Cancer researcher and immunologist Professor Hua Eleanor Yu of the Beckman Research Institute, City of Hope Medical Center, Duarte, California, USA, has been awarded the Humboldt Research Award of the Alexander von Humboldt Foundation (AvH) at an award ceremony in Berlin in the evening of June 4th, 2014.
The award is connected with an invitation to spend a period of up to one year cooperating on a long-term research project with a research institution in Germany. Professor Yu selected the Max Delbrück Center for Molecular Medicine (MDC) Berlin-Buch as her host institution. With Professor Yu, a total of 36 scientists have received the prestigious award in 2014. It is valued at 60,000 EUR.
Professor Hua Eleanor Yu (Beckman Research Institute)
Professor Yu has been working for years with the immunologist Professor Thomas Blankenstein (MDC and Charité – Universitätsmedizin Berlin). The two researchers have already co-authored publications, and Professor Blankenstein was a visiting professor in Professor Yu’s laboratory in Duarte.
In Berlin Professor Yu will work together with Professor Blankenstein and colleagues to test new treatment methods based on her basic research using a model for virus-induced liver cancer developed by scientists at the MDC and which is very similar to the clinical situation.
Professor Yu’s research activities focus on a group of proteins that are crucial for the life cycles of cancer cells. Cancer cells employ a variety of survival strategies: they proliferate unchecked, elude the immune system and evade apoptosis, the body’s protective program that induces programmed cell death in defective cells.
Furthermore, they can form secondary tumors (metastases). In addition, cancer cells have a cell survival strategy against starvation. They release molecules to promote angiogenesis, the growth of a blood vessel network to provide the tumor with its own blood supply.
The regulation of all of these processes is contributed by a group of proteins called STAT (signal transducer and activator of transcription), particularly STAT3. Professor Yu is a pioneer in the STAT3 field. She was the first to discover that activated STAT3 promotes cancer growth not only by increasing tumor cell survival but also by modulating the immune system, and she showed how the protein achieves this.
STAT3 also drives the crosstalk between the cancer cells and the healthy cells in and around the tumor, thus influencing its immediate surroundings to favor tumor progression. Because of its key importance in diverse human tumors, STAT3 is regarded as a promising target for cancer therapy.
Max Delbrück Center for Molecular Medicine (MDC) Berlin-Buch
in the Helmholtz Association
Phone: +49 (0) 30 94 06 - 38 96
Fax: +49 (0) 30 94 06 - 38 33
Barbara Bachtler | Max-Delbrück-Centrum
Changing the Energy Landscape: Affordable Electricity for All
20.10.2016 | Fraunhofer-Institut für Solare Energiesysteme ISE
Emmy Noether junior research group investigates new magnetic structures for spintronics applications
11.10.2016 | Johannes Gutenberg-Universität Mainz
Researchers from the Institute for Quantum Computing (IQC) at the University of Waterloo led the development of a new extensible wiring technique capable of controlling superconducting quantum bits, representing a significant step towards to the realization of a scalable quantum computer.
"The quantum socket is a wiring method that uses three-dimensional wires based on spring-loaded pins to address individual qubits," said Jeremy Béjanin, a PhD...
In a paper in Scientific Reports, a research team at Worcester Polytechnic Institute describes a novel light-activated phenomenon that could become the basis for applications as diverse as microscopic robotic grippers and more efficient solar cells.
A research team at Worcester Polytechnic Institute (WPI) has developed a revolutionary, light-activated semiconductor nanocomposite material that can be used...
By forcefully embedding two silicon atoms in a diamond matrix, Sandia researchers have demonstrated for the first time on a single chip all the components needed to create a quantum bridge to link quantum computers together.
"People have already built small quantum computers," says Sandia researcher Ryan Camacho. "Maybe the first useful one won't be a single giant quantum computer...
COMPAMED has become the leading international marketplace for suppliers of medical manufacturing. The trade fair, which takes place every November and is co-located to MEDICA in Dusseldorf, has been steadily growing over the past years and shows that medical technology remains a rapidly growing market.
In 2016, the joint pavilion by the IVAM Microtechnology Network, the Product Market “High-tech for Medical Devices”, will be located in Hall 8a again and will...
'Ferroelectric' materials can switch between different states of electrical polarization in response to an external electric field. This flexibility means they show promise for many applications, for example in electronic devices and computer memory. Current ferroelectric materials are highly valued for their thermal and chemical stability and rapid electro-mechanical responses, but creating a material that is scalable down to the tiny sizes needed for technologies like silicon-based semiconductors (Si-based CMOS) has proven challenging.
Now, Hiroshi Funakubo and co-workers at the Tokyo Institute of Technology, in collaboration with researchers across Japan, have conducted experiments to...
14.10.2016 | Event News
14.10.2016 | Event News
12.10.2016 | Event News
21.10.2016 | Health and Medicine
21.10.2016 | Information Technology
21.10.2016 | Materials Sciences