In this study the computational Biomechanics group lead by Fulvia Taddei at the Medical Technology Lab of the Rizzoli Orthopaedic Institute in Bologna, Italy, reports about an extensive validation study of the so-called subject-specific finite element analysis. This method makes possible the creation of computer models capable of predicting the mechanical stresses in any region of the skeleton of a given patient, starting only from a Computed Tomography exam of that subject.
In the study eight cadaver bones instrumented with dozen of sensors and subjected to multiple physiological loading conditions were used by the Experimental Biomechanics group lead by Luca Cristofolini to determine the mechanical stresses in the region of the proximal femur, consider one of the most difficult to model accurately.
Then the eight cadaver bones were examined with a standard clinical CT procedure; the eight computer models generated from these data were used to predict the mechanical stresses in the same loading conditions, and the predictions were then compared to the measured values. The study confirmed that the method developed at the Medical Technology Lab has accuracy better than 10%, which twice more accurate than any other previously published study.
This level of accuracy makes possible the introduction of these subject-specific predictive models in the clinical practice, in applications such as the prediction of the risk of fracture in osteoporotic patients, the preoperative planning of complex skeletal reconstructions in paediatric oncology or in traumatology, or the retrospective investigation of joint arthoplasties that failed in relation to biomechanical factors.
Annalisa Bandieri | alfa
Stable magnetic bit of three atoms
21.09.2017 | Sonderforschungsbereich 668
Drones can almost see in the dark
20.09.2017 | Universität Zürich
Our brains house extremely complex neuronal circuits, whose detailed structures are still largely unknown. This is especially true for the so-called cerebral cortex of mammals, where among other things vision, thoughts or spatial orientation are being computed. Here the rules by which nerve cells are connected to each other are only partly understood. A team of scientists around Moritz Helmstaedter at the Frankfiurt Max Planck Institute for Brain Research and Helene Schmidt (Humboldt University in Berlin) have now discovered a surprisingly precise nerve cell connectivity pattern in the part of the cerebral cortex that is responsible for orienting the individual animal or human in space.
The researchers report online in Nature (Schmidt et al., 2017. Axonal synapse sorting in medial entorhinal cortex, DOI: 10.1038/nature24005) that synapses in...
Whispering gallery mode (WGM) resonators are used to make tiny micro-lasers, sensors, switches, routers and other devices. These tiny structures rely on a...
Using ultrafast flashes of laser and x-ray radiation, scientists at the Max Planck Institute of Quantum Optics (Garching, Germany) took snapshots of the briefest electron motion inside a solid material to date. The electron motion lasted only 750 billionths of the billionth of a second before it fainted, setting a new record of human capability to capture ultrafast processes inside solids!
When x-rays shine onto solid materials or large molecules, an electron is pushed away from its original place near the nucleus of the atom, leaving a hole...
For the first time, physicists have successfully imaged spiral magnetic ordering in a multiferroic material. These materials are considered highly promising candidates for future data storage media. The researchers were able to prove their findings using unique quantum sensors that were developed at Basel University and that can analyze electromagnetic fields on the nanometer scale. The results – obtained by scientists from the University of Basel’s Department of Physics, the Swiss Nanoscience Institute, the University of Montpellier and several laboratories from University Paris-Saclay – were recently published in the journal Nature.
Multiferroics are materials that simultaneously react to electric and magnetic fields. These two properties are rarely found together, and their combined...
MBM ScienceBridge GmbH successfully negotiated a license agreement between University Medical Center Göttingen (UMG) and the biotech company Tissue Systems Holding GmbH about commercial use of a multi-well tissue plate for automated and reliable tissue engineering & drug testing.
MBM ScienceBridge GmbH successfully negotiated a license agreement between University Medical Center Göttingen (UMG) and the biotech company Tissue Systems...
19.09.2017 | Event News
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21.09.2017 | Physics and Astronomy
21.09.2017 | Life Sciences
21.09.2017 | Health and Medicine