BaSysBio (Bacillus Systems Biology) will study the global regulation of gene transcription in the model bacterium Bacillus subtilis. This bacterium has significant economic potential as a producer of enzymes and metabolites, and is used in a wide range of industries, from pharmaceutical and chemical manufacturers to the agro and food sectors. Two disease-causing bacteria, Bacillus anthracis, responsible for Anthrax, and Staphylococcus aureus, responsible for secondary infections, are objects of research as well.
BaSysBio will provide new insight into the fundamental principles that control cellular processes. Subsequently, the initiative will contribute to the identification of new biomarkers, and innovative therapeutic targets for anti-bacterial drugs.
Genedata Phylosopher has been chosen as the central management and infrastructure solution for sharing and interpreting the experimental data generated within BaSysBio. The project will adapt an array of high-throughput genomics technologies, including transcriptomics, proteomics, metabolomics, fluxomics and cell reporter assays. As quantitative molecular profiling information is key for the development of predictive mathematical models, the Genedata Phylosopher tools will be used for integrating the BaSysBio data and interpreting it in its pathway context. “Thanks to Genedata we are able to pool the various partners’ genomics and systems biology expertise across the entire network,” BaSysBio project coordinator Dr. Philippe Noirot said.
For Genedata, anticipating the evolving needs of systems biology research is an important commitment and responsibility . The company currently supports several systems biology research consortia in Europe. Dr. Othmar Pfannes, CEO of Genedata AG, stated: “The project brings together the best teams in Europe, specialized in different fields from molecular biology to computational biology. We are proud to collaborate with this world class research consortium.”
tobe freeman | alfa
Next Generation Cryptography
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An international team of researchers has discovered a new anti-cancer protein. The protein, called LHPP, prevents the uncontrolled proliferation of cancer cells in the liver. The researchers led by Prof. Michael N. Hall from the Biozentrum, University of Basel, report in “Nature” that LHPP can also serve as a biomarker for the diagnosis and prognosis of liver cancer.
The incidence of liver cancer, also known as hepatocellular carcinoma, is steadily increasing. In the last twenty years, the number of cases has almost doubled...
In just a few weeks from now, the Chinese space station Tiangong-1 will re-enter the Earth's atmosphere where it will to a large extent burn up. It is possible that some debris will reach the Earth's surface. Tiangong-1 is orbiting the Earth uncontrolled at a speed of approx. 29,000 km/h.Currently the prognosis relating to the time of impact currently lies within a window of several days. The scientists at Fraunhofer FHR have already been monitoring Tiangong-1 for a number of weeks with their TIRA system, one of the most powerful space observation radars in the world, with a view to supporting the German Space Situational Awareness Center and the ESA with their re-entry forecasts.
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Fraunhofer Institute for Organic Electronics, Electron Beam and Plasma Technology FEP, provider of research and development services for OLED lighting solutions, announces the founding of the “OLED Licht Forum” and presents latest OLED design and lighting solutions during light+building, from March 18th – 23rd, 2018 in Frankfurt a.M./Germany, at booth no. F91 in Hall 4.0.
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A new scenario seeking to explain how Mars' putative oceans came and went over the last 4 billion years implies that the oceans formed several hundred million...
For the first time, an interdisciplinary team from the University of Basel has succeeded in integrating artificial organelles into the cells of live zebrafish embryos. This innovative approach using artificial organelles as cellular implants offers new potential in treating a range of diseases, as the authors report in an article published in Nature Communications.
In the cells of higher organisms, organelles such as the nucleus or mitochondria perform a range of complex functions necessary for life. In the networks of...
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