While many infectious diseases are caused by human-to-human transmission, others are caused by microorganisms that exist in the outside environment. Scientists from a variety of fields, including medicine and the environment, must work together to address the challenges posed by these environmental pathogens, according to a new report, From Outside to Inside: Environmental Microorganisms as Human Pathogens, released today by the American Academy of Microbiology.
"The key difference between environmental pathogens and other human pathogens is their ability to survive and thrive outside the host. Their widespread occurrence in the environment makes them difficult to monitor and control," says Gerard Cangelosi of the Seattle Biomedical Research Institute at the University of Washington, one of the authors of the report. "The fields of medical and environmental microbiology need to be better integrated to stimulate the type of work that is required to combat environmental pathogens effectively, and the development and improvement of surveillance and reporting strategies should be a top priority."
Environmental pathogens are defined as microorganisms that normally spend a substantial part of their lifecycle outside human hosts, but when introduced to humans cause disease with measurable frequency. They are carried in the water, soil, air, food and other parts of the environment and can affect almost every individual on the planet. Some examples of environmental pathogens include Legionella pneumophila (the cause of Legionnaires disease, often found in air conditioning systems), West Nile virus, and Cryptosporidium parvum (a parasite that can be found in food, drinking water and recreational waters).
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Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to...
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