Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Synthetic biofilter wins through to the top ‘Sweet Sixteen’ in Boston

07.11.2012
Bielefeld students on a par with teams from international elite universities

Months of painstaking work in the laboratory at Bielefeld University‘s Center for Biotechnology (CeBiTec) have paid off: the 15 students participating in this year’s ‘international Genetically Engineered Machine competition’ (iGEM) at the Massachusetts Institute of Technology (MIT) have good reason to celebrate.

The goal of their project was to develop a biological filter that removes estrogen from drinking water. It was a success: they managed to produce enzymes that break down the hormone. On Monday 5 November, the competition finals came to a close in Boston.

From 190 teams throughout the world, Bielefeld’s students made it through to the ‘Sweet Sixteen’, the selection of the 16 best teams in the company of teams from such prestigious universities as Stanford University (USA), the Canadian University of Calgary, and Jiaotong University in Shanghai, China.

More than 70 teams from throughout the world got through to the finals of the top student competition in synthetic biology. The Bielefeld team was one of five German teams at the start. Bielefeld University has now participated in the iGEM competition for the third year running and already succeeded in qualifying for Boston in 2010 and 2011.

This year’s team, like its predecessors, made it into the ‘Sweet Sixteen’. ‘We stand in direct comparison with universities like Stanford and Cornell. At first, that seemed very intimidating, but we soon noticed they were having to fight exactly the same problems as we were. And with our know-how, we can match the pace here’, says Moritz Müller, a master student of molecular biotechnology.

Enzymes from fungi growing on trees filter out medicine residues from sewage and drinking water

Conventional methods of filtering waste water in sewage treatment plants are unable to completely remove medicine residues such as the estrogens in birth control pills. These residues then find their way into rivers and lakes and also accumulate in our drinking water. For fish and other aquatic life, estrogens can lead to reproductive and developmental disorders and even to the formation of female characteristics in males. The potential long-term consequences for human beings – declining sperm counts, infertility, various cancers, and osteoporosis – are still largely unknown.

The Bielefeld iGEM team has developed a biological filter in which specific enzymes (so-called laccases) break down these medicine residues. One known source of particularly efficient laccases is the turkey tail, a type of fungus that grows on trees. Using methods from synthetic biology, the students succeeded in synthesizing this enzyme and applying it to filter material.

‘We didn’t want to invent something totally crazy with our project – just because it’s technically feasible. We wanted to do something that could actually be put to use in the near future, perhaps in 20 years, and be a real benefit’, explains Robert Braun, a master student of molecular biotechnology.

‘The biofilter is such a project. And we have shown that our idea works. In principle, a company could now come along and develop our filter further. We ourselves have got to get back to our studies – most of us have rather neglected them for the last 6 months. However, the experiences we have gathered more than compensate for that’.

International competition

The iGEM competition has been held every year since 2003 by the Massachusetts Institute of Technology (MIT) in Boston. Starting as an MIT study course, the number of competitors has grown rapidly from five teams in 2004 to 190 in the present year. All teams face the same task: taking their project from the idea across the laboratory work to gaining funding and communicating the findings. On the student level, the iGEM can be seen as the world championship in synthetic biology that shows the future potential of this still young field of research. The Bielefeld iGEM team is being funded by Bielefeld University‘s Center for Biotechnology (CeBiTec) and the BIO.NRW Cluster Biotechnology North Rhine-Westphalia.

Contact:
Robert Braun, Bielefeld University
iGEM-Team Bielefeld-Germany
Telephone: 0162 3167424
Email: rbraun@igem-bielefeld.de

Ingo Lohuis | idw
Further information:
http://www.igem-bielefeld.de
http://2012.igem.org/Team:Bielefeld-Germany

More articles from Awards Funding:

nachricht Scientist at Kiel University receive EU funding to develop new implantats
22.11.2017 | Christian-Albrechts-Universität zu Kiel

nachricht Tracking down the origins of gold
08.11.2017 | Heidelberger Institut für Theoretische Studien gGmbH

All articles from Awards Funding >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Nanoparticles help with malaria diagnosis – new rapid test in development

The WHO reports an estimated 429,000 malaria deaths each year. The disease mostly affects tropical and subtropical regions and in particular the African continent. The Fraunhofer Institute for Silicate Research ISC teamed up with the Fraunhofer Institute for Molecular Biology and Applied Ecology IME and the Institute of Tropical Medicine at the University of Tübingen for a new test method to detect malaria parasites in blood. The idea of the research project “NanoFRET” is to develop a highly sensitive and reliable rapid diagnostic test so that patient treatment can begin as early as possible.

Malaria is caused by parasites transmitted by mosquito bite. The most dangerous form of malaria is malaria tropica. Left untreated, it is fatal in most cases....

Im Focus: A “cosmic snake” reveals the structure of remote galaxies

The formation of stars in distant galaxies is still largely unexplored. For the first time, astron-omers at the University of Geneva have now been able to closely observe a star system six billion light-years away. In doing so, they are confirming earlier simulations made by the University of Zurich. One special effect is made possible by the multiple reflections of images that run through the cosmos like a snake.

Today, astronomers have a pretty accurate idea of how stars were formed in the recent cosmic past. But do these laws also apply to older galaxies? For around a...

Im Focus: Visual intelligence is not the same as IQ

Just because someone is smart and well-motivated doesn't mean he or she can learn the visual skills needed to excel at tasks like matching fingerprints, interpreting medical X-rays, keeping track of aircraft on radar displays or forensic face matching.

That is the implication of a new study which shows for the first time that there is a broad range of differences in people's visual ability and that these...

Im Focus: Novel Nano-CT device creates high-resolution 3D-X-rays of tiny velvet worm legs

Computer Tomography (CT) is a standard procedure in hospitals, but so far, the technology has not been suitable for imaging extremely small objects. In PNAS, a team from the Technical University of Munich (TUM) describes a Nano-CT device that creates three-dimensional x-ray images at resolutions up to 100 nanometers. The first test application: Together with colleagues from the University of Kassel and Helmholtz-Zentrum Geesthacht the researchers analyzed the locomotory system of a velvet worm.

During a CT analysis, the object under investigation is x-rayed and a detector measures the respective amount of radiation absorbed from various angles....

Im Focus: Researchers Develop Data Bus for Quantum Computer

The quantum world is fragile; error correction codes are needed to protect the information stored in a quantum object from the deteriorating effects of noise. Quantum physicists in Innsbruck have developed a protocol to pass quantum information between differently encoded building blocks of a future quantum computer, such as processors and memories. Scientists may use this protocol in the future to build a data bus for quantum computers. The researchers have published their work in the journal Nature Communications.

Future quantum computers will be able to solve problems where conventional computers fail today. We are still far away from any large-scale implementation,...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Ecology Across Borders: International conference brings together 1,500 ecologists

15.11.2017 | Event News

Road into laboratory: Users discuss biaxial fatigue-testing for car and truck wheel

15.11.2017 | Event News

#Berlin5GWeek: The right network for Industry 4.0

30.10.2017 | Event News

 
Latest News

Corporate coworking as a driver of innovation

22.11.2017 | Business and Finance

PPPL scientists deliver new high-resolution diagnostic to national laser facility

22.11.2017 | Physics and Astronomy

Quantum optics allows us to abandon expensive lasers in spectroscopy

22.11.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>