Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Medicine residues may threaten fish reproduction

06.04.2010
Researchers at Umeå University and the Sahlgrenska Academy at the University of Gothenburg, Sweden, have discovered that traces of many medicines can be found in fish that have been swimming in treated waste water. One such medicine, the hormone levonorgestrel, was found in higher concentrations in the blood of fish than in women who take the contraceptive pill. Elevated levels of this hormone can lead to infertility in fish.

The study is published in the journal Environmental Science and Technology. The fish in the study were exposed to treated waste water from three sewage treatment works in Stockholm, Umeå and Gothenburg.

The study shows that levonorgestrel - which is found in many contraceptive pills, including the morning-after pill - can impact on the environment and constitutes a risk factor for the ability of fish to reproduce. Levonogestrel is designed to mimic the female sex hormone progesterone and is produced synthetically.

A study from Germany showed very recently that less than a billionth of a gram of levonorgestrel per litre inhibited the reproduction of fish in aquarium-based trials.

"We are finding these levels in treated waste water in Sweden," explains Jerker Fick at the Department of Chemistry at Umeå University.

For around ten years it has been known that synthetic oestrogen from contraceptive pills can affect fish that live downstream from sewage treatment works. The new study shows that synthetic progesterone-like hormones in contraceptive pills also carry risks.

The fish in the study were exposed to undiluted waste water, whilst in the natural environment there tends to be a degree of dilution in watercourses. But the study pointed out that there are also watercourses with very little dilution, and probably treatment plants that filter out the hormone less effectively than those included in the study. These findings will help to improve our understanding of which substances need to be removed from waste water.

"If we know how our medicines affect the environment, we will be in a better position to choose environmentally friendly alternatives, though we must always put the health of patients first," says Joakim Larsson at the Sahlgrenska Academy, one of the researchers behind the study.

CONTRACEPTIVE PILLS
Combined contraceptive pills contain synthetic forms of female sex hormones, such as synthetic oestrogen and progesterone-like hormones. The hormones that go into the pills vary between products, but levonorgestrel is a progesterone-like hormone that is used in many contraceptive pills, hormone implants and morning-after pills. It is thought that around 80-90 million women use the contraceptive pill worldwide, and that around 400,000 of them are Swedish.

The study was carried out as part of the MistraPharma research programme (www.mistrapharma.se).

For more information, please contact:
Jerker Fick, PhD and research assistant, Umeå University, tel: +46 90 786 9324, e-mail: jerker.fick@chem.umu.se

Joakim Larsson, associate professor and researcher at the Department of Physiology, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, tel: +46 31 786 3589, email: joakim.larsson@fysiologi.gu.se

Journal: Environmental Science and Technology.
Title of article: Therapeutic levels of levonorgestrel detected in blood plasma of fish: results from screening rainbow trout exposed to treated sewage effluents.

Authors: Jerker Fick, Richard H Lindberg, Jari Parkkonen, Björn Arvidsson, Mats Tysklind, D G Joakim Larsson

Helena Aaberg | idw
Further information:
http://www.gu.se
http://www.sahlgrenska.gu.se/english/news_and_events/news/News_Detail/Medicine_residues_may_threaten_fish_reproduction.cid925382

More articles from Ecology, The Environment and Conservation:

nachricht Conservationists are sounding the alarm: parrots much more threatened than assumed
15.09.2017 | Justus-Liebig-Universität Gießen

nachricht A new indicator for marine ecosystem changes: the diatom/dinoflagellate index
21.08.2017 | Leibniz-Institut für Ostseeforschung Warnemünde

All articles from Ecology, The Environment and Conservation >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: The pyrenoid is a carbon-fixing liquid droplet

Plants and algae use the enzyme Rubisco to fix carbon dioxide, removing it from the atmosphere and converting it into biomass. Algae have figured out a way to increase the efficiency of carbon fixation. They gather most of their Rubisco into a ball-shaped microcompartment called the pyrenoid, which they flood with a high local concentration of carbon dioxide. A team of scientists at Princeton University, the Carnegie Institution for Science, Stanford University and the Max Plank Institute of Biochemistry have unravelled the mysteries of how the pyrenoid is assembled. These insights can help to engineer crops that remove more carbon dioxide from the atmosphere while producing more food.

A warming planet

Im Focus: Highly precise wiring in the Cerebral Cortex

Our brains house extremely complex neuronal circuits, whose detailed structures are still largely unknown. This is especially true for the so-called cerebral cortex of mammals, where among other things vision, thoughts or spatial orientation are being computed. Here the rules by which nerve cells are connected to each other are only partly understood. A team of scientists around Moritz Helmstaedter at the Frankfiurt Max Planck Institute for Brain Research and Helene Schmidt (Humboldt University in Berlin) have now discovered a surprisingly precise nerve cell connectivity pattern in the part of the cerebral cortex that is responsible for orienting the individual animal or human in space.

The researchers report online in Nature (Schmidt et al., 2017. Axonal synapse sorting in medial entorhinal cortex, DOI: 10.1038/nature24005) that synapses in...

Im Focus: Tiny lasers from a gallery of whispers

New technique promises tunable laser devices

Whispering gallery mode (WGM) resonators are used to make tiny micro-lasers, sensors, switches, routers and other devices. These tiny structures rely on a...

Im Focus: Ultrafast snapshots of relaxing electrons in solids

Using ultrafast flashes of laser and x-ray radiation, scientists at the Max Planck Institute of Quantum Optics (Garching, Germany) took snapshots of the briefest electron motion inside a solid material to date. The electron motion lasted only 750 billionths of the billionth of a second before it fainted, setting a new record of human capability to capture ultrafast processes inside solids!

When x-rays shine onto solid materials or large molecules, an electron is pushed away from its original place near the nucleus of the atom, leaving a hole...

Im Focus: Quantum Sensors Decipher Magnetic Ordering in a New Semiconducting Material

For the first time, physicists have successfully imaged spiral magnetic ordering in a multiferroic material. These materials are considered highly promising candidates for future data storage media. The researchers were able to prove their findings using unique quantum sensors that were developed at Basel University and that can analyze electromagnetic fields on the nanometer scale. The results – obtained by scientists from the University of Basel’s Department of Physics, the Swiss Nanoscience Institute, the University of Montpellier and several laboratories from University Paris-Saclay – were recently published in the journal Nature.

Multiferroics are materials that simultaneously react to electric and magnetic fields. These two properties are rarely found together, and their combined...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

“Lasers in Composites Symposium” in Aachen – from Science to Application

19.09.2017 | Event News

I-ESA 2018 – Call for Papers

12.09.2017 | Event News

EMBO at Basel Life, a new conference on current and emerging life science research

06.09.2017 | Event News

 
Latest News

Rainbow colors reveal cell history: Uncovering β-cell heterogeneity

22.09.2017 | Life Sciences

Penn first in world to treat patient with new radiation technology

22.09.2017 | Medical Engineering

Calculating quietness

22.09.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>