Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Researchers Manipulate Tiny, Floating Droplets on a Chip

10.12.2003


In an innovative study, researchers at North Carolina State University have designed a way to control the movement of microscopic droplets of liquid freely floating across centimeter-sized chips packed with electrodes. The discovery allows the performance of new types of chemical experiments on the microscale.

The breakthrough came as the researchers – Dr. Orlin D. Velev, assistant professor of chemical engineering, and two NC State doctoral students, Brian Prevo and Ketan Bhatt – learned how to circumvent friction by suspending the droplets of water inside a fluorinated oil, and then using electrical voltages to allow the liquid to hover over the electrical circuits of the chip. Switching the chip’s electrodes on and off – either manually or with the aid of a computer – lets researchers move the droplets across the oil surface to any location on the chip.

The chip also allows researchers to conduct experiments with mixed droplets, as liquids can be moved along different paths and then merged or encapsulated in oil or polymer droplets.



The discovery has wide-ranging scientific implications. Besides analyses and characterizations of chemical samples, the chip can serve as a tiny factory, Velev says, allowing researchers to mix droplets to test chemical reactions, for example, or add specific amounts of toxin to a cell to see how long it takes the cell to die. Velev is also eager to synthesize new particle materials or crystals inside liquids.

The research was published in the Dec. 4 edition of Nature.

“Moving droplets of liquid on solid surfaces as other researchers have done before us has a number of limitations,” Velev said. Other research in moving droplets on solid surfaces was stunted by friction if particles or solids were moved along the channels or solid surface of a chip. “But the freely suspended droplets on this microfluidic chip never touch solid walls and thus can act as reactors for materials synthesis or precipitation,” he said.

Velev’s interest in microfluidic chips stems from his lab’s work on growing self-assembling microwires by moving gold nanoparticles with alternating current in water, and his earlier work on using floating droplets as assembly sites for complex particles.

“Experiments and bioassays, or determinations of the presence or concentration of biological molecules, that we presently do with test tubes and beakers can now be done on the microscale. This device enlarges the scope and capabilities in the field of microfluidics, which is just a few years old,” Velev said.

The chip – which was simple and inexpensive to make, Velev says, and is reusable – has received a provisional patent, with application in place for a full patent.

The research is funded by Velev’s National Science Foundation Career Award and by an ARO-Stir grant.

Dr. Orlin Velev | NC State University
Further information:
http://www.ncsu.edu/

More articles from Information Technology:

nachricht Information integration and artificial intelligence for better diagnosis and therapy decisions
24.05.2017 | Fraunhofer MEVIS - Institut für Bildgestützte Medizin

nachricht World's thinnest hologram paves path to new 3-D world
18.05.2017 | RMIT University

All articles from Information Technology >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Can the immune system be boosted against Staphylococcus aureus by delivery of messenger RNA?

Staphylococcus aureus is a feared pathogen (MRSA, multi-resistant S. aureus) due to frequent resistances against many antibiotics, especially in hospital infections. Researchers at the Paul-Ehrlich-Institut have identified immunological processes that prevent a successful immune response directed against the pathogenic agent. The delivery of bacterial proteins with RNA adjuvant or messenger RNA (mRNA) into immune cells allows the re-direction of the immune response towards an active defense against S. aureus. This could be of significant importance for the development of an effective vaccine. PLOS Pathogens has published these research results online on 25 May 2017.

Staphylococcus aureus (S. aureus) is a bacterium that colonizes by far more than half of the skin and the mucosa of adults, usually without causing infections....

Im Focus: A quantum walk of photons

Physicists from the University of Würzburg are capable of generating identical looking single light particles at the push of a button. Two new studies now demonstrate the potential this method holds.

The quantum computer has fuelled the imagination of scientists for decades: It is based on fundamentally different phenomena than a conventional computer....

Im Focus: Turmoil in sluggish electrons’ existence

An international team of physicists has monitored the scattering behaviour of electrons in a non-conducting material in real-time. Their insights could be beneficial for radiotherapy.

We can refer to electrons in non-conducting materials as ‘sluggish’. Typically, they remain fixed in a location, deep inside an atomic composite. It is hence...

Im Focus: Wafer-thin Magnetic Materials Developed for Future Quantum Technologies

Two-dimensional magnetic structures are regarded as a promising material for new types of data storage, since the magnetic properties of individual molecular building blocks can be investigated and modified. For the first time, researchers have now produced a wafer-thin ferrimagnet, in which molecules with different magnetic centers arrange themselves on a gold surface to form a checkerboard pattern. Scientists at the Swiss Nanoscience Institute at the University of Basel and the Paul Scherrer Institute published their findings in the journal Nature Communications.

Ferrimagnets are composed of two centers which are magnetized at different strengths and point in opposing directions. Two-dimensional, quasi-flat ferrimagnets...

Im Focus: World's thinnest hologram paves path to new 3-D world

Nano-hologram paves way for integration of 3-D holography into everyday electronics

An Australian-Chinese research team has created the world's thinnest hologram, paving the way towards the integration of 3D holography into everyday...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Marine Conservation: IASS Contributes to UN Ocean Conference in New York on 5-9 June

24.05.2017 | Event News

AWK Aachen Machine Tool Colloquium 2017: Internet of Production for Agile Enterprises

23.05.2017 | Event News

Dortmund MST Conference presents Individualized Healthcare Solutions with micro and nanotechnology

22.05.2017 | Event News

 
Latest News

How herpesviruses win the footrace against the immune system

26.05.2017 | Life Sciences

Water forms 'spine of hydration' around DNA, group finds

26.05.2017 | Life Sciences

First Juno science results supported by University of Leicester's Jupiter 'forecast'

26.05.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>