Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Award for a Pioneer of Alzheimer’s Research

04.08.2015

British neuroscientist John Hardy will be awarded this year’s “Hartwig Piepenbrock-DZNE Prize” which is endowed with 60,000 Euro. Piepenbrock and the German Center for Neurodegenerative Diseases (DZNE) herewith honor his seminal contributions to the study of Alzheimer’s disease. The Professor of Neuroscience at University College London (UCL) has made groundbreaking findings on the molecular causes of this brain disorder. His discoveries provide the basis for therapeutic approaches and potential medicines. The award ceremony will take place on World Alzheimer’s Day - September 21, 2015 - in Bonn, Germany.

“John Hardy is a pioneer,“ says Prof. Pierluigi Nicotera, Chairman of the DZNE’s Executive Board. “To him we owe groundbreaking insights into the genetic causes of Alzheimer’s disease and the role of certain proteins for its pathogenesis. Hardy has been involved for more than 25 years in the investigation of Alzheimer’s and shapes this area of research to date. Worldwide, he is one of the most cited Alzheimer’s researchers by scientific journals.”

Arnulf and Olaf Piepenbrock, both Chief Executive Officers and Chairmen of Piepenbrock Group, see in the disease not only a challenge for science but also for society. “In Germany, about 1.5 Million people have dementia. Many of them are affected by Alzheimer’s. We require new approaches in order to help patients and their relatives,” as Olaf Piepenbrock explains the motif for donating the prize money. “Groundbreaking research for possible therapies is the best way to achieve this. With the award we aim at honoring outstanding accomplishments in this field.”

Every two years the “Hartwig Piepenbrock-DZNE Prize” honors outstanding contributions to the study of neurodegenerative diseases. These diseases, which include Alzheimer’s, are characterized by neuronal dysfunctions and the death of nerve cells. The prize is endowed by the Piepenbrock Group. The winner is chosen by an international committee under the coordination of the DZNE.

This year, the prize will be awarded for the third time. In 2013 it went jointly to the Swiss Adriano Aguzzi and the US-American Charles Weissmann, in 2011 the awardee was the German molecular biologist Konrad Beyreuther.

Background on the awardee

John Hardy (born 1954) is Professor of Neuroscience at University College London (UCL) and a Fellow of the Royal Society. He specializes in molecular genetics. Hardy is one of the world’s leading experts on the genetic causes of Alzheimer’s, Parkinson’s and other diseases of the nervous system. For roughly two decades, the British scientist has been giving new momentum to this field of research time and again and continues to do so today. Particularly outstanding is a discovery Hardy made at the beginning of the 1990s: He was the first to find a genetic defect that can trigger Alzheimer’s disease. Today, several such defects are known.

With the discovery of this genetic fault which may occur in the blueprint of the so-called amyloid precursor protein, Hardy laid one of the cornerstones of the “amyloid hypothesis”. This hypothesis assumes that Alzheimer’s is caused by defective proteins – called “amyloids” – that accumulate in the brain thereby damaging the nerve cells.

The amyloid hypothesis is one of the most significant models for explaining the molecular processes underlying Alzheimer’s disease. Moreover, it is the basis for several treatment approaches that aim to prevent an accumulation of defective proteins or to dissolve existing aggregates.

Further Reading
http://www.ucl.ac.uk/rlweston-inst/people/john
http://www.ucl.ac.uk/ukpdc/principal-investigators/john-hardy

The Hartwig Piepenbrock-DZNE Prize is awarded in remembrance of the Group’s former Chief Executive Officer and Chairman of the same name. Hartwig Piepenbrock himself passed away after suffering from dementia. He had been committed to art, science and society for many years.

