National Insitute of Standards and Technology (NIST) scientists are taking their knowledge of mechanical tensile strength tests in metals and composites and applying it to medical research problems. Doctors long have known that babies born with congenital heart defects at higher altitudes have an increased risk of developing complications, such as pulmonary hypertension. Could there be some way to trick the arterial walls so that they wouldnt stiffen under increased blood pressure?
Working with the Childrens Hospital and University of Colorado Health Sciences Center in Denver, NIST researchers have used rat arteries--both normal and hypertensive--supplied by the university center and placed them in a mechanical stress tester. The tester holds a small disc-shaped sample of the arterial tissue that is slowly stretched by pumping a special liquid against the back of the disc. The pressure of the liquid causes a bubble to form on the front of the disc. The shape of the resulting bubble helps the researchers determine details about the tissues elasticity, strength, stiffness and other properties.
" Hypertensive tissue should be stiffer, so we will get less inflation with the same amount of pressure," says NIST researcher Elizabeth Drexler. "What we want to know is what it is in the artery that causes it to stiffen. Is it more collagen? Is it the smooth muscle cells? Perhaps we could give the muscle cell a signal not to produce more collagen." So far they have studied 20 rat arteries and plan to study 20 more, along with some calf arteries. A preliminary report that verifies their test method appears in the May/June issue of the NIST Journal of Research.
Fred McGehan | EurekAlert!
A new method for the 3-D printing of living tissues
16.08.2017 | University of Oxford
Bergamotene - alluring and lethal for Manduca sexta
21.04.2017 | Max-Planck-Institut für chemische Ökologie
Whether you call it effervescent, fizzy, or sparkling, carbonated water is making a comeback as a beverage. Aside from quenching thirst, researchers at the University of Illinois at Urbana-Champaign have discovered a new use for these "bubbly" concoctions that will have major impact on the manufacturer of the world's thinnest, flattest, and one most useful materials -- graphene.
As graphene's popularity grows as an advanced "wonder" material, the speed and quality at which it can be manufactured will be paramount. With that in mind,...
Physicists at the University of Bonn have managed to create optical hollows and more complex patterns into which the light of a Bose-Einstein condensate flows. The creation of such highly low-loss structures for light is a prerequisite for complex light circuits, such as for quantum information processing for a new generation of computers. The researchers are now presenting their results in the journal Nature Photonics.
Light particles (photons) occur as tiny, indivisible portions. Many thousands of these light portions can be merged to form a single super-photon if they are...
For the first time, scientists have shown that circular RNA is linked to brain function. When a RNA molecule called Cdr1as was deleted from the genome of mice, the animals had problems filtering out unnecessary information – like patients suffering from neuropsychiatric disorders.
While hundreds of circular RNAs (circRNAs) are abundant in mammalian brains, one big question has remained unanswered: What are they actually good for? In the...
An experimental small satellite has successfully collected and delivered data on a key measurement for predicting changes in Earth's climate.
The Radiometer Assessment using Vertically Aligned Nanotubes (RAVAN) CubeSat was launched into low-Earth orbit on Nov. 11, 2016, in order to test new...
A study led by scientists of the Max Planck Institute for the Structure and Dynamics of Matter (MPSD) at the Center for Free-Electron Laser Science in Hamburg presents evidence of the coexistence of superconductivity and “charge-density-waves” in compounds of the poorly-studied family of bismuthates. This observation opens up new perspectives for a deeper understanding of the phenomenon of high-temperature superconductivity, a topic which is at the core of condensed matter research since more than 30 years. The paper by Nicoletti et al has been published in the PNAS.
Since the beginning of the 20th century, superconductivity had been observed in some metals at temperatures only a few degrees above the absolute zero (minus...
16.08.2017 | Event News
04.08.2017 | Event News
26.07.2017 | Event News
18.08.2017 | Life Sciences
18.08.2017 | Physics and Astronomy
18.08.2017 | Materials Sciences