Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Grant will help patients with schizophrenia who smoke

22.07.2008
A £200,000 grant has been awarded to researchers at Queen’s to help establish why people with schizophrenia are three times more likely to smoke than the general population.

It is hoped the Medical Research Council award will help the scientists discover improved treatments for nicotine dependence - which can result in increased rates of illness and death from smoking-related diseases - as well as treatments for the symptoms of schizophrenia.

The funding will provide a three-year fellowship for Dr Ruth Barr, a psychiatrist in the School of Medicine and Dentistry.

Dr Barr hopes to build on research she has carried out during a fellowship at Harvard Medical School in Massachusetts on the effects of nicotine on attention and memory in schizophrenia.

The effects of nicotine withdrawal will be measured on around 40 volunteers, including both those with and without the condition.

Dr Barr said: “The reasons behind the increased need to smoke in patients with schizophrenia are unclear, although certain symptoms of this illness may increase vulnerability to nicotine dependence.

“Schizophrenia is associated with cognitive impairments – including deficits in inhibitory control which may make it more difficult for patients to resist the impulse to smoke.

“We propose to investigate the effects of nicotine and nicotine withdrawal in smokers with and without schizophrenia on response inhibition, measured using a computer task.

“Cognitive abilities are believed to get worse during nicotine withdrawal and we want to establish if this deterioration is greater in patients with schizophrenia.

“In addition, we will investigate the mechanism of nicotine’s effects on task performance using brain scanning and a measure of brain electrical activity.

“If we can understand why patients with schizophrenia are more likely to smoke it could enable us to develop new treatments for nicotine dependence and symptoms of schizophrenia.”

Dr Barr will be supervised by Professors Stephen Cooper and Professor Gavin Reynolds from the Division of Psychiatry and Neuroscience in the School of Medicine and Dentistry.

Lisa Mitchell | alfa
Further information:
http://www.qub.ac.uk

More articles from Awards Funding:

nachricht Radio astronomers score high marks in the competition for EU funding
12.01.2017 | Max-Planck-Institut für Radioastronomie

nachricht Europe wide cooperation on spinal cord injury research receives 1.34 Million Euros grant
12.12.2016 | DFG-Forschungszentrum für Regenerative Therapien TU Dresden

All articles from Awards Funding >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Designing Architecture with Solar Building Envelopes

Among the general public, solar thermal energy is currently associated with dark blue, rectangular collectors on building roofs. Technologies are needed for aesthetically high quality architecture which offer the architect more room for manoeuvre when it comes to low- and plus-energy buildings. With the “ArKol” project, researchers at Fraunhofer ISE together with partners are currently developing two façade collectors for solar thermal energy generation, which permit a high degree of design flexibility: a strip collector for opaque façade sections and a solar thermal blind for transparent sections. The current state of the two developments will be presented at the BAU 2017 trade fair.

As part of the “ArKol – development of architecturally highly integrated façade collectors with heat pipes” project, Fraunhofer ISE together with its partners...

Im Focus: How to inflate a hardened concrete shell with a weight of 80 t

At TU Wien, an alternative for resource intensive formwork for the construction of concrete domes was developed. It is now used in a test dome for the Austrian Federal Railways Infrastructure (ÖBB Infrastruktur).

Concrete shells are efficient structures, but not very resource efficient. The formwork for the construction of concrete domes alone requires a high amount of...

Im Focus: Bacterial Pac Man molecule snaps at sugar

Many pathogens use certain sugar compounds from their host to help conceal themselves against the immune system. Scientists at the University of Bonn have now, in cooperation with researchers at the University of York in the United Kingdom, analyzed the dynamics of a bacterial molecule that is involved in this process. They demonstrate that the protein grabs onto the sugar molecule with a Pac Man-like chewing motion and holds it until it can be used. Their results could help design therapeutics that could make the protein poorer at grabbing and holding and hence compromise the pathogen in the host. The study has now been published in “Biophysical Journal”.

The cells of the mouth, nose and intestinal mucosa produce large quantities of a chemical called sialic acid. Many bacteria possess a special transport system...

Im Focus: Newly proposed reference datasets improve weather satellite data quality

UMD, NOAA collaboration demonstrates suitability of in-orbit datasets for weather satellite calibration

"Traffic and weather, together on the hour!" blasts your local radio station, while your smartphone knows the weather halfway across the world. A network of...

Im Focus: Repairing defects in fiber-reinforced plastics more efficiently

Fiber-reinforced plastics (FRP) are frequently used in the aeronautic and automobile industry. However, the repair of workpieces made of these composite materials is often less profitable than exchanging the part. In order to increase the lifetime of FRP parts and to make them more eco-efficient, the Laser Zentrum Hannover e.V. (LZH) and the Apodius GmbH want to combine a new measuring device for fiber layer orientation with an innovative laser-based repair process.

Defects in FRP pieces may be production or operation-related. Whether or not repair is cost-effective depends on the geometry of the defective area, the tools...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

12V, 48V, high-voltage – trends in E/E automotive architecture

10.01.2017 | Event News

2nd Conference on Non-Textual Information on 10 and 11 May 2017 in Hannover

09.01.2017 | Event News

Nothing will happen without batteries making it happen!

05.01.2017 | Event News

 
Latest News

Multiregional brain on a chip

16.01.2017 | Power and Electrical Engineering

New technology enables 5-D imaging in live animals, humans

16.01.2017 | Information Technology

Researchers develop environmentally friendly soy air filter

16.01.2017 | Power and Electrical Engineering

VideoLinks
B2B-VideoLinks
More VideoLinks >>>