Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:


Launch of the European research project CARS Explorer

The CARS Explorer project, coordinated by Didier Marguet from the French National Institute for Health and Medical Research (Inserm Unit 631, CIML, Marseille), was officially launched in April in Marseille, France.

CARS Explorer is a collaborative research project funded by the European Commission under the Health priority of the 7th Framework Programme. This highly interdisciplinary consortium brings together internationally renowned physicists, biologists and clinicians of six institutional bodies from four European countries and a French SME.

Financed for three years, CARS Explorer seeks to demonstrate the concept of innovative light-based contrasting technologies for functional in situ imaging in life science and biomedical research. The ultimate goal of the consortium is to develop an endoscope based on non-linear optics (NLO) and laser pulse phase shaping.

Today, NLO technologies allow primarily low-depth exploration. However, they present major opportunities at the morphological and molecular level which makes it an original tool for biomedical analysis without requiring preliminary sample preparation, thus providing real time information to the patients.

To bring the concept to the diagnostic level, Cars Explorer partners will explore the molecular and morphological NLO signatures associated with tumour development in skin cancer, one of the fastest growing cancers in Europe with an incidence increase of 5 to 7 % a year. (Source: Ligue contre le Cancer). The consortium will concentrate its efforts on the so designated Coherent Anti-Stokes Raman Scattering (CARS) microscopy technique which permits to produce real time 3D images of cells and tissues at a molecular level, without any labelling or staining.

The development of this novel imaging technology will allow an efficient use of our knowledge of cancer molecular modifications. Indeed, this project will have a major strategic and economic impact by providing a non-invasive functional exploration method for clinical research and treatment, in particular for the prevention, diagnosis and monitoring of cancer. In the end, “an imaging technology capable of providing in vivo information both at the cellular and molecular level would be an outstanding and decisive breakthrough. It is certain that such approaches will play an increasingly central part in oncology and clinical research as well in the treatment of patients affected by cancer” says Didier Marguet.

The CARS Explorer consortium is coordinated by the French National Institute for the Health and Medical research (Inserm) and includes the French National Centre for Scientific Research (CNRS), the de Duve Institute (Belgium), the University of Stuttgart (Germany), the University of Bath (UK), Mauna Kea Technologies SAS (a French SME specialised in minimally-invasive biomedical imaging) and Inserm Transfert SA (France).

Céline Cortot | alfa
Further information:

More articles from Interdisciplinary Research:

nachricht Lego-like wall produces acoustic holograms
17.10.2016 | Duke University

nachricht New evidence on terrestrial and oceanic responses to climate change over last millennium
11.10.2016 | University of Granada

All articles from Interdisciplinary Research >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Etching Microstructures with Lasers

Ultrafast lasers have introduced new possibilities in engraving ultrafine structures, and scientists are now also investigating how to use them to etch microstructures into thin glass. There are possible applications in analytics (lab on a chip) and especially in electronics and the consumer sector, where great interest has been shown.

This new method was born of a surprising phenomenon: irradiating glass in a particular way with an ultrafast laser has the effect of making the glass up to a...

Im Focus: Light-driven atomic rotations excite magnetic waves

Terahertz excitation of selected crystal vibrations leads to an effective magnetic field that drives coherent spin motion

Controlling functional properties by light is one of the grand goals in modern condensed matter physics and materials science. A new study now demonstrates how...

Im Focus: New 3-D wiring technique brings scalable quantum computers closer to reality

Researchers from the Institute for Quantum Computing (IQC) at the University of Waterloo led the development of a new extensible wiring technique capable of controlling superconducting quantum bits, representing a significant step towards to the realization of a scalable quantum computer.

"The quantum socket is a wiring method that uses three-dimensional wires based on spring-loaded pins to address individual qubits," said Jeremy Béjanin, a PhD...

Im Focus: Scientists develop a semiconductor nanocomposite material that moves in response to light

In a paper in Scientific Reports, a research team at Worcester Polytechnic Institute describes a novel light-activated phenomenon that could become the basis for applications as diverse as microscopic robotic grippers and more efficient solar cells.

A research team at Worcester Polytechnic Institute (WPI) has developed a revolutionary, light-activated semiconductor nanocomposite material that can be used...

Im Focus: Diamonds aren't forever: Sandia, Harvard team create first quantum computer bridge

By forcefully embedding two silicon atoms in a diamond matrix, Sandia researchers have demonstrated for the first time on a single chip all the components needed to create a quantum bridge to link quantum computers together.

"People have already built small quantum computers," says Sandia researcher Ryan Camacho. "Maybe the first useful one won't be a single giant quantum computer...

All Focus news of the innovation-report >>>



Event News

#IC2S2: When Social Science meets Computer Science - GESIS will host the IC2S2 conference 2017

14.10.2016 | Event News

Agricultural Trade Developments and Potentials in Central Asia and the South Caucasus

14.10.2016 | Event News

World Health Summit – Day Three: A Call to Action

12.10.2016 | Event News

Latest News

Ice shelf vibrations cause unusual waves in Antarctic atmosphere

25.10.2016 | Earth Sciences

Fluorescent holography: Upending the world of biological imaging

25.10.2016 | Power and Electrical Engineering

Etching Microstructures with Lasers

25.10.2016 | Process Engineering

More VideoLinks >>>