High content data from cellular assay technologies used at Serono enable sophisticated biological profiling. These screening technologies provide insights into the biological effects of potential drug candidates, including possible toxic side effects.
To exploit these technologies, screening results need to be shared among people with different expertise, including chemists and toxicologists. Biopharmaceutical company Serono is familiar with this process, and is organized internally to ensure there is good communication between various expert groups.
To complement this process, Genedata’s result management and analysis solution Genedata Screener combines central database functions with interactive analysis tools and web-based access to databases. In step with recent developments in biomolecular screening, Genedata have developed a scientific platform to validate and analyze cellular assays.
During the course of the collaboration, Genedata extended its Screener solution, enabling Serono’s researchers to analyze and annotate their screening results more efficiently. The collaboration quickly reached the point where the software was a precise fit with Serono’s needs.
Scientists from Serono and Genedata co-authored a research presentation made at this year’s Society for Biomolecular Sciences annual meeting in Seattle, Washington. Genedata plays an important role in the exchange of knowledge at Serono, both internally and with the wider screening community.
The collaboration has progressed in stages since its initiation in 2003. In its current form, Genedata’s solution is compatible with Cellomics screening technologies and includes sophisticated Application Programming Interfaces (APIs), an important technology for web-based software applications.
Dr. Stephan Heyse, Head of Genedata Screener, explained, “We are very pleased with the way our solution has been adopted at Serono, not just within Serono’s IT department, but also in terms of integration with the company’s drug discovery processes”.
tobe freeman | alfa
Information integration and artificial intelligence for better diagnosis and therapy decisions
24.05.2017 | Fraunhofer MEVIS - Institut für Bildgestützte Medizin
World's thinnest hologram paves path to new 3-D world
18.05.2017 | RMIT University
The world's highest gain high power laser amplifier - by many orders of magnitude - has been developed in research led at the University of Strathclyde.
The researchers demonstrated the feasibility of using plasma to amplify short laser pulses of picojoule-level energy up to 100 millijoules, which is a 'gain'...
Staphylococcus aureus is a feared pathogen (MRSA, multi-resistant S. aureus) due to frequent resistances against many antibiotics, especially in hospital infections. Researchers at the Paul-Ehrlich-Institut have identified immunological processes that prevent a successful immune response directed against the pathogenic agent. The delivery of bacterial proteins with RNA adjuvant or messenger RNA (mRNA) into immune cells allows the re-direction of the immune response towards an active defense against S. aureus. This could be of significant importance for the development of an effective vaccine. PLOS Pathogens has published these research results online on 25 May 2017.
Staphylococcus aureus (S. aureus) is a bacterium that colonizes by far more than half of the skin and the mucosa of adults, usually without causing infections....
Physicists from the University of Würzburg are capable of generating identical looking single light particles at the push of a button. Two new studies now demonstrate the potential this method holds.
The quantum computer has fuelled the imagination of scientists for decades: It is based on fundamentally different phenomena than a conventional computer....
An international team of physicists has monitored the scattering behaviour of electrons in a non-conducting material in real-time. Their insights could be beneficial for radiotherapy.
We can refer to electrons in non-conducting materials as ‘sluggish’. Typically, they remain fixed in a location, deep inside an atomic composite. It is hence...
Two-dimensional magnetic structures are regarded as a promising material for new types of data storage, since the magnetic properties of individual molecular building blocks can be investigated and modified. For the first time, researchers have now produced a wafer-thin ferrimagnet, in which molecules with different magnetic centers arrange themselves on a gold surface to form a checkerboard pattern. Scientists at the Swiss Nanoscience Institute at the University of Basel and the Paul Scherrer Institute published their findings in the journal Nature Communications.
Ferrimagnets are composed of two centers which are magnetized at different strengths and point in opposing directions. Two-dimensional, quasi-flat ferrimagnets...
24.05.2017 | Event News
23.05.2017 | Event News
22.05.2017 | Event News
29.05.2017 | Earth Sciences
29.05.2017 | Life Sciences
29.05.2017 | Physics and Astronomy