Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

When Clinicians and Researchers Look Outside the Box - 1st ECRC “Franz-Volhard” Symposium at the MDC

07.09.2012
What does the immune system have to do with blood pressure, and what does the hypertension enzyme ACE have to do with the immune system and cancer?
These are questions researchers and clinicians from various disciplines will discuss at the 1st ECRC Franz Volhard Symposium in the Max Delbrück Communications Center (MDC.C) in Berlin-Buch on September 7-8, 2012. The dinner speaker will be Professor Francis Schwarze, a materials scientist at the Swiss Federal Laboratories for Materials Science and Technology (Empa) in St. Gallen, Switzerland). He has developed a method that makes a new violin sound almost like a Stradivarius.

Professor Annette Grüters-Kieslich, dean of the Charité – Universitätsmedizin Berlin, highlighted the importance of linking basic research with clinical research at the beginning of the symposium. “The aim of this close collaboration is to provide a fast track for using the insights gained from basic research for diagnosis and therapy in patients.“

“Interdisciplinary collaboration between researchers and clinicians has been the guiding principle of the Max Delbrück Center for Molecular Medicine (MDC) Berlin-Buch since its founding 20 years ago,” said Professor Walter Rosenthal, chairman of the board of directors and scientific director of the MDC. He also stressed the importance of the Experimental and Clinical Research Center (ECRC) for clinical research. The MDC and Charité – Universitätsmedizin have operated the ECRC jointly on Campus Berlin-Buch since 2007, and each contributes six million euros annually to fund the ECRC. Remarking on the planned closer institutional links between the MDC and the Charité, Professor Grüters-Kieslich and Professor Rosenthal added, “We want to continue to expand in the future what we have successfully begun here on a small scale.”

The organizers of the symposium, Professor Friedrich Luft, director of the ECRC, and Professor Dominik Müller (ECRC) seek to demonstrate that researchers and clinicians can gain surprising new insights, e.g. into the pathogenesis of serious diseases, when they look outside the box of their own fields. Current research has shown that the immune system is not only responsible for the defense against diseases, but can also affect the body’s salt and fluid balance as well as blood pressure. A report on this topic will be given by Professor Jens Titze (University of Vanderbilt, Nashville, Tennessee, USA and the University of Erlangen), one of the leading experts in this field, at the Berlin symposium.

Professor Ken Bernstein (Cedars-Sinai Medical Center, Los Angeles, California, USA) will present new insights on an enzyme (ACE, angiotensin converting enzyme), which among other functions also regulates the fluid balance of the body. New findings suggest that ACE also affects the immune system and helps inhibit the growth of tumors.

Another focus of the symposium will be on a group of factors (VEGF, vascular endothelial growth factor), which the body produces to regulate the growth of blood and lymphatic vessels. But also some tumors produce VEGF to secure their blood supply. One approach to tumor therapy is thus to block VEGF, an approach which is partly based on the research of Professor Kari Alitalo (Biomedicum Helsinki, Finland). However, the inhibition of VEGF triggers high blood pressure. Professor Alitalo will give an overview of the numerous application fields of growth factors in cardiovascular and cancer research.

A subset of these growth factors also plays an important role in high blood pressure during pregnancy (preeclampsia), one of the most dangerous complications for mother and child. A lecture on this disease, which is very difficult to treat with drugs, will be given by Professor Ananth Karumanchi (Beth Israel Deaconess Medical Center & Harvard Medical School, Boston, Massachusetts, USA), who discovered the importance of growth factors for preeclampsia.

In his lecture at the symposium, the immunologist and Nobel laureate Professor Zinkernagel (University of Zurich, Switzerland) will give an overview of the immune system. According to his opinion, “immunological memory” plays a rather subordinate role in the protection against disease, because its development is too slow and too ineffective. Instead, the immune system must always be confronted anew with the respective pathogens to preserve a sufficient amount of antibodies and pre-activated T cells. In his view, this understanding is important to be able to maintain protective immunity in the population against old and newly occurring infectious diseases.

