However, enough diclofenac remains to cause appreciable mortality (more than 10%) if birds were to take a large meal from the carcass of an animal that was given its last dose of the drug within a few days of death."
Dr Green and colleagues from the RSPB, University of Aberdeen, Bombay Natural History Society and the Zoological Society of London reported concentrations of diclofenac in tissues of treated Indian and European cattle. They found that the concentration of the drug is lower in muscle than in fat or internal organs, but declines more slowly in muscle with time since treatment (the half life of diclofenac in fat, intestine, liver and kidney is six to eight hours, compared with 15 hours in muscle).
This is the first detailed study of the exposure of vultures to diclofenac and the risk of death posed by each exposure. By improving the accuracy of the model of the relationship between diclofenac in cattle carcasses and vulture mortality, these new data will help conservationists trying to save the vultures from extinction.
According to Green: "This new information will help us to assess the danger to remaining vulture populations in Asia by using residues of diclofenac measured in field surveys of cattle and buffalo carcasses. Better means of interpreting such surveys will be essential for monitoring the effectiveness of future action taken to remove diclofenac from the food supply of vultures, such as recent government measures to restrict veterinary use of diclofenac and encourage its replacement by meloxicam."
The governments of India and Nepal have both recently placed legal restrictions on veterinary diclofenac. From 12 August 2006 the production and importation of veterinary diclofenac is no longer permitted in India, and Nepal has also recently deregistered diclofenac, preventing the manufacture or import of the drug. Both countries are promoting the use of meloxicam as a safe alternative to diclofenac.
Populations of three species of South Asian vulture - the white-backed vulture (Gyps bengalensis), the long-billed vulture (Gyps indicus) and the slender-billed vulture (Gyps tenuirostris) have declined rapidly within the last decade and all are now critically endangered. Diclofenac causes fatal kidney failure in vultures and residues of the drug have been found in most carcasses of wild vultures tested since the population decline began. “Diclofenac poisoning is the main, and possibly the only, cause of the vulture decline,” Green says.
Becky Allen | alfa
Conservationists are sounding the alarm: parrots much more threatened than assumed
15.09.2017 | Justus-Liebig-Universität Gießen
A new indicator for marine ecosystem changes: the diatom/dinoflagellate index
21.08.2017 | Leibniz-Institut für Ostseeforschung Warnemünde
Our brains house extremely complex neuronal circuits, whose detailed structures are still largely unknown. This is especially true for the so-called cerebral cortex of mammals, where among other things vision, thoughts or spatial orientation are being computed. Here the rules by which nerve cells are connected to each other are only partly understood. A team of scientists around Moritz Helmstaedter at the Frankfiurt Max Planck Institute for Brain Research and Helene Schmidt (Humboldt University in Berlin) have now discovered a surprisingly precise nerve cell connectivity pattern in the part of the cerebral cortex that is responsible for orienting the individual animal or human in space.
The researchers report online in Nature (Schmidt et al., 2017. Axonal synapse sorting in medial entorhinal cortex, DOI: 10.1038/nature24005) that synapses in...
Whispering gallery mode (WGM) resonators are used to make tiny micro-lasers, sensors, switches, routers and other devices. These tiny structures rely on a...
Using ultrafast flashes of laser and x-ray radiation, scientists at the Max Planck Institute of Quantum Optics (Garching, Germany) took snapshots of the briefest electron motion inside a solid material to date. The electron motion lasted only 750 billionths of the billionth of a second before it fainted, setting a new record of human capability to capture ultrafast processes inside solids!
When x-rays shine onto solid materials or large molecules, an electron is pushed away from its original place near the nucleus of the atom, leaving a hole...
For the first time, physicists have successfully imaged spiral magnetic ordering in a multiferroic material. These materials are considered highly promising candidates for future data storage media. The researchers were able to prove their findings using unique quantum sensors that were developed at Basel University and that can analyze electromagnetic fields on the nanometer scale. The results – obtained by scientists from the University of Basel’s Department of Physics, the Swiss Nanoscience Institute, the University of Montpellier and several laboratories from University Paris-Saclay – were recently published in the journal Nature.
Multiferroics are materials that simultaneously react to electric and magnetic fields. These two properties are rarely found together, and their combined...
MBM ScienceBridge GmbH successfully negotiated a license agreement between University Medical Center Göttingen (UMG) and the biotech company Tissue Systems Holding GmbH about commercial use of a multi-well tissue plate for automated and reliable tissue engineering & drug testing.
MBM ScienceBridge GmbH successfully negotiated a license agreement between University Medical Center Göttingen (UMG) and the biotech company Tissue Systems...
19.09.2017 | Event News
12.09.2017 | Event News
06.09.2017 | Event News
21.09.2017 | Life Sciences
21.09.2017 | Health and Medicine
21.09.2017 | Earth Sciences