Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

When Clinicians and Researchers Look Outside the Box - 1st ECRC “Franz-Volhard” Symposium at the MDC

07.09.2012
What does the immune system have to do with blood pressure, and what does the hypertension enzyme ACE have to do with the immune system and cancer?
These are questions researchers and clinicians from various disciplines will discuss at the 1st ECRC Franz Volhard Symposium in the Max Delbrück Communications Center (MDC.C) in Berlin-Buch on September 7-8, 2012. The dinner speaker will be Professor Francis Schwarze, a materials scientist at the Swiss Federal Laboratories for Materials Science and Technology (Empa) in St. Gallen, Switzerland). He has developed a method that makes a new violin sound almost like a Stradivarius.

Professor Annette Grüters-Kieslich, dean of the Charité – Universitätsmedizin Berlin, highlighted the importance of linking basic research with clinical research at the beginning of the symposium. “The aim of this close collaboration is to provide a fast track for using the insights gained from basic research for diagnosis and therapy in patients.“

“Interdisciplinary collaboration between researchers and clinicians has been the guiding principle of the Max Delbrück Center for Molecular Medicine (MDC) Berlin-Buch since its founding 20 years ago,” said Professor Walter Rosenthal, chairman of the board of directors and scientific director of the MDC. He also stressed the importance of the Experimental and Clinical Research Center (ECRC) for clinical research. The MDC and Charité – Universitätsmedizin have operated the ECRC jointly on Campus Berlin-Buch since 2007, and each contributes six million euros annually to fund the ECRC. Remarking on the planned closer institutional links between the MDC and the Charité, Professor Grüters-Kieslich and Professor Rosenthal added, “We want to continue to expand in the future what we have successfully begun here on a small scale.”

The organizers of the symposium, Professor Friedrich Luft, director of the ECRC, and Professor Dominik Müller (ECRC) seek to demonstrate that researchers and clinicians can gain surprising new insights, e.g. into the pathogenesis of serious diseases, when they look outside the box of their own fields. Current research has shown that the immune system is not only responsible for the defense against diseases, but can also affect the body’s salt and fluid balance as well as blood pressure. A report on this topic will be given by Professor Jens Titze (University of Vanderbilt, Nashville, Tennessee, USA and the University of Erlangen), one of the leading experts in this field, at the Berlin symposium.

Professor Ken Bernstein (Cedars-Sinai Medical Center, Los Angeles, California, USA) will present new insights on an enzyme (ACE, angiotensin converting enzyme), which among other functions also regulates the fluid balance of the body. New findings suggest that ACE also affects the immune system and helps inhibit the growth of tumors.

Another focus of the symposium will be on a group of factors (VEGF, vascular endothelial growth factor), which the body produces to regulate the growth of blood and lymphatic vessels. But also some tumors produce VEGF to secure their blood supply. One approach to tumor therapy is thus to block VEGF, an approach which is partly based on the research of Professor Kari Alitalo (Biomedicum Helsinki, Finland). However, the inhibition of VEGF triggers high blood pressure. Professor Alitalo will give an overview of the numerous application fields of growth factors in cardiovascular and cancer research.

A subset of these growth factors also plays an important role in high blood pressure during pregnancy (preeclampsia), one of the most dangerous complications for mother and child. A lecture on this disease, which is very difficult to treat with drugs, will be given by Professor Ananth Karumanchi (Beth Israel Deaconess Medical Center & Harvard Medical School, Boston, Massachusetts, USA), who discovered the importance of growth factors for preeclampsia.

In his lecture at the symposium, the immunologist and Nobel laureate Professor Zinkernagel (University of Zurich, Switzerland) will give an overview of the immune system. According to his opinion, “immunological memory” plays a rather subordinate role in the protection against disease, because its development is too slow and too ineffective. Instead, the immune system must always be confronted anew with the respective pathogens to preserve a sufficient amount of antibodies and pre-activated T cells. In his view, this understanding is important to be able to maintain protective immunity in the population against old and newly occurring infectious diseases.

The two-day symposium brings together approximately 220 participants from the U.S., Denmark, Finland, France, Germany, Great Britain, the Netherlands, and Switzerland. It is named after Franz Volhard (1872 – 1950), a German specialist in internal medicine who founded nephrology as an independent discipline. His research focused on renal function, hypertension and cardiovascular diseases. He was the first scientist to recognize that kidney disease can lead to high blood pressure. His research is considered groundbreaking, and many of his findings are still valid today.

Contact:
Barbara Bachtler
Press Department
Max Delbrück Center for Molecular Medicine (MDC) Berlin-Buch
in the Helmholtz Association
Robert-Rössle-Straße 10; 13125 Berlin, Germany
Phone: +49 (0) 30 94 06 - 38 96
Fax: +49 (0) 30 94 06 - 38 33
e-mail: presse@mdc-berlin.de

Barbara Bachtler | Max-Delbrück-Centrum
Further information:
http://www.mdc-berlin.de/

More articles from Event News:

nachricht ICTM Conference 2017: Production technology for turbomachine manufacturing of the future
16.11.2016 | Fraunhofer-Institut für Produktionstechnologie IPT

nachricht Innovation Day Laser Technology – Laser Additive Manufacturing
01.11.2016 | Laser Zentrum Hannover e.V.

All articles from Event News >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Electron highway inside crystal

Physicists of the University of Würzburg have made an astonishing discovery in a specific type of topological insulators. The effect is due to the structure of the materials used. The researchers have now published their work in the journal Science.

Topological insulators are currently the hot topic in physics according to the newspaper Neue Zürcher Zeitung. Only a few weeks ago, their importance was...

Im Focus: Significantly more productivity in USP lasers

In recent years, lasers with ultrashort pulses (USP) down to the femtosecond range have become established on an industrial scale. They could advance some applications with the much-lauded “cold ablation” – if that meant they would then achieve more throughput. A new generation of process engineering that will address this issue in particular will be discussed at the “4th UKP Workshop – Ultrafast Laser Technology” in April 2017.

Even back in the 1990s, scientists were comparing materials processing with nanosecond, picosecond and femtosesecond pulses. The result was surprising:...

Im Focus: Shape matters when light meets atom

Mapping the interaction of a single atom with a single photon may inform design of quantum devices

Have you ever wondered how you see the world? Vision is about photons of light, which are packets of energy, interacting with the atoms or molecules in what...

Im Focus: Novel silicon etching technique crafts 3-D gradient refractive index micro-optics

A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.

Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...

Im Focus: Quantum Particles Form Droplets

In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.

“Our Quantum droplets are in the gas phase but they still drop like a rock,” explains experimental physicist Francesca Ferlaino when talking about the...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

ICTM Conference 2017: Production technology for turbomachine manufacturing of the future

16.11.2016 | Event News

Innovation Day Laser Technology – Laser Additive Manufacturing

01.11.2016 | Event News

#IC2S2: When Social Science meets Computer Science - GESIS will host the IC2S2 conference 2017

14.10.2016 | Event News

 
Latest News

Researchers identify potentially druggable mutant p53 proteins that promote cancer growth

09.12.2016 | Life Sciences

Scientists produce a new roadmap for guiding development & conservation in the Amazon

09.12.2016 | Ecology, The Environment and Conservation

Satellites, airport visibility readings shed light on troops' exposure to air pollution

09.12.2016 | Health and Medicine

VideoLinks
B2B-VideoLinks
More VideoLinks >>>