Researchers at Los Alamos National Laboratory and the University of California, San Diego, have created the first computer simulation of full-system protein folding thermodynamics at the atomic-level. Understanding the basic physics of protein folding could solve one of the grand mysteries of computational biology.
Proteins are the basic building blocks of life and protein folding, the process by which proteins reconfigure themselves - the actions that result in structural change - are the foundation of cellular growth and the health of a biological system. When proteins incorrectly fold the malfunction can give rise to a variety of diseases. The fact that proteins fold has been known since the 1960s, but an understanding of the chemical and physical properties of folding continues to elude scientists.
Understanding how proteins undergo the folding process has largely been studied from a biologist’s point of view, probing actual proteins and studying them with high-powered microscopy techniques. Now, Los Alamos theoretical biophysicist Angel Garcia, along with colleague Jose N. Onuchic of UC San Diego, have created a computer model of protein folding that focuses on the physics of the protein folding, specifically looking at the temperature changes that occur in the process.
Kevin Roark | EurekAlert!
Lego-like wall produces acoustic holograms
17.10.2016 | Duke University
New evidence on terrestrial and oceanic responses to climate change over last millennium
11.10.2016 | University of Granada
Ultrafast lasers have introduced new possibilities in engraving ultrafine structures, and scientists are now also investigating how to use them to etch microstructures into thin glass. There are possible applications in analytics (lab on a chip) and especially in electronics and the consumer sector, where great interest has been shown.
This new method was born of a surprising phenomenon: irradiating glass in a particular way with an ultrafast laser has the effect of making the glass up to a...
Terahertz excitation of selected crystal vibrations leads to an effective magnetic field that drives coherent spin motion
Controlling functional properties by light is one of the grand goals in modern condensed matter physics and materials science. A new study now demonstrates how...
Researchers from the Institute for Quantum Computing (IQC) at the University of Waterloo led the development of a new extensible wiring technique capable of controlling superconducting quantum bits, representing a significant step towards to the realization of a scalable quantum computer.
"The quantum socket is a wiring method that uses three-dimensional wires based on spring-loaded pins to address individual qubits," said Jeremy Béjanin, a PhD...
In a paper in Scientific Reports, a research team at Worcester Polytechnic Institute describes a novel light-activated phenomenon that could become the basis for applications as diverse as microscopic robotic grippers and more efficient solar cells.
A research team at Worcester Polytechnic Institute (WPI) has developed a revolutionary, light-activated semiconductor nanocomposite material that can be used...
By forcefully embedding two silicon atoms in a diamond matrix, Sandia researchers have demonstrated for the first time on a single chip all the components needed to create a quantum bridge to link quantum computers together.
"People have already built small quantum computers," says Sandia researcher Ryan Camacho. "Maybe the first useful one won't be a single giant quantum computer...
14.10.2016 | Event News
14.10.2016 | Event News
12.10.2016 | Event News
27.10.2016 | Materials Sciences
27.10.2016 | Physics and Astronomy
27.10.2016 | Life Sciences