A computer-aided approach -- based on software-that-learns -- promises to provide a new tool that helps doctors tailor the dosage of abciximab, a medicine frequently used before angioplasty to lessen the chance of heart attack.
Dr. Mirna Urquidi-Macdonald, professor of engineering science and mechanics, says, "While we tried our approach first with abciximab, it may be applicable to other medicines that have a narrow therapeutical range between under dosing and overdosing."
The approach is described in the January issue of the journal, Clinical Pharmacology and Therapeutics. The authors are Urquidi-Macdonald, who worked on the project during a sabbatical at the National Institute on Aging, Gerontology Research Center in Baltimore, Md.; Dr. Donald E. Mager, National Institute on Aging, Gerontology Research Center, Baltimore, Md.; Dr. Mary A. Mascelli, Centocor Inc., Malvern, Pa.; Bart Frederick, Centocor, Inc., Malvern; Dr. Jane Freedman, Division of Cardiology, Boston University School of Medicine; Dr. Desmond J. Fitzgerald, The Royal College of Surgeons in Ireland; Dr. Neal S. Kleiman, Division of Cardiology, Baylor College of Medicine, Houston, Texas; and Dr. Darrell R. Abernethy, National Institute on Aging, Gerontology Research Center,.
Barbara Hale | EurekAlert!
Construction of practical quantum computers radically simplified
05.12.2016 | University of Sussex
UT professor develops algorithm to improve online mapping of disaster areas
29.11.2016 | University of Tennessee at Knoxville
Physicists of the University of Würzburg have made an astonishing discovery in a specific type of topological insulators. The effect is due to the structure of the materials used. The researchers have now published their work in the journal Science.
Topological insulators are currently the hot topic in physics according to the newspaper Neue Zürcher Zeitung. Only a few weeks ago, their importance was...
In recent years, lasers with ultrashort pulses (USP) down to the femtosecond range have become established on an industrial scale. They could advance some applications with the much-lauded “cold ablation” – if that meant they would then achieve more throughput. A new generation of process engineering that will address this issue in particular will be discussed at the “4th UKP Workshop – Ultrafast Laser Technology” in April 2017.
Even back in the 1990s, scientists were comparing materials processing with nanosecond, picosecond and femtosesecond pulses. The result was surprising:...
Have you ever wondered how you see the world? Vision is about photons of light, which are packets of energy, interacting with the atoms or molecules in what...
A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.
Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...
In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.
“Our Quantum droplets are in the gas phase but they still drop like a rock,” explains experimental physicist Francesca Ferlaino when talking about the...
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