British neuroscientist John Hardy will be awarded this year’s “Hartwig Piepenbrock-DZNE Prize” which is endowed with 60,000 Euro. Piepenbrock and the German Center for Neurodegenerative Diseases (DZNE) herewith honor his seminal contributions to the study of Alzheimer’s disease. The Professor of Neuroscience at University College London (UCL) has made groundbreaking findings on the molecular causes of this brain disorder. His discoveries provide the basis for therapeutic approaches and potential medicines. The award ceremony will take place on World Alzheimer’s Day - September 21, 2015 - in Bonn, Germany.
“John Hardy is a pioneer,“ says Prof. Pierluigi Nicotera, Chairman of the DZNE’s Executive Board. “To him we owe groundbreaking insights into the genetic causes of Alzheimer’s disease and the role of certain proteins for its pathogenesis. Hardy has been involved for more than 25 years in the investigation of Alzheimer’s and shapes this area of research to date. Worldwide, he is one of the most cited Alzheimer’s researchers by scientific journals.”
Arnulf and Olaf Piepenbrock, both Chief Executive Officers and Chairmen of Piepenbrock Group, see in the disease not only a challenge for science but also for society. “In Germany, about 1.5 Million people have dementia. Many of them are affected by Alzheimer’s. We require new approaches in order to help patients and their relatives,” as Olaf Piepenbrock explains the motif for donating the prize money. “Groundbreaking research for possible therapies is the best way to achieve this. With the award we aim at honoring outstanding accomplishments in this field.”
Every two years the “Hartwig Piepenbrock-DZNE Prize” honors outstanding contributions to the study of neurodegenerative diseases. These diseases, which include Alzheimer’s, are characterized by neuronal dysfunctions and the death of nerve cells. The prize is endowed by the Piepenbrock Group. The winner is chosen by an international committee under the coordination of the DZNE.
This year, the prize will be awarded for the third time. In 2013 it went jointly to the Swiss Adriano Aguzzi and the US-American Charles Weissmann, in 2011 the awardee was the German molecular biologist Konrad Beyreuther.
Background on the awardee
John Hardy (born 1954) is Professor of Neuroscience at University College London (UCL) and a Fellow of the Royal Society. He specializes in molecular genetics. Hardy is one of the world’s leading experts on the genetic causes of Alzheimer’s, Parkinson’s and other diseases of the nervous system. For roughly two decades, the British scientist has been giving new momentum to this field of research time and again and continues to do so today. Particularly outstanding is a discovery Hardy made at the beginning of the 1990s: He was the first to find a genetic defect that can trigger Alzheimer’s disease. Today, several such defects are known.
With the discovery of this genetic fault which may occur in the blueprint of the so-called amyloid precursor protein, Hardy laid one of the cornerstones of the “amyloid hypothesis”. This hypothesis assumes that Alzheimer’s is caused by defective proteins – called “amyloids” – that accumulate in the brain thereby damaging the nerve cells.
The amyloid hypothesis is one of the most significant models for explaining the molecular processes underlying Alzheimer’s disease. Moreover, it is the basis for several treatment approaches that aim to prevent an accumulation of defective proteins or to dissolve existing aggregates.
The Hartwig Piepenbrock-DZNE Prize is awarded in remembrance of the Group’s former Chief Executive Officer and Chairman of the same name. Hartwig Piepenbrock himself passed away after suffering from dementia. He had been committed to art, science and society for many years.
The German Center for Neurodegenerative Diseases (DZNE) investigates the causes of diseases of the nervous system and develops strategies for prevention, treatment and care. It is an institution of the Helmholtz Association of German Research Centres with sites in Berlin, Bonn, Dresden, Göttingen, Magdeburg, Munich, Rostock/Greifswald, Tübingen and Witten. The DZNE cooperates closely with universities, their clinics and other research facilities. Website: http://www.dzne.de
The Piepenbrock Group is an owner-managed family enterprise in the fourth generation. Piepenbrock relieves and strengthens its customers with a broad attendance range, for example in the business units facility management, cleaning services, maintenance and security services. In the field of mechanical engineering Piepenbrock is successful in producing packaging machines. The company is further known for its high-performance chemical products. Piepenbrock epitomizes sustainable acting. Since 2014, the company has been carrying the seal “ensured sustainability” of the “Deutsches privates Institut für Nachhaltigkeit und Ökonomie”. Website: http://www.piepenbrock.de
Dr. Marcus Neitzert | idw - Informationsdienst Wissenschaft
Changing the Energy Landscape: Affordable Electricity for All
20.10.2016 | Fraunhofer-Institut für Solare Energiesysteