3D structure of a target protein from Plasmodium falciparum (Credit: SCAI Fraunhofer)
3D-representation of a ligand (red) inside proteins from Plasmodium falciparum (blue – yellow) (Credit: SCAI Fraunhofer)
Subtropical diseases lay waste to millions of people each year. In the quest to find a cure scientists are using Grid computing, the major driving force for new approaches towards collaborative large-scale science, to discover new drugs and better understand the diseases.
Last year there were about 350-500 million infections and approximately 1.3 million deaths due to malaria, mainly in the tropics. Malaria is spread by female mosquitoes, which carry protozoan parasites called Plasmodium.
Currently drug discovery seeks compounds that can inhibit or kill invading parasites and infections, but there are potentially millions of candidate compounds. It can take 10 years to discover a drug and another 10 to get it approved.
Tara Morris | alfa
Snake-inspired robot uses kirigami to move
22.02.2018 | Harvard John A. Paulson School of Engineering and Applied Sciences
Camera technology in vehicles: Low-latency image data compression
22.02.2018 | Fraunhofer-Institut für Nachrichtentechnik, Heinrich-Hertz-Institut, HHI
A newly developed laser technology has enabled physicists in the Laboratory for Attosecond Physics (jointly run by LMU Munich and the Max Planck Institute of Quantum Optics) to generate attosecond bursts of high-energy photons of unprecedented intensity. This has made it possible to observe the interaction of multiple photons in a single such pulse with electrons in the inner orbital shell of an atom.
In order to observe the ultrafast electron motion in the inner shells of atoms with short light pulses, the pulses must not only be ultrashort, but very...
A group of researchers led by Andrea Cavalleri at the Max Planck Institute for Structure and Dynamics of Matter (MPSD) in Hamburg has demonstrated a new method enabling precise measurements of the interatomic forces that hold crystalline solids together. The paper Probing the Interatomic Potential of Solids by Strong-Field Nonlinear Phononics, published online in Nature, explains how a terahertz-frequency laser pulse can drive very large deformations of the crystal.
By measuring the highly unusual atomic trajectories under extreme electromagnetic transients, the MPSD group could reconstruct how rigid the atomic bonds are...
Quantum computers may one day solve algorithmic problems which even the biggest supercomputers today can’t manage. But how do you test a quantum computer to...
For the first time, a team of researchers at the Max-Planck Institute (MPI) for Polymer Research in Mainz, Germany, has succeeded in making an integrated circuit (IC) from just a monolayer of a semiconducting polymer via a bottom-up, self-assembly approach.
In the self-assembly process, the semiconducting polymer arranges itself into an ordered monolayer in a transistor. The transistors are binary switches used...
Breakthrough provides a new concept of the design of molecular motors, sensors and electricity generators at nanoscale
Researchers from the Institute of Organic Chemistry and Biochemistry of the CAS (IOCB Prague), Institute of Physics of the CAS (IP CAS) and Palacký University...
15.02.2018 | Event News
13.02.2018 | Event News
12.02.2018 | Event News
23.02.2018 | Physics and Astronomy
23.02.2018 | Health and Medicine
23.02.2018 | Physics and Astronomy