Fulvia Bono, research group leader at the Max Planck Institute for Developmental Biology, as well as Wolfram Antonin and Michael Hothorn, both Max Planck research group leaders at the Friedrich Miescher Laboratory in Tübingen, will each be awarded a Starting Grant of the European Research Council (ERC).
Messenger RNA is combined with certain proteins to form particles, the so-called mRNP complexes. In the fruit fly Drosophila, the localization of these complexes determines the formation of the embryo’s body axis. Fulvia Bono wants to understand the function of the mRNP systems at a mechanistic level and gain deeper insight into the connection between genes and outer appearance of organisms.
During cell division, the DNA has to be contracted up to 50 times in the chromosomes to a transport form. After the formation of the new daughter cells, the DNA is unpacked again for transcription and replication. Wolfram Antonin had noticed that, while the packing of the DNA is a well-studied process, little is known of DNA decondensation. “It is possible,” the scientist says, “that DNA decondensation is a passive process, as if a clip around the DNA thread is released and the DNA just relaxes.” However, initial experiments hint at an active process. Wolfram Antonin wants to investigate this process and the proteins involved.“This is a high-risk research project, since we cannot say anything about the outcome. This is special about the ERC grants, that the sponsor trusts the skills of the scientists themselves and funds promising project ideas,” he says. Wolfram Antonin obtained his PhD at the Max Planck Institute for Biophysical Chemistry in Göttingen in 2001. After receiving post-doctoral training at the European Molecular Biology Laboratory (EMBL) in Heidelberg, he joined the Friedrich Miescher Laboratory in 2006.
Janna Eberhardt | idw
Further reports about: > DNA > ERC Advanced Grants > ERC Starting Grant > EUROS > European Molecular Biology > European Molecular Biology Laboratory > Laboratory > Max Planck Institute > Mobile phone > Molecular Biology > Molecular Biology Laboratory > Molecular Target > RNA > Starting Grants > cell cytoplasm > cell division > daughter cells > plant cell > signaling pathway > synthetic biology
Helmholtz International Fellow Award for Sarah Amalia Teichmann
20.01.2017 | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt
Scientist from Kiel University coordinates Million Euros Project in Inflammation Research
19.01.2017 | Christian-Albrechts-Universität zu Kiel
For the first time ever, a cloud of ultra-cold atoms has been successfully created in space on board of a sounding rocket. The MAIUS mission demonstrates that quantum optical sensors can be operated even in harsh environments like space – a prerequi-site for finding answers to the most challenging questions of fundamental physics and an important innovation driver for everyday applications.
According to Albert Einstein's Equivalence Principle, all bodies are accelerated at the same rate by the Earth's gravity, regardless of their properties. This...
An important step towards a completely new experimental access to quantum physics has been made at University of Konstanz. The team of scientists headed by...
Yersiniae cause severe intestinal infections. Studies using Yersinia pseudotuberculosis as a model organism aim to elucidate the infection mechanisms of these...
Researchers from the University of Hamburg in Germany, in collaboration with colleagues from the University of Aarhus in Denmark, have synthesized a new superconducting material by growing a few layers of an antiferromagnetic transition-metal chalcogenide on a bismuth-based topological insulator, both being non-superconducting materials.
While superconductivity and magnetism are generally believed to be mutually exclusive, surprisingly, in this new material, superconducting correlations...
Laser-driving of semimetals allows creating novel quasiparticle states within condensed matter systems and switching between different states on ultrafast time scales
Studying properties of fundamental particles in condensed matter systems is a promising approach to quantum field theory. Quasiparticles offer the opportunity...
19.01.2017 | Event News
10.01.2017 | Event News
09.01.2017 | Event News
23.01.2017 | Process Engineering
23.01.2017 | Physics and Astronomy
23.01.2017 | Life Sciences