Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

German Research Foundation funds cardiovascular research at the Mainz University Medical Center

29.01.2013
Focused research on the involvement of inflammatory processes in the development of hypertension and arteriosclerosis

The German Research Foundation has approved funding for the Department of Internal Medicine II of the Mainz University Medical Center to promote the further study of the interrelations between the immune system and cardiovascular system disorders. The main focus of the current research project is on the pathogenesis of high blood pressure and arteriosclerosis.

PD Dr. Philip Wenzel, cardiologist and senior physician at the Department of Internal Medicine II, will use the about EUR 300,000 he has been granted for the next 36 months for staff resources and consumables. "We want to pursue the fascinating question of how the blood pressure hormone angiotensin II and the mediators of inflammation, in particular interferon gamma, interact in the pathogenesis of vascular diseases," said Wenzel.

In recent years, it has become increasingly clear that inflammatory cells, which are normally responsible for defending the body against pathogens, are also involved in the development of such frequently encountered disorders as hypertension, heart attack, stroke, and so-called 'window shopping syndrome' or intermittent claudication.

It is possible that many of the medications used to treat these illnesses, such as statins and ACE inhibitors, are only as effective as they are because they actually moderate these inflammatory processes. "Through our research, we hope to establish the foundations on which targeted anti-inflammatory therapies for arteriosclerosis can be developed and used in the future," Wenzel continued.

The successful acquisition of third-party funds is also attributable to the strategy adopted by the University Medical Center of Johannes Gutenberg University Mainz (JGU), namely that of establishing specialized research units. Within this context, the research team led by PD Dr. Philip Wenzel has managed to form partnerships that are important for the future of translational medicine.

"The work of the Research Unit Vascular Prevention and the establishment of the Center for Thrombosis and Hemostasis (CTH) with the support of the Mainz Heart Foundation have created an environment in which applications to the German Research Foundation have a greater chance of success," said Professor Dr. Thomas Münzel, Founding Director of the CTH and Coordinator of the Research Unit Vascular Prevention at the Mainz University Medical Center.

Petra Giegerich | idw
Further information:
http://www.uni-mainz.de/presse/16121_ENG_HTML.php
http://www.unimedizin-mainz.de/medical-center.html

More articles from Awards Funding:

nachricht European Research Council awards Leipzig biologist a EUR 1.5 million grant
29.01.2016 | Deutsches Zentrum für integrative Biodiversitätsforschung (iDiv) Halle-Jena-Leipzig

nachricht ERC Grant for new Therapy against Burn Scars
26.01.2016 | Universität Bremen

All articles from Awards Funding >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Production of an AIDS vaccine in algae

Today, plants and microorganisms are heavily used for the production of medicinal products. The production of biopharmaceuticals in plants, also referred to as “Molecular Pharming”, represents a continuously growing field of plant biotechnology. Preferred host organisms include yeast and crop plants, such as maize and potato – plants with high demands. With the help of a special algal strain, the research team of Prof. Ralph Bock at the Max Planck Institute of Molecular Plant Physiology in Potsdam strives to develop a more efficient and resource-saving system for the production of medicines and vaccines. They tested its practicality by synthesizing a component of a potential AIDS vaccine.

The use of plants and microorganisms to produce pharmaceuticals is nothing new. In 1982, bacteria were genetically modified to produce human insulin, a drug...

Im Focus: The most accurate optical single-ion clock worldwide

Atomic clock experts from the Physikalisch-Technische Bundesanstalt (PTB) are the first research group in the world to have built an optical single-ion clock which attains an accuracy which had only been predicted theoretically so far. Their optical ytterbium clock achieved a relative systematic measurement uncertainty of 3 E-18. The results have been published in the current issue of the scientific journal "Physical Review Letters".

Atomic clock experts from the Physikalisch-Technische Bundesanstalt (PTB) are the first research group in the world to have built an optical single-ion clock...

Im Focus: Goodbye ground control: autonomous nanosatellites

The University of Würzburg has two new space projects in the pipeline which are concerned with the observation of planets and autonomous fault correction aboard satellites. The German Federal Ministry of Economic Affairs and Energy funds the projects with around 1.6 million euros.

Detecting tornadoes that sweep across Mars. Discovering meteors that fall to Earth. Investigating strange lightning that flashes from Earth's atmosphere into...

Im Focus: Flow phenomena on solid surfaces: Physicists highlight key role played by boundary layer velocity

Physicists from Saarland University and the ESPCI in Paris have shown how liquids on solid surfaces can be made to slide over the surface a bit like a bobsleigh on ice. The key is to apply a coating at the boundary between the liquid and the surface that induces the liquid to slip. This results in an increase in the average flow velocity of the liquid and its throughput. This was demonstrated by studying the behaviour of droplets on surfaces with different coatings as they evolved into the equilibrium state. The results could prove useful in optimizing industrial processes, such as the extrusion of plastics.

The study has been published in the respected academic journal PNAS (Proceedings of the National Academy of Sciences of the United States of America).

Im Focus: New study: How stable is the West Antarctic Ice Sheet?

Exceeding critical temperature limits in the Southern Ocean may cause the collapse of ice sheets and a sharp rise in sea levels

A future warming of the Southern Ocean caused by rising greenhouse gas concentrations in the atmosphere may severely disrupt the stability of the West...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Travel grants available: Meet the world’s most proficient mathematicians and computer scientists

09.02.2016 | Event News

AKL’16: Experience Laser Technology Live in Europe´s Largest Laser Application Center!

02.02.2016 | Event News

From intelligent knee braces to anti-theft backpacks

26.01.2016 | Event News

 
Latest News

New method opens crystal clear views of biomolecules

11.02.2016 | Life Sciences

Scientists take nanoparticle snapshots

11.02.2016 | Physics and Astronomy

NASA sees development of Tropical Storm 11P in Southwestern Pacific

11.02.2016 | Earth Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>