceberg - one of the biggest ever recorded -- has calved away from the Larsen C Ice Shelf in Antarctica, after a rift in the ice,...

Im Focus: Laser-cooled ions contribute to better understanding of friction

Physics supports biology: Researchers from PTB have developed a model system to investigate friction phenomena with atomic precision

Friction: what you want from car brakes, otherwise rather a nuisance. In any case, it is useful to know as precisely as possible how friction phenomena arise –...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Closing the Sustainability Circle: Protection of Food with Biobased Materials

21.07.2017 | Event News

»We are bringing Additive Manufacturing to SMEs«

19.07.2017 | Event News

The technology with a feel for feelings

12.07.2017 | Event News

 
Latest News

NASA looks to solar eclipse to help understand Earth's energy system

21.07.2017 | Earth Sciences

Stanford researchers develop a new type of soft, growing robot

21.07.2017 | Power and Electrical Engineering

Vortex photons from electrons in circular motion

21.07.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>