The selection committee honoured Anne Houdusse's outstanding contributions to the field of structural biology and the understanding of the molecular mechanism of action of myosins.
The FEBS/EMBO Women in Science Award, now in its second year, recognizes and rewards the exceptional achievements of a female scientist in life sciences research over the previous five years. Winners of the award are role models who inspire future generations of women in science.
Anne Houdusse has established and clarified the molecular structure and function of myosins - a family of motor proteins vital for muscle contraction and motility processes such as cell division or transport of organelles within cells. She has transferred details seen in atomic resolution structures into functional insight and co-developed a theory that describes the movement of the molecular motors during muscle contraction.
The committee praised Anne's originality and research creativity as well as her courage to tackle difficult areas of science and persistence to achieve results.
"We are fortunate to work on a very puzzling and interesting question: how motor proteins convert chemical energy to produce force," said Anne Houdusse. "My laboratory's contribution is just one piece of this incredibly complex and important puzzle, and the current picture is the fruit of the research lead by many brilliant scientists. By trying to understand how to inhibit the activity of specific motors responsible for metastasis or cell proliferation we hope to develop therapeutic strategies against cancer."
The award winner credits the support of the Institute Curie and the dynamic collaboration with several researchers to contribute to the understanding of this fundamental problem in biology.
As group leader at the French National Research for Scientific Research (CNRS) Institute Curie in Paris, Anne Houdusse studies the structure and function of biological macromolecules, using biophysical techniques, particularly X-ray crystallography. She was a post-doctoral fellow at the Brandeis University in Massachusets, USA (1992-1998) where, with Carolyn Cohen and Andrew Szent Györgyi, she laid the foundation for her challenging work on structures of conventional myosins. At CNRS, she works closely with the US-American biologist Lee Sweeney.
The 2009 FEBS/EMBO Women in Science Award of 10,000 euro will be presented to Anne Houdusse on 5 July 2009 at the 34th FEBS Congress in Prague, Czech Republic, where she will present a special lecture.
Nominations for the 2010 FEBS/EMBO Women in Science Award close on 1 September. For more information, please visit: http://www.embo.org/gender/award.html or http://www.febs.org/women-award
Suzanne Beveridge | idw
Breakthrough Prize for Kim Nasmyth
04.12.2017 | IMP - Forschungsinstitut für Molekulare Pathologie GmbH
The key to chemical transformations
29.11.2017 | Schweizerischer Nationalfonds SNF
DNA molecules that follow specific instructions could offer more precise molecular control of synthetic chemical systems, a discovery that opens the door for engineers to create molecular machines with new and complex behaviors.
Researchers have created chemical amplifiers and a chemical oscillator using a systematic method that has the potential to embed sophisticated circuit...
MPQ scientists achieve long storage times for photonic quantum bits which break the lower bound for direct teleportation in a global quantum network.
Concerning the development of quantum memories for the realization of global quantum networks, scientists of the Quantum Dynamics Division led by Professor...
Researchers have developed a water cloaking concept based on electromagnetic forces that could eliminate an object's wake, greatly reducing its drag while...
Tiny pores at a cell's entryway act as miniature bouncers, letting in some electrically charged atoms--ions--but blocking others. Operating as exquisitely sensitive filters, these "ion channels" play a critical role in biological functions such as muscle contraction and the firing of brain cells.
To rapidly transport the right ions through the cell membrane, the tiny channels rely on a complex interplay between the ions and surrounding molecules,...
The miniaturization of the current technology of storage media is hindered by fundamental limits of quantum mechanics. A new approach consists in using so-called spin-crossover molecules as the smallest possible storage unit. Similar to normal hard drives, these special molecules can save information via their magnetic state. A research team from Kiel University has now managed to successfully place a new class of spin-crossover molecules onto a surface and to improve the molecule’s storage capacity. The storage density of conventional hard drives could therefore theoretically be increased by more than one hundred fold. The study has been published in the scientific journal Nano Letters.
Over the past few years, the building blocks of storage media have gotten ever smaller. But further miniaturization of the current technology is hindered by...
11.12.2017 | Event News
08.12.2017 | Event News
07.12.2017 | Event News
15.12.2017 | Power and Electrical Engineering
15.12.2017 | Materials Sciences
15.12.2017 | Life Sciences