Cancer researcher and immunologist Professor Hua Eleanor Yu of the Beckman Research Institute, City of Hope Medical Center, Duarte, California, USA, has been awarded the Humboldt Research Award of the Alexander von Humboldt Foundation (AvH) at an award ceremony in Berlin in the evening of June 4th, 2014.
The award is connected with an invitation to spend a period of up to one year cooperating on a long-term research project with a research institution in Germany. Professor Yu selected the Max Delbrück Center for Molecular Medicine (MDC) Berlin-Buch as her host institution. With Professor Yu, a total of 36 scientists have received the prestigious award in 2014. It is valued at 60,000 EUR.
Professor Hua Eleanor Yu (Beckman Research Institute)
Professor Yu has been working for years with the immunologist Professor Thomas Blankenstein (MDC and Charité – Universitätsmedizin Berlin). The two researchers have already co-authored publications, and Professor Blankenstein was a visiting professor in Professor Yu’s laboratory in Duarte.
In Berlin Professor Yu will work together with Professor Blankenstein and colleagues to test new treatment methods based on her basic research using a model for virus-induced liver cancer developed by scientists at the MDC and which is very similar to the clinical situation.
Professor Yu’s research activities focus on a group of proteins that are crucial for the life cycles of cancer cells. Cancer cells employ a variety of survival strategies: they proliferate unchecked, elude the immune system and evade apoptosis, the body’s protective program that induces programmed cell death in defective cells.
Furthermore, they can form secondary tumors (metastases). In addition, cancer cells have a cell survival strategy against starvation. They release molecules to promote angiogenesis, the growth of a blood vessel network to provide the tumor with its own blood supply.
The regulation of all of these processes is contributed by a group of proteins called STAT (signal transducer and activator of transcription), particularly STAT3. Professor Yu is a pioneer in the STAT3 field. She was the first to discover that activated STAT3 promotes cancer growth not only by increasing tumor cell survival but also by modulating the immune system, and she showed how the protein achieves this.
STAT3 also drives the crosstalk between the cancer cells and the healthy cells in and around the tumor, thus influencing its immediate surroundings to favor tumor progression. Because of its key importance in diverse human tumors, STAT3 is regarded as a promising target for cancer therapy.
Max Delbrück Center for Molecular Medicine (MDC) Berlin-Buch
in the Helmholtz Association
Phone: +49 (0) 30 94 06 - 38 96
Fax: +49 (0) 30 94 06 - 38 33
Barbara Bachtler | Max-Delbrück-Centrum
11 million Euros for research into magnetic field sensors for medical diagnostics
27.05.2016 | Christian-Albrechts-Universität zu Kiel
Laser-based Production Process for High Efficiency Solar Cells Wins Award
11.05.2016 | Fraunhofer-Institut für Solare Energiesysteme ISE
A biological and energy-efficient process, developed and patented by the University of Innsbruck, converts nitrogen compounds in wastewater treatment facilities into harmless atmospheric nitrogen gas. This innovative technology is now being refined and marketed jointly with the United States’ DC Water and Sewer Authority (DC Water). The largest DEMON®-system in a wastewater treatment plant is currently being built in Washington, DC.
The DEMON®-system was developed and patented by the University of Innsbruck 11 years ago. Today this successful technology has been implemented in about 70...
Permanent magnets are very important for technologies of the future like electromobility and renewable energy, and rare earth elements (REE) are necessary for their manufacture. The Fraunhofer Institute for Mechanics of Materials IWM in Freiburg, Germany, has now succeeded in identifying promising approaches and materials for new permanent magnets through use of an in-house simulation process based on high-throughput screening (HTS). The team was able to improve magnetic properties this way and at the same time replaced REE with elements that are less expensive and readily available. The results were published in the online technical journal “Scientific Reports”.
The starting point for IWM researchers Wolfgang Körner, Georg Krugel, and Christian Elsässer was a neodymium-iron-nitrogen compound based on a type of...
In the Beyond EUV project, the Fraunhofer Institutes for Laser Technology ILT in Aachen and for Applied Optics and Precision Engineering IOF in Jena are developing key technologies for the manufacture of a new generation of microchips using EUV radiation at a wavelength of 6.7 nm. The resulting structures are barely thicker than single atoms, and they make it possible to produce extremely integrated circuits for such items as wearables or mind-controlled prosthetic limbs.
In 1965 Gordon Moore formulated the law that came to be named after him, which states that the complexity of integrated circuits doubles every one to two...
Characterization of high-quality material reveals important details relevant to next generation nanoelectronic devices
Quantum mechanics is the field of physics governing the behavior of things on atomic scales, where things work very differently from our everyday world.
When current comes in discrete packages: Viennese scientists unravel the quantum properties of the carbon material graphene
In 2010 the Nobel Prize in physics was awarded for the discovery of the exceptional material graphene, which consists of a single layer of carbon atoms...
24.05.2016 | Event News
20.05.2016 | Event News
19.05.2016 | Event News
30.05.2016 | Power and Electrical Engineering
30.05.2016 | Ecology, The Environment and Conservation
30.05.2016 | Physics and Astronomy