In this study the computational Biomechanics group lead by Fulvia Taddei at the Medical Technology Lab of the Rizzoli Orthopaedic Institute in Bologna, Italy, reports about an extensive validation study of the so-called subject-specific finite element analysis. This method makes possible the creation of computer models capable of predicting the mechanical stresses in any region of the skeleton of a given patient, starting only from a Computed Tomography exam of that subject.
In the study eight cadaver bones instrumented with dozen of sensors and subjected to multiple physiological loading conditions were used by the Experimental Biomechanics group lead by Luca Cristofolini to determine the mechanical stresses in the region of the proximal femur, consider one of the most difficult to model accurately.
Then the eight cadaver bones were examined with a standard clinical CT procedure; the eight computer models generated from these data were used to predict the mechanical stresses in the same loading conditions, and the predictions were then compared to the measured values. The study confirmed that the method developed at the Medical Technology Lab has accuracy better than 10%, which twice more accurate than any other previously published study.
This level of accuracy makes possible the introduction of these subject-specific predictive models in the clinical practice, in applications such as the prediction of the risk of fracture in osteoporotic patients, the preoperative planning of complex skeletal reconstructions in paediatric oncology or in traumatology, or the retrospective investigation of joint arthoplasties that failed in relation to biomechanical factors.
Annalisa Bandieri | alfa
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The Institute of Semiconductor Technology and the Institute of Physical and Theoretical Chemistry, both members of the Laboratory for Emerging Nanometrology (LENA), at Technische Universität Braunschweig are partners in a new European research project entitled ChipScope, which aims to develop a completely new and extremely small optical microscope capable of observing the interior of living cells in real time. A consortium of 7 partners from 5 countries will tackle this issue with very ambitious objectives during a four-year research program.
To demonstrate the usefulness of this new scientific tool, at the end of the project the developed chip-sized microscope will be used to observe in real-time...
Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.
The results will be published on March 22 in the journal „Astronomy & Astrophysics“.
Galaxy clusters are the largest gravitationally bound structures in the universe. With a typical extent of about 10 million light years, i.e. 100 times the...
Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.
Ubiquitin is a small protein that can be linked to other cellular proteins, thereby controlling and modulating their functions. The attachment occurs in many...
In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...
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