Fraunhofer FIT will present the latest version of its Zeta Fluorescence Image Analysis software at MipTec, held in Basel, Switzerland, from September 23 to 25, 2014. Zeta, now extended to a software platform, supports the complete work process of finding new pharmaceutical agents. At MipTec, Fraunhofer FIT will demo advanced Zeta applications in cancer research and tissue analysis.
The new Zeta software platform allows researchers to implement specific imaging workflows for a broad range of applications in drug research very easily. The software was developed specifically for high content analysis of live cell imaging data that monitor and record the complete life cycle of cells.
The particular challenge for image analysis here is to detect the different phases of cell modification and cell division, and to record their temporal relationship. On this basis, a special visualization tool makes it easy to explore the data, to find individual differences and to determine the causes for different reactions of the cells.
“Using Zeta, researchers can analyze complex processes in the division of cells very easily and intuitively. A simple user interface guides them through the entire analysis workflow. And due to the evolution of Zeta into a modular software platform, we can now implement new applications much faster and thus at lower cost for our clients”, Dr. Andreas Pippow, Fraunhofer Institute for Applied Information Technology FIT, points out the main advantages of the latest Zeta version.
New software interfaces in the new version make it easier to integrate Zeta into all-encompassing high content analysis workflows. Imaging software often exists only as an isolated application – which was true also for earlier Zeta versions. What users need, however, is full integration with image data management and statistical analyses. Only if all steps in the entire workflow are supported by one coherent system, the users can freely explore and exploit their data. The latest Zeta version is a significant step in this direction.
At MipTec, September 23 to 25, 2014, the Zeta developers from Fraunhofer FIT demo a Zeta application that determines the cell division rate in cell assays. It is currently being used in cancer research in a large German pharmaceutical company.
The FIT researchers also demo a Zeta application in the study of physiological functions in tissue samples. While both applications are used in the quest for new pharmaceutical agents, they apply completely different image analysis methods. In the first application, fluorescent markers identify the cells; in the second, the objects must be detected without any specific marking.
Phone +49 2241 14-2208
Alex Deeg | Fraunhofer-Institut
Cutting edge research for the industries of tomorrow – DFKI and NICT expand cooperation
21.03.2017 | Deutsches Forschungszentrum für Künstliche Intelligenz GmbH, DFKI
Molecular motor-powered biocomputers
20.03.2017 | Technische Universität Dresden
Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.
The results will be published on March 22 in the journal „Astronomy & Astrophysics“.
Galaxy clusters are the largest gravitationally bound structures in the universe. With a typical extent of about 10 million light years, i.e. 100 times the...
Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.
Ubiquitin is a small protein that can be linked to other cellular proteins, thereby controlling and modulating their functions. The attachment occurs in many...
In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...
Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to simulate these confined natural conditions in artificial vesicles for the first time. As reported in the academic journal Small, the results are offering better insight into the development of nanoreactors and artificial organelles.
Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to...
20.03.2017 | Event News
14.03.2017 | Event News
07.03.2017 | Event News
27.03.2017 | Earth Sciences
27.03.2017 | Life Sciences
27.03.2017 | Life Sciences