Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Long-Term Exposure to Estrogen Causes Reproductive Failure in Fish

08.11.2004


Long-term exposure to a synthetic estrogen at levels below those currently found in the environment may have a major impact on fish populations, according to a study accepted today for publication in the December issue of the peer-reviewed journal Environmental Health Perspectives (EHP). The study shows that ethynylestradiol, a potent form of estrogen used in oral contraceptives, can produce sexually compromised males.



Researchers exposed zebrafish to low concentrations of the hormone over three generations and measured the effects. After 210 days, or a full zebrafish lifetime of exposure to ethynylestradiol, second-generation fish showed reduced fertility. In addition, out of nearly 12,000 eggs spawned, none were viable. Upon examination, researchers found that none of the second-generation male fish had normal testes, and they did not produce expressible semen. However, the fish showed normal reproductive behavior patterns, including competing with healthy males.

This research suggests that the development of the testes is more sensitive to disruption by ethynylestradiol than is reproductive behavior. This could have significant population-level consequences, as infertile males have a significant ability to interfere with breeding dynamics. “Previous studies in fish have shown that endocrine disruptors can reduce sperm counts and induce female-specific proteins in males,” said Dr. Jim Burkhart, science editor for EHP. “But until now little evidence existed to show that environmentally relevant concentrations of endocrine disruptors could induce such changes and actually reduce fertility.”


The lead author of the study was Jon P. Nash, of the Katholieke Universiteit Leuven in Belgium. Other authors were David E. Kime, Leo T.M. Van der Ven, Piet W. Wester, François Brion, Gerd Maack, Petra Stahlschmidt-Allner, and Charles R. Tyler.

EHP is published by the National Institute of Environmental Health Sciences, part of the U.S. Department of Health and Human Services. EHP is an Open Access journal in January 2004.

| newswise
Further information:
http://www.ehponline.org
http://www.niehs.nih.gov

More articles from Ecology, The Environment and Conservation:

nachricht Conservationists are sounding the alarm: parrots much more threatened than assumed
15.09.2017 | Justus-Liebig-Universität Gießen

nachricht A new indicator for marine ecosystem changes: the diatom/dinoflagellate index
21.08.2017 | Leibniz-Institut für Ostseeforschung Warnemünde

All articles from Ecology, The Environment and Conservation >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: The pyrenoid is a carbon-fixing liquid droplet

Plants and algae use the enzyme Rubisco to fix carbon dioxide, removing it from the atmosphere and converting it into biomass. Algae have figured out a way to increase the efficiency of carbon fixation. They gather most of their Rubisco into a ball-shaped microcompartment called the pyrenoid, which they flood with a high local concentration of carbon dioxide. A team of scientists at Princeton University, the Carnegie Institution for Science, Stanford University and the Max Plank Institute of Biochemistry have unravelled the mysteries of how the pyrenoid is assembled. These insights can help to engineer crops that remove more carbon dioxide from the atmosphere while producing more food.

A warming planet

Im Focus: Highly precise wiring in the Cerebral Cortex

Our brains house extremely complex neuronal circuits, whose detailed structures are still largely unknown. This is especially true for the so-called cerebral cortex of mammals, where among other things vision, thoughts or spatial orientation are being computed. Here the rules by which nerve cells are connected to each other are only partly understood. A team of scientists around Moritz Helmstaedter at the Frankfiurt Max Planck Institute for Brain Research and Helene Schmidt (Humboldt University in Berlin) have now discovered a surprisingly precise nerve cell connectivity pattern in the part of the cerebral cortex that is responsible for orienting the individual animal or human in space.

The researchers report online in Nature (Schmidt et al., 2017. Axonal synapse sorting in medial entorhinal cortex, DOI: 10.1038/nature24005) that synapses in...

Im Focus: Tiny lasers from a gallery of whispers

New technique promises tunable laser devices

Whispering gallery mode (WGM) resonators are used to make tiny micro-lasers, sensors, switches, routers and other devices. These tiny structures rely on a...

Im Focus: Ultrafast snapshots of relaxing electrons in solids

Using ultrafast flashes of laser and x-ray radiation, scientists at the Max Planck Institute of Quantum Optics (Garching, Germany) took snapshots of the briefest electron motion inside a solid material to date. The electron motion lasted only 750 billionths of the billionth of a second before it fainted, setting a new record of human capability to capture ultrafast processes inside solids!

When x-rays shine onto solid materials or large molecules, an electron is pushed away from its original place near the nucleus of the atom, leaving a hole...

Im Focus: Quantum Sensors Decipher Magnetic Ordering in a New Semiconducting Material

For the first time, physicists have successfully imaged spiral magnetic ordering in a multiferroic material. These materials are considered highly promising candidates for future data storage media. The researchers were able to prove their findings using unique quantum sensors that were developed at Basel University and that can analyze electromagnetic fields on the nanometer scale. The results – obtained by scientists from the University of Basel’s Department of Physics, the Swiss Nanoscience Institute, the University of Montpellier and several laboratories from University Paris-Saclay – were recently published in the journal Nature.

Multiferroics are materials that simultaneously react to electric and magnetic fields. These two properties are rarely found together, and their combined...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

“Lasers in Composites Symposium” in Aachen – from Science to Application

19.09.2017 | Event News

I-ESA 2018 – Call for Papers

12.09.2017 | Event News

EMBO at Basel Life, a new conference on current and emerging life science research

06.09.2017 | Event News

 
Latest News

Rainbow colors reveal cell history: Uncovering β-cell heterogeneity

22.09.2017 | Life Sciences

Penn first in world to treat patient with new radiation technology

22.09.2017 | Medical Engineering

Calculating quietness

22.09.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>