Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

MelTec Forms Alliance with Fraunhofer Institute FIT

21.01.2003


Next-Generation IT Platform for Topological Proteomics to be Created



MelTec GmbH and the Fraunhofer Institute for Applied Information Technology FIT today signed a collaboration agreement to develop an information technology platform for the management and interpretation of high-throughput experiments analysing protein networks of whole cells in situ, also known as topological proteomics or toponomics. MelTec continuously generates large data sets to decipher the toponome of cells and tissues by tracing out and interpreting the context of proteins in cells.

Under this agreement, FIT and MelTec will develop new software-based approaches to analyse and visualise protein networks, and then correlate that data with results from in-vitro and in-vivo experiments. Using MelTec’s robotic toponomics imaging technology in combination with FIT’s image management and proteomics software, they will create a bioinformatics platform for the systematic interpretation of these vast protein networks. The system will rapidly produce high quality results for understanding how proteins impact a drug’s effectiveness.


"Our Topological Proteomics technologies combine cell biology and bio-mathematical tools to visualize 3-Dimensional protein-networks at the cellular and subcellular level," said Walter Schubert, M.D., Founder and Chief Executive Officer of MelTec. "This new system has the potential to become a key technology that paves the way for a more systematic approach to understanding disease pathology and treatment, by looking at how protein networks in cells determine cellular function. The alliance with FIT will accelerate our discovery program."

"Large-scale image-based experiments require advanced information management approaches that combine storage, processing and interactive exploration capabilities," said Prof. Dr. Thomas Berlage, Institute Director at the Fraunhofer Institute for Applied Information Technology FIT. "Our alliance will allow us to create an integrated environment that enables biologists to quickly identify and validate functional aspects of living cells."

About MelTec
MelTec GmbH is a privately held biotechnology company specializing in using topological proteomics to identify mechanisms underlying disease pathology, drug targets and to prioritize lead compounds focused on immune-mediated disease, neurological disorders, cancer, and arteriosclerosis. MelTec’s proprietary robotic imaging technology, MELK (Multi-Epitope-Ligand-Kartographie), performs completely automated proteomic characterization of single cells, for hundreds of proteins simultaneously, thus identifying the proteomic fingerprint, or the topology, of individual cells, such as lymphocytes. Using its technology, MelTec believes that it can greatly accelerate pre-clinical research in the drug development process, and has already identified new targets and lead compounds in amyotrophic lateral sclerosis (ALS, Lou Gehrig’s Disease) and cancer.

About Fraunhofer FIT
The Fraunhofer Institute for Applied Information Technology FIT is one of the 56 institutes of the Fraunhofer Society in Germany. FIT investigates user-oriented information and cooperation systems, focusing on the interaction of actual work practices, organizational structure and processes, in close cooperation with its clients from industry and public administration. One major application area is life science, where diagnostic and therapeutic approaches are increasingly relying on image-based technologies and integrated computerized approaches. FIT is pursuing research on novel software systems that address the anatomical, physiological and molecular levels of life.


Alex Deeg | idw
Further information:
http://www.fit.fraunhofer.de/
http://www.meltec.de/

More articles from Interdisciplinary Research:

nachricht Lego-like wall produces acoustic holograms
17.10.2016 | Duke University

nachricht New evidence on terrestrial and oceanic responses to climate change over last millennium
11.10.2016 | University of Granada

All articles from Interdisciplinary Research >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Significantly more productivity in USP lasers

In recent years, lasers with ultrashort pulses (USP) down to the femtosecond range have become established on an industrial scale. They could advance some applications with the much-lauded “cold ablation” – if that meant they would then achieve more throughput. A new generation of process engineering that will address this issue in particular will be discussed at the “4th UKP Workshop – Ultrafast Laser Technology” in April 2017.

Even back in the 1990s, scientists were comparing materials processing with nanosecond, picosecond and femtosesecond pulses. The result was surprising:...

Im Focus: Shape matters when light meets atom

Mapping the interaction of a single atom with a single photon may inform design of quantum devices

Have you ever wondered how you see the world? Vision is about photons of light, which are packets of energy, interacting with the atoms or molecules in what...

Im Focus: Novel silicon etching technique crafts 3-D gradient refractive index micro-optics

A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.

Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...

Im Focus: Quantum Particles Form Droplets

In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.

“Our Quantum droplets are in the gas phase but they still drop like a rock,” explains experimental physicist Francesca Ferlaino when talking about the...

Im Focus: MADMAX: Max Planck Institute for Physics takes up axion research

The Max Planck Institute for Physics (MPP) is opening up a new research field. A workshop from November 21 - 22, 2016 will mark the start of activities for an innovative axion experiment. Axions are still only purely hypothetical particles. Their detection could solve two fundamental problems in particle physics: What dark matter consists of and why it has not yet been possible to directly observe a CP violation for the strong interaction.

The “MADMAX” project is the MPP’s commitment to axion research. Axions are so far only a theoretical prediction and are difficult to detect: on the one hand,...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

ICTM Conference 2017: Production technology for turbomachine manufacturing of the future

16.11.2016 | Event News

Innovation Day Laser Technology – Laser Additive Manufacturing

01.11.2016 | Event News

#IC2S2: When Social Science meets Computer Science - GESIS will host the IC2S2 conference 2017

14.10.2016 | Event News

 
Latest News

Closing the carbon loop

08.12.2016 | Life Sciences

Applicability of dynamic facilitation theory to binary hard disk systems

08.12.2016 | Physics and Astronomy

Scientists track chemical and structural evolution of catalytic nanoparticles in 3-D

08.12.2016 | Materials Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>