The German Center for Neurodegenerative Diseases (DZNE) investigates the causes of diseases of the nervous system and develops strategies for prevention, treatment and care. It is an institution of the Helmholtz Association of German Research Centres with sites in Berlin, Bonn, Dresden, Göttingen, Magdeburg, Munich, Rostock/Greifswald, Tübingen and Witten. The DZNE cooperates closely with universities, their clinics and other research facilities. Website: http://www.dzne.de

The Piepenbrock Group is an owner-managed family enterprise in the fourth generation. Piepenbrock relieves and strengthens its customers with a broad attendance range, for example in the business units facility management, cleaning services, maintenance and security services. In the field of mechanical engineering Piepenbrock is successful in producing packaging machines. The company is further known for its high-performance chemical products. Piepenbrock epitomizes sustainable acting. Since 2014, the company has been carrying the seal “ensured sustainability” of the “Deutsches privates Institut für Nachhaltigkeit und Ökonomie”. Website: http://www.piepenbrock.de

Weitere Informationen:

http://www.dzne.de/en/about-us/public-relations/meldungen/2015/press-release-no-...

Dr. Marcus Neitzert | idw - Informationsdienst Wissenschaft

More articles from Awards Funding:

nachricht Otto Hahn Medal for Jaime Agudo-Canalejo
21.06.2017 | Max-Planck-Institut für Kolloid- und Grenzflächenforschung

nachricht Call for nominations of outstanding catalysis researchers for the Otto Roelen Medal 2018
20.06.2017 | DECHEMA Gesellschaft für Chemische Technik und Biotechnologie e.V.

All articles from Awards Funding >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Can we see monkeys from space? Emerging technologies to map biodiversity

An international team of scientists has proposed a new multi-disciplinary approach in which an array of new technologies will allow us to map biodiversity and the risks that wildlife is facing at the scale of whole landscapes. The findings are published in Nature Ecology and Evolution. This international research is led by the Kunming Institute of Zoology from China, University of East Anglia, University of Leicester and the Leibniz Institute for Zoo and Wildlife Research.

Using a combination of satellite and ground data, the team proposes that it is now possible to map biodiversity with an accuracy that has not been previously...

Im Focus: Climate satellite: Tracking methane with robust laser technology

Heatwaves in the Arctic, longer periods of vegetation in Europe, severe floods in West Africa – starting in 2021, scientists want to explore the emissions of the greenhouse gas methane with the German-French satellite MERLIN. This is made possible by a new robust laser system of the Fraunhofer Institute for Laser Technology ILT in Aachen, which achieves unprecedented measurement accuracy.

Methane is primarily the result of the decomposition of organic matter. The gas has a 25 times greater warming potential than carbon dioxide, but is not as...

Im Focus: How protons move through a fuel cell

Hydrogen is regarded as the energy source of the future: It is produced with solar power and can be used to generate heat and electricity in fuel cells. Empa researchers have now succeeded in decoding the movement of hydrogen ions in crystals – a key step towards more efficient energy conversion in the hydrogen industry of tomorrow.

As charge carriers, electrons and ions play the leading role in electrochemical energy storage devices and converters such as batteries and fuel cells. Proton...

Im Focus: A unique data centre for cosmological simulations

Scientists from the Excellence Cluster Universe at the Ludwig-Maximilians-Universität Munich have establised "Cosmowebportal", a unique data centre for cosmological simulations located at the Leibniz Supercomputing Centre (LRZ) of the Bavarian Academy of Sciences. The complete results of a series of large hydrodynamical cosmological simulations are available, with data volumes typically exceeding several hundred terabytes. Scientists worldwide can interactively explore these complex simulations via a web interface and directly access the results.

With current telescopes, scientists can observe our Universe’s galaxies and galaxy clusters and their distribution along an invisible cosmic web. From the...

Im Focus: Scientists develop molecular thermometer for contactless measurement using infrared light

Temperature measurements possible even on the smallest scale / Molecular ruby for use in material sciences, biology, and medicine

Chemists at Johannes Gutenberg University Mainz (JGU) in cooperation with researchers of the German Federal Institute for Materials Research and Testing (BAM)...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Plants are networkers

19.06.2017 | Event News

Digital Survival Training for Executives

13.06.2017 | Event News

Global Learning Council Summit 2017

13.06.2017 | Event News

 
Latest News

Quantum thermometer or optical refrigerator?

23.06.2017 | Physics and Astronomy

A 100-year-old physics problem has been solved at EPFL

23.06.2017 | Physics and Astronomy

Equipping form with function

23.06.2017 | Information Technology

VideoLinks
B2B-VideoLinks
More VideoLinks >>>