Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Grant will help patients with schizophrenia who smoke

22.07.2008
A £200,000 grant has been awarded to researchers at Queen’s to help establish why people with schizophrenia are three times more likely to smoke than the general population.

It is hoped the Medical Research Council award will help the scientists discover improved treatments for nicotine dependence - which can result in increased rates of illness and death from smoking-related diseases - as well as treatments for the symptoms of schizophrenia.

The funding will provide a three-year fellowship for Dr Ruth Barr, a psychiatrist in the School of Medicine and Dentistry.

Dr Barr hopes to build on research she has carried out during a fellowship at Harvard Medical School in Massachusetts on the effects of nicotine on attention and memory in schizophrenia.

The effects of nicotine withdrawal will be measured on around 40 volunteers, including both those with and without the condition.

Dr Barr said: “The reasons behind the increased need to smoke in patients with schizophrenia are unclear, although certain symptoms of this illness may increase vulnerability to nicotine dependence.

“Schizophrenia is associated with cognitive impairments – including deficits in inhibitory control which may make it more difficult for patients to resist the impulse to smoke.

“We propose to investigate the effects of nicotine and nicotine withdrawal in smokers with and without schizophrenia on response inhibition, measured using a computer task.

“Cognitive abilities are believed to get worse during nicotine withdrawal and we want to establish if this deterioration is greater in patients with schizophrenia.

“In addition, we will investigate the mechanism of nicotine’s effects on task performance using brain scanning and a measure of brain electrical activity.

“If we can understand why patients with schizophrenia are more likely to smoke it could enable us to develop new treatments for nicotine dependence and symptoms of schizophrenia.”

Dr Barr will be supervised by Professors Stephen Cooper and Professor Gavin Reynolds from the Division of Psychiatry and Neuroscience in the School of Medicine and Dentistry.

Lisa Mitchell | alfa
Further information:
http://www.qub.ac.uk

More articles from Awards Funding:

nachricht Breakthrough Prize for Kim Nasmyth
04.12.2017 | IMP - Forschungsinstitut für Molekulare Pathologie GmbH

nachricht The key to chemical transformations
29.11.2017 | Schweizerischer Nationalfonds SNF

All articles from Awards Funding >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Long-lived storage of a photonic qubit for worldwide teleportation

MPQ scientists achieve long storage times for photonic quantum bits which break the lower bound for direct teleportation in a global quantum network.

Concerning the development of quantum memories for the realization of global quantum networks, scientists of the Quantum Dynamics Division led by Professor...

Im Focus: Electromagnetic water cloak eliminates drag and wake

Detailed calculations show water cloaks are feasible with today's technology

Researchers have developed a water cloaking concept based on electromagnetic forces that could eliminate an object's wake, greatly reducing its drag while...

Im Focus: Scientists channel graphene to understand filtration and ion transport into cells

Tiny pores at a cell's entryway act as miniature bouncers, letting in some electrically charged atoms--ions--but blocking others. Operating as exquisitely sensitive filters, these "ion channels" play a critical role in biological functions such as muscle contraction and the firing of brain cells.

To rapidly transport the right ions through the cell membrane, the tiny channels rely on a complex interplay between the ions and surrounding molecules,...

Im Focus: Towards data storage at the single molecule level

The miniaturization of the current technology of storage media is hindered by fundamental limits of quantum mechanics. A new approach consists in using so-called spin-crossover molecules as the smallest possible storage unit. Similar to normal hard drives, these special molecules can save information via their magnetic state. A research team from Kiel University has now managed to successfully place a new class of spin-crossover molecules onto a surface and to improve the molecule’s storage capacity. The storage density of conventional hard drives could therefore theoretically be increased by more than one hundred fold. The study has been published in the scientific journal Nano Letters.

Over the past few years, the building blocks of storage media have gotten ever smaller. But further miniaturization of the current technology is hindered by...

Im Focus: Successful Mechanical Testing of Nanowires

With innovative experiments, researchers at the Helmholtz-Zentrums Geesthacht and the Technical University Hamburg unravel why tiny metallic structures are extremely strong

Light-weight and simultaneously strong – porous metallic nanomaterials promise interesting applications as, for instance, for future aeroplanes with enhanced...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

See, understand and experience the work of the future

11.12.2017 | Event News

Innovative strategies to tackle parasitic worms

08.12.2017 | Event News

AKL’18: The opportunities and challenges of digitalization in the laser industry

07.12.2017 | Event News

 
Latest News

Gecko adhesion technology moves closer to industrial uses

13.12.2017 | Information Technology

Columbia engineers create artificial graphene in a nanofabricated semiconductor structure

13.12.2017 | Physics and Astronomy

Research reveals how diabetes in pregnancy affects baby's heart

13.12.2017 | Health and Medicine

VideoLinks
B2B-VideoLinks
More VideoLinks >>>