The micro-electromechanical device can function as a "canary on a chip" to signal cell death. (Photo courtesy of Yong Huang)
In experiments conducted at the University of California, Berkeley, researchers have found a way to tap into the telltale electrical signals that mark cell death, opening the door to the creation of a "canary on a chip" that can be used to sound the alarm of a biochemical attack or test drug toxicity on human tissue.
In a study appearing in the June 15 issue of Sensors and Actuators, researchers used a microchip to electrically determine cell viability by detecting changes in the electrical resistance of a cell membrane within milliseconds after it is exposed to a toxic agent. They found that after a cell is exposed to a toxin, its electrical resistance experiences a quick spike before dropping dramatically when it dies.
"The beauty of the device is that it detects the viability of a cell directly and instantaneously," said Boris Rubinsky, professor of mechanical engineering and bioengineering at UC Berkeley and co-author of the study, which is now available online. "This MEMS (micro-electromechanical) device will be invaluable in the detection of a biochemical attack because there you don’t have the luxury of time and analysis. It’s a new technology that will act like a canary on a chip."
Sarah Yang | UC Berkeley
Fighting myocardial infarction with nanoparticle tandems
04.12.2017 | Rheinische Friedrich-Wilhelms-Universität Bonn
Virtual Reality for Bacteria
01.12.2017 | Institute of Science and Technology Austria
What enables electrons to be transferred swiftly, for example during photosynthesis? An interdisciplinary team of researchers has worked out the details of how...
For the first time, scientists have precisely measured the effective electrical charge of a single molecule in solution. This fundamental insight of an SNSF Professor could also pave the way for future medical diagnostics.
Electrical charge is one of the key properties that allows molecules to interact. Life itself depends on this phenomenon: many biological processes involve...
At the JEC World Composite Show in Paris in March 2018, the Fraunhofer Institute for Laser Technology ILT will be focusing on the latest trends and innovations in laser machining of composites. Among other things, researchers at the booth shared with the Aachen Center for Integrative Lightweight Production (AZL) will demonstrate how lasers can be used for joining, structuring, cutting and drilling composite materials.
No other industry has attracted as much public attention to composite materials as the automotive industry, which along with the aerospace industry is a driver...
Scientists at Tokyo Institute of Technology (Tokyo Tech) and Tohoku University have developed high-quality GFO epitaxial films and systematically investigated their ferroelectric and ferromagnetic properties. They also demonstrated the room-temperature magnetocapacitance effects of these GFO thin films.
Multiferroic materials show magnetically driven ferroelectricity. They are attracting increasing attention because of their fascinating properties such as...
The oceans are the largest global heat reservoir. As a result of man-made global warming, the temperature in the global climate system increases; around 90% of...
08.01.2018 | Event News
11.12.2017 | Event News
08.12.2017 | Event News
18.01.2018 | Life Sciences
18.01.2018 | Life Sciences
18.01.2018 | Earth Sciences