Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Protein design – A construction kit full of opportunities

25.03.2015

It was a very successful application for Birte Höcker. The researcher from the Max Planck Institute for Developmental Biology has now received an ERC Consolidator Grant and prize money of nearly 2 Million Euros from the European Research Council (ERC). She and her team can now follow up on new ideas about protein design, their scientific discipline.

Höcker, a biochemist, studies the evolution of proteins and uses her knowledge to construct new ones. She could already show that the diversity of proteins formed from smaller fragments, which led her to a new scientific approach: Use these parts and recombine them according to a construction kit. Fittingly, her ERC project application is called “Protein Lego”.


Dr. Birte Höcker

Jörg Abendroth / Max Planck Institute for Developmental Biology

“With this project application we follow a completely new approach to protein design”, says Birte Höcker. “We identify stable fragments of well-known protein structures, recombine them, and so we see new complex and functional proteins coming to life.”

The scientist is fascinated by the composition of these essential proteins. “In the first place, the activity of proteins makes life possible”, states Höcker. “And I am particularly interested in all these little details of their structures – how they differ from each other and why they fold the way they do.”

The deeper understanding of protein structures can help to build tailor-made proteins for use in biotechnology, medicine and synthetic biology. Protein design has a broad application range, for example creating new enzymes for manufacturing fine chemicals or degrading toxic material, for new protein based drugs or even as biosensors as tools in basic research.

“Currently we focus primarily on the basics of this technology”, Höcker underlines. Together with her research group she wants to lay the foundation, so that tailor-made proteins for specific applications can be constructed in the near future.

The ERC Grants are the most coveted awards in the European research landscape. Each year the European Research Council supports upcoming scientists of any nationality with Consolidator Grants. The awardees have to carry out excellent research projects and should have finished their doctoral degree at least seven years ago.

About Birte Höcker:
Dr. Birte Höcker finished her doctoral degree in biochemistry in 2003 at the University of Cologne, before she worked as a postdoc at the Duke University Medical Center in the USA. Since 2006, she is an Independent Research Group Leader at the Max Planck Institute for Developmental Biology in Tübingen, Germany.


About us:
The Max Planck Institute for Developmental Biology conducts basic research in the fields of biochemistry, genetics and evolutionary biology. It employs about 360 people and is located at the Max Planck Campus in Tübingen. The Max Planck Institute for Developmental Biology is one of 83 research institutes that the Max Planck Society for the Advancement of Science maintains in Germany.

Weitere Informationen:

http://www.mpg.de/9042487/erc-consolidator-grants-2014
http://erc.europa.eu/sites/default/files/press_release/files/press_release_cog20...

Nadja Winter | Max-Planck-Institut für Entwicklungsbiologie

More articles from Awards Funding:

nachricht BMBF funds translational project to improve radiotherapy
10.05.2017 | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt

nachricht Photography: An unusual and surprising picture of science
04.05.2017 | Schweizerischer Nationalfonds SNF

All articles from Awards Funding >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Wafer-thin Magnetic Materials Developed for Future Quantum Technologies

Two-dimensional magnetic structures are regarded as a promising material for new types of data storage, since the magnetic properties of individual molecular building blocks can be investigated and modified. For the first time, researchers have now produced a wafer-thin ferrimagnet, in which molecules with different magnetic centers arrange themselves on a gold surface to form a checkerboard pattern. Scientists at the Swiss Nanoscience Institute at the University of Basel and the Paul Scherrer Institute published their findings in the journal Nature Communications.

Ferrimagnets are composed of two centers which are magnetized at different strengths and point in opposing directions. Two-dimensional, quasi-flat ferrimagnets...

Im Focus: World's thinnest hologram paves path to new 3-D world

Nano-hologram paves way for integration of 3-D holography into everyday electronics

An Australian-Chinese research team has created the world's thinnest hologram, paving the way towards the integration of 3D holography into everyday...

Im Focus: Using graphene to create quantum bits

In the race to produce a quantum computer, a number of projects are seeking a way to create quantum bits -- or qubits -- that are stable, meaning they are not much affected by changes in their environment. This normally needs highly nonlinear non-dissipative elements capable of functioning at very low temperatures.

In pursuit of this goal, researchers at EPFL's Laboratory of Photonics and Quantum Measurements LPQM (STI/SB), have investigated a nonlinear graphene-based...

Im Focus: Bacteria harness the lotus effect to protect themselves

Biofilms: Researchers find the causes of water-repelling properties

Dental plaque and the viscous brown slime in drainpipes are two familiar examples of bacterial biofilms. Removing such bacterial depositions from surfaces is...

Im Focus: Hydrogen Bonds Directly Detected for the First Time

For the first time, scientists have succeeded in studying the strength of hydrogen bonds in a single molecule using an atomic force microscope. Researchers from the University of Basel’s Swiss Nanoscience Institute network have reported the results in the journal Science Advances.

Hydrogen is the most common element in the universe and is an integral part of almost all organic compounds. Molecules and sections of macromolecules are...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Dortmund MST Conference presents Individualized Healthcare Solutions with micro and nanotechnology

22.05.2017 | Event News

Innovation 4.0: Shaping a humane fourth industrial revolution

17.05.2017 | Event News

Media accreditation opens for historic year at European Health Forum Gastein

16.05.2017 | Event News

 
Latest News

New approach to revolutionize the production of molecular hydrogen

22.05.2017 | Materials Sciences

Scientists enlist engineered protein to battle the MERS virus

22.05.2017 | Life Sciences

Experts explain origins of topographic relief on Earth, Mars and Titan

22.05.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>