Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Global positioning tracker may better gauge severity of peripheral artery disease

05.02.2008
A space-based technology may provide an inexpensive and more reliable way to gauge the walking capacity in many patients with peripheral artery disease (PAD), whose clogged leg arteries cause them severe pain when they walk, according to a report in Circulation: Journal of the American Heart Association.

A Global Positioning System (GPS) uses a constellation of at least 24 medium earth orbit satellites that transmit precise microwave signals. This enables a GPS receiver to determine its location, speed, direction and time.

Using the GPS and a simple computer spreadsheet, researchers traced and analyzed the maximal walking distance (MWD) of 24 PAD patients as they strolled through a public park. MWD is the maximum distance a person can walk at one time at a normal pace on a flat surface before leg pain forces them to rest.

“We found that MWD obtained at a person’s usual pace is largely superior to the MWD measured on a treadmill,” said Pierre Abraham, M.D., Ph.D., senior author of the study and a physician in the vascular investigation laboratory at University Hospital in Angers, France. “GPS may allow for a more objective measurement of walking capacity in patients with PAD.”

If additional studies confirm the findings, Abraham envisions the GPS assessing other diseases, including heart failure and low oxygen levels induced by exercise in the blood of respiratory disease patients.

PAD, which is caused by the same build-up of fatty deposits that narrow heart arteries, affects about 8 million Americans. The risk of PAD increases with age, and people with the disorder have a four to five times increased risk of dying of cardiovascular disease.

A treadmill MWD is the standard means to assess PAD severity and a key factor physicians use in proposing treatment. However, treadmill MWDs are time-consuming, must be done in vascular laboratories and don’t correlate with either the maximal walking distance or peoples’ perception of their disability resulting from PAD.

“Patients often report their walking capacity varies from one day to another and also varies from one moment to another within a single stroll,” Abraham said.

Studies using expensive professional GPS devices had previously demonstrated that the satellite-based system could accurately record the distances people walked. However, GPS’s usefulness in following PAD patients had never been tested.

To gain a better understanding of the effect of normal walking on such patients and how this compared with treadmill MWDs, the team equipped 18 men and six women with a $450 commercially available GPS device and analyzed their movements recorded as each walked in a public French park.

“GPS allows for the analysis of the distance walked, of course, but also the speed, duration of resting and the number of walking bouts over a prolonged recording period,” Abraham said.

Study participants, who ranged from 39 to 79 years old, were instructed to walk at their usual speed for at least 45 minutes, including rest breaks required by leg pain. When pain struck, they were told to stop walking rather than slow down. The length of each rest period was left up to the patient.

Analysis of the recorded data revealed that MWDs obtained outdoors were significantly better than treadmill-determined MWDs in three areas:

GPS-measured distance showed a better relationship to the treadmill than the patient’s self-estimates of how far they could walk on a flat surface before pain forced them to stop.

When participants walked unsupervised for 45 minutes outdoors, their MWD before they had to stop was greater than when they walked a hallway for six minutes with a researcher encouraging them every two minutes.

Patients had longer MWDs when they walked in the park than on a treadmill. “Most patients reported that the unconstrained outdoor walking better reflected their usual walking capacity compared to the treadmill,” Abraham said.

Researchers must resolve many clinical and technical questions before measuring MWD via satellite becomes an everyday tool for cardiologists, Abraham said. These include determining:

The reliability of measurements from one GPS device versus another from the same company, or from different companies.
The optimal sampling rate for recording data.
The optimal minimum recording time to determine a MWD under normal living conditions.

Whether patients would walk differently if asked to do so for a specific distance rather than a minimal time.

Even when all such questions are settled, Abraham does not envision GPS replacing treadmills entirely for measuring MWD. They will be needed to compare patients because the treadmill technique is standardized, he said. They also simultaneously record multiple physiological measurements, such as blood pressure, oxygen consumption and heart rate, and test patients who are uncertain about or can’t participate in GPS-based measurements.

Karen Astle | EurekAlert!
Further information:
http://www.heart.org

More articles from Information Technology:

nachricht Supercomputing the emergence of material behavior
18.05.2018 | University of Texas at Austin, Texas Advanced Computing Center

nachricht Keeping a Close Eye on Ice Loss
18.05.2018 | Alfred-Wegener-Institut, Helmholtz-Zentrum für Polar- und Meeresforschung

All articles from Information Technology >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: LZH showcases laser material processing of tomorrow at the LASYS 2018

At the LASYS 2018, from June 5th to 7th, the Laser Zentrum Hannover e.V. (LZH) will be showcasing processes for the laser material processing of tomorrow in hall 4 at stand 4E75. With blown bomb shells the LZH will present first results of a research project on civil security.

At this year's LASYS, the LZH will exhibit light-based processes such as cutting, welding, ablation and structuring as well as additive manufacturing for...

Im Focus: Self-illuminating pixels for a new display generation

There are videos on the internet that can make one marvel at technology. For example, a smartphone is casually bent around the arm or a thin-film display is rolled in all directions and with almost every diameter. From the user's point of view, this looks fantastic. From a professional point of view, however, the question arises: Is that already possible?

At Display Week 2018, scientists from the Fraunhofer Institute for Applied Polymer Research IAP will be demonstrating today’s technological possibilities and...

Im Focus: Explanation for puzzling quantum oscillations has been found

So-called quantum many-body scars allow quantum systems to stay out of equilibrium much longer, explaining experiment | Study published in Nature Physics

Recently, researchers from Harvard and MIT succeeded in trapping a record 53 atoms and individually controlling their quantum state, realizing what is called a...

Im Focus: Dozens of binaries from Milky Way's globular clusters could be detectable by LISA

Next-generation gravitational wave detector in space will complement LIGO on Earth

The historic first detection of gravitational waves from colliding black holes far outside our galaxy opened a new window to understanding the universe. A...

Im Focus: Entangled atoms shine in unison

A team led by Austrian experimental physicist Rainer Blatt has succeeded in characterizing the quantum entanglement of two spatially separated atoms by observing their light emission. This fundamental demonstration could lead to the development of highly sensitive optical gradiometers for the precise measurement of the gravitational field or the earth's magnetic field.

The age of quantum technology has long been heralded. Decades of research into the quantum world have led to the development of methods that make it possible...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Save the date: Forum European Neuroscience – 07-11 July 2018 in Berlin, Germany

02.05.2018 | Event News

Invitation to the upcoming "Current Topics in Bioinformatics: Big Data in Genomics and Medicine"

13.04.2018 | Event News

Unique scope of UV LED technologies and applications presented in Berlin: ICULTA-2018

12.04.2018 | Event News

 
Latest News

Designer cells: artificial enzyme can activate a gene switch

22.05.2018 | Life Sciences

PR of MCC: Carbon removal from atmosphere unavoidable for 1.5 degree target

22.05.2018 | Earth Sciences

Achema 2018: New camera system monitors distillation and helps save energy

22.05.2018 | Trade Fair News

VideoLinks
Science & Research
Overview of more VideoLinks >>>