Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Newly demonstrated capabilities of low-powered nanotweezers may benefit cellular-level studies

18.09.2012
Using ultra-low input power densities, researchers at the University of Illinois at Urbana-Champaign have demonstrated for the first time how low-power “optical nanotweezers” can be used to trap, manipulate, and probe nanoparticles, including fragile biological samples.

Experimental setup schematic showing laser source, microscope, and imaging detector and spectrometer. The inset illustrates the two different sample configurations that were explored; red arrows correspond to the input polarization directions and black arrows depict the propagation vector.

“We already know that plasmonic nanoantennas enhance local fields by up to several orders of magnitude, and thus, previously showed that we can use these structures with a regular CW laser source to make very good optical tweezers,” explains, Kimani Toussaint, Jr., assistant professor of mechanical science and engineering at Illinois. “This is exciting because, for the first time, we’re showing that, the near-field optical forces can be enhanced even further, without doing anything extra in terms of fabrication, but rather simply by exploiting the high-peak powers associated with using a femtosecond (fs) optical source.

“We used an average power of 50 microwatts to trap, manipulate, and probe nanoparticles. This is 100x less power than what you would get from a standard laser pointer.”

In their recent paper, “Femtosecond-pulsed plasmonic nanotweezers” published in the September 17 issue of Scientific Reports; doi:10.1038/srep00660), the researchers describe how a femtosecond-pulsed laser beam significantly augments the trapping strength of Au bowtie nanoantennas arrays (BNAs), and the first demonstration of use of femtosecond (fs) source for optical trapping with plasmonic nanotweezers.

“Our system operates at average power levels approximately three orders of magnitude lower than the expected optical damage threshold for biological structures, thereby making this technology very attractive for biological (lab-on-a-chip) applications such as cell manipulation,” added Toussaint, who is also an affiliate faculty member in the Department of Bioengineering and the Department of Electrical and Computer Engineering. “This system offers increased local diagnostic capabilities by permitting the probing of the nonlinear optical response of trapped specimens, enabling studies of in vitro fluorescent-tagged cells, or viruses using a single line for trapping and probing rather than two or more laser lines.”

"We present strong evidence that a fs source could actually augment the near-field optical forces produced by the BNAs, and most likely, other nanoantenna systems, as well. To our knowledge, this has never been demonstrated,” said Brian Roxworthy, a graduate student in Toussaint’s PROBE (Photonics Research of Bio/nano Environments) lab group and first author of the paper. According to Roxworthy, the demonstration of controlled particle fusing could be important for creating novel nanostructures, as well as for enhancing the local magnetic field response, which will be important for the field of magnetic plasmonics.

The paper also demonstrated enhancement of trap stiffness of up to 2x that of a comparable continuous-wave (CW) nanotweezers and 5x that of conventional optical tweezers that employ a fs source; successful trapping and tweezing of spherical particles ranging from 80-nm to 1.2-um in diameter, metal, dielectric, and both fluorescent and non- fluorescent particles; enhancement of two-photon fluorescent signal from trapped microparticles in comparison to the response without the presence of the BNAs; enhancement of the second-harmonic signal of ~3.5x for the combined nanoparticle-BNA system compared to the bare BNAs; and fusing of Ag nanoparticles to the BNAS.

Contact: Kimani C. Toussaint, Jr., Department of Mechanical Science & Engineering, 217/244-4088.

Kimani C. Toussaint, Jr. | EurekAlert!
Further information:
http://www.illinois.edu
http://engineering.illinois.edu/news/2012/09/17/newly-demonstrated-capabilities-low-powered-nanotweezers-may-benefit-cellular-level-

More articles from Power and Electrical Engineering:

nachricht Stretchable biofuel cells extract energy from sweat to power wearable devices
22.08.2017 | University of California - San Diego

nachricht Laser sensor LAH-G1 - optical distance sensors with measurement value display
15.08.2017 | WayCon Positionsmesstechnik GmbH

All articles from Power and Electrical Engineering >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Fizzy soda water could be key to clean manufacture of flat wonder material: Graphene

Whether you call it effervescent, fizzy, or sparkling, carbonated water is making a comeback as a beverage. Aside from quenching thirst, researchers at the University of Illinois at Urbana-Champaign have discovered a new use for these "bubbly" concoctions that will have major impact on the manufacturer of the world's thinnest, flattest, and one most useful materials -- graphene.

As graphene's popularity grows as an advanced "wonder" material, the speed and quality at which it can be manufactured will be paramount. With that in mind,...

Im Focus: Exotic quantum states made from light: Physicists create optical “wells” for a super-photon

Physicists at the University of Bonn have managed to create optical hollows and more complex patterns into which the light of a Bose-Einstein condensate flows. The creation of such highly low-loss structures for light is a prerequisite for complex light circuits, such as for quantum information processing for a new generation of computers. The researchers are now presenting their results in the journal Nature Photonics.

Light particles (photons) occur as tiny, indivisible portions. Many thousands of these light portions can be merged to form a single super-photon if they are...

Im Focus: Circular RNA linked to brain function

For the first time, scientists have shown that circular RNA is linked to brain function. When a RNA molecule called Cdr1as was deleted from the genome of mice, the animals had problems filtering out unnecessary information – like patients suffering from neuropsychiatric disorders.

While hundreds of circular RNAs (circRNAs) are abundant in mammalian brains, one big question has remained unanswered: What are they actually good for? In the...

Im Focus: RAVAN CubeSat measures Earth's outgoing energy

An experimental small satellite has successfully collected and delivered data on a key measurement for predicting changes in Earth's climate.

The Radiometer Assessment using Vertically Aligned Nanotubes (RAVAN) CubeSat was launched into low-Earth orbit on Nov. 11, 2016, in order to test new...

Im Focus: Scientists shine new light on the “other high temperature superconductor”

A study led by scientists of the Max Planck Institute for the Structure and Dynamics of Matter (MPSD) at the Center for Free-Electron Laser Science in Hamburg presents evidence of the coexistence of superconductivity and “charge-density-waves” in compounds of the poorly-studied family of bismuthates. This observation opens up new perspectives for a deeper understanding of the phenomenon of high-temperature superconductivity, a topic which is at the core of condensed matter research since more than 30 years. The paper by Nicoletti et al has been published in the PNAS.

Since the beginning of the 20th century, superconductivity had been observed in some metals at temperatures only a few degrees above the absolute zero (minus...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Call for Papers – ICNFT 2018, 5th International Conference on New Forming Technology

16.08.2017 | Event News

Sustainability is the business model of tomorrow

04.08.2017 | Event News

Clash of Realities 2017: Registration now open. International Conference at TH Köln

26.07.2017 | Event News

 
Latest News

New insights into the world of trypanosomes

23.08.2017 | Life Sciences

New Test for Rare Immunodeficiency

23.08.2017 | Life Sciences

Cholesterol-lowering drugs may fight infectious disease

22.08.2017 | Health and Medicine

VideoLinks
B2B-VideoLinks
More VideoLinks >>>