Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Humboldt Research Award Granted to Cancer Researcher Hua Eleanor Yu - Host Institute: MDC

05.06.2014

Cancer researcher and immunologist Professor Hua Eleanor Yu of the Beckman Research Institute, City of Hope Medical Center, Duarte, California, USA, has been awarded the Humboldt Research Award of the Alexander von Humboldt Foundation (AvH) at an award ceremony in Berlin in the evening of June 4th, 2014.

The award is connected with an invitation to spend a period of up to one year cooperating on a long-term research project with a research institution in Germany. Professor Yu selected the Max Delbrück Center for Molecular Medicine (MDC) Berlin-Buch as her host institution. With Professor Yu, a total of 36 scientists have received the prestigious award in 2014. It is valued at 60,000 EUR.


Professor Hua Eleanor Yu (Beckman Research Institute)

(private)

Professor Yu has been working for years with the immunologist Professor Thomas Blankenstein (MDC and Charité – Universitätsmedizin Berlin). The two researchers have already co-authored publications, and Professor Blankenstein was a visiting professor in Professor Yu’s laboratory in Duarte.

In Berlin Professor Yu will work together with Professor Blankenstein and colleagues to test new treatment methods based on her basic research using a model for virus-induced liver cancer developed by scientists at the MDC and which is very similar to the clinical situation.

Professor Yu’s research activities focus on a group of proteins that are crucial for the life cycles of cancer cells. Cancer cells employ a variety of survival strategies: they proliferate unchecked, elude the immune system and evade apoptosis, the body’s protective program that induces programmed cell death in defective cells.

Furthermore, they can form secondary tumors (metastases). In addition, cancer cells have a cell survival strategy against starvation. They release molecules to promote angiogenesis, the growth of a blood vessel network to provide the tumor with its own blood supply.

The regulation of all of these processes is contributed by a group of proteins called STAT (signal transducer and activator of transcription), particularly STAT3. Professor Yu is a pioneer in the STAT3 field. She was the first to discover that activated STAT3 promotes cancer growth not only by increasing tumor cell survival but also by modulating the immune system, and she showed how the protein achieves this.

STAT3 also drives the crosstalk between the cancer cells and the healthy cells in and around the tumor, thus influencing its immediate surroundings to favor tumor progression. Because of its key importance in diverse human tumors, STAT3 is regarded as a promising target for cancer therapy.

Contact:
Barbara Bachtler
Press Department
Max Delbrück Center for Molecular Medicine (MDC) Berlin-Buch
in the Helmholtz Association
Robert-Rössle-Straße 10
13125 Berlin
Germany
Phone: +49 (0) 30 94 06 - 38 96
Fax: +49 (0) 30 94 06 - 38 33
e-mail: presse@mdc-berlin.de
http://www.mdc-berlin.de/

Weitere Informationen:

http://www.humboldt-foundation.de/web/start.html
http://www.cityofhope.org/about-city-of-hope

Barbara Bachtler | Max-Delbrück-Centrum

Further reports about: Cancer MDC Max-Delbrück-Centrum Medicine Molecular immune proteins strategies tumors

More articles from Awards Funding:

nachricht Frank Feldmann Receives SolarWorld Junior Einstein Award 2016
27.06.2016 | Fraunhofer-Institut für Solare Energiesysteme ISE

nachricht Dr. Karl-Robert Brauns Prize for Ophthalmology 2016
16.06.2016 | Max-Planck-Institut für Struktur und Dynamik der Materie

All articles from Awards Funding >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Optical lenses, hardly larger than a human hair

3D printing enables the smalles complex micro-objectives

3D printing revolutionized the manufacturing of complex shapes in the last few years. Using additive depositing of materials, where individual dots or lines...

Im Focus: Flexible OLED applications arrive

R2D2, a joint project to analyze and development high-TRL processes and technologies for manufacture of flexible organic light-emitting diodes (OLEDs) funded by the German Federal Ministry of Education and Research (BMBF) has been successfully completed.

In contrast to point light sources like LEDs made of inorganic semiconductor crystals, organic light-emitting diodes (OLEDs) are light-emitting surfaces. Their...

Im Focus: Unexpected flexibility found in odorant molecules

High resolution rotational spectroscopy reveals an unprecedented number of conformations of an odorant molecule – a new world record!

In a recent publication in the journal Physical Chemistry Chemical Physics, researchers from the Max Planck Institute for the Structure and Dynamics of Matter...

Im Focus: 3-D printing produces cartilage from strands of bioink

Strands of cow cartilage substitute for ink in a 3D bioprinting process that may one day create cartilage patches for worn out joints, according to a team of engineers. "Our goal is to create tissue that can be used to replace large amounts of worn out tissue or design patches," said Ibrahim T. Ozbolat, associate professor of engineering science and mechanics. "Those who have osteoarthritis in their joints suffer a lot. We need a new alternative treatment for this."

Cartilage is a good tissue to target for scale-up bioprinting because it is made up of only one cell type and has no blood vessels within the tissue. It is...

Im Focus: First experimental quantum simulation of particle physics phenomena

Physicists in Innsbruck have realized the first quantum simulation of lattice gauge theories, building a bridge between high-energy theory and atomic physics. In the journal Nature, Rainer Blatt‘s and Peter Zoller’s research teams describe how they simulated the creation of elementary particle pairs out of the vacuum by using a quantum computer.

Elementary particles are the fundamental buildings blocks of matter, and their properties are described by the Standard Model of particle physics. The...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

International Conference ‘GEO BON’ Wants to Close Knowledge Gaps in Global Biodiversity

28.06.2016 | Event News

ERES 2016: The largest conference in the European real estate industry

09.06.2016 | Event News

Networking 4.0: International Laser Technology Congress AKL’16 Shows New Ways of Cooperations

24.05.2016 | Event News

 
Latest News

Building a better battery

29.06.2016 | Life Sciences

New way out: Researchers show how stem cells exit bloodstream

29.06.2016 | Life Sciences

Crucial peatlands carbon-sink vulnerable to rising sea levels

29.06.2016 | Earth Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>