The two-day symposium brings together approximately 220 participants from the U.S., Denmark, Finland, France, Germany, Great Britain, the Netherlands, and Switzerland. It is named after Franz Volhard (1872 – 1950), a German specialist in internal medicine who founded nephrology as an independent discipline. His research focused on renal function, hypertension and cardiovascular diseases. He was the first scientist to recognize that kidney disease can lead to high blood pressure. His research is considered groundbreaking, and many of his findings are still valid today.

Contact:
Barbara Bachtler
Press Department
Max Delbrück Center for Molecular Medicine (MDC) Berlin-Buch
in the Helmholtz Association
Robert-Rössle-Straße 10; 13125 Berlin, Germany
Phone: +49 (0) 30 94 06 - 38 96
Fax: +49 (0) 30 94 06 - 38 33
e-mail: presse@mdc-berlin.de

Barbara Bachtler | Max-Delbrück-Centrum
Further information:
http://www.mdc-berlin.de/

More articles from Event News:

nachricht Expert meeting “Health Business Connect” will connect international medical technology companies
20.04.2017 | IVAM Fachverband für Mikrotechnik

nachricht Wenn der Computer das Gehirn austrickst
18.04.2017 | Hochschule für Gestaltung Schwäbisch Gmünd

All articles from Event News >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Deep inside Galaxy M87

The nearby, giant radio galaxy M87 hosts a supermassive black hole (BH) and is well-known for its bright jet dominating the spectrum over ten orders of magnitude in frequency. Due to its proximity, jet prominence, and the large black hole mass, M87 is the best laboratory for investigating the formation, acceleration, and collimation of relativistic jets. A research team led by Silke Britzen from the Max Planck Institute for Radio Astronomy in Bonn, Germany, has found strong indication for turbulent processes connecting the accretion disk and the jet of that galaxy providing insights into the longstanding problem of the origin of astrophysical jets.

Supermassive black holes form some of the most enigmatic phenomena in astrophysics. Their enormous energy output is supposed to be generated by the...

Im Focus: A Quantum Low Pass for Photons

Physicists in Garching observe novel quantum effect that limits the number of emitted photons.

The probability to find a certain number of photons inside a laser pulse usually corresponds to a classical distribution of independent events, the so-called...

Im Focus: Microprocessors based on a layer of just three atoms

Microprocessors based on atomically thin materials hold the promise of the evolution of traditional processors as well as new applications in the field of flexible electronics. Now, a TU Wien research team led by Thomas Müller has made a breakthrough in this field as part of an ongoing research project.

Two-dimensional materials, or 2D materials for short, are extremely versatile, although – or often more precisely because – they are made up of just one or a...

Im Focus: Quantum-physical Model System

Computer-assisted methods aid Heidelberg physicists in reproducing experiment with ultracold atoms

Two researchers at Heidelberg University have developed a model system that enables a better understanding of the processes in a quantum-physical experiment...

Im Focus: Glacier bacteria’s contribution to carbon cycling

Glaciers might seem rather inhospitable environments. However, they are home to a diverse and vibrant microbial community. It’s becoming increasingly clear that they play a bigger role in the carbon cycle than previously thought.

A new study, now published in the journal Nature Geoscience, shows how microbial communities in melting glaciers contribute to the Earth’s carbon cycle, a...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Expert meeting “Health Business Connect” will connect international medical technology companies

20.04.2017 | Event News

Wenn der Computer das Gehirn austrickst

18.04.2017 | Event News

7th International Conference on Crystalline Silicon Photovoltaics in Freiburg on April 3-5, 2017

03.04.2017 | Event News

 
Latest News

New quantum liquid crystals may play role in future of computers

21.04.2017 | Physics and Astronomy

A promising target for kidney fibrosis

21.04.2017 | Health and Medicine

Light rays from a supernova bent by the curvature of space-time around a galaxy

21.04.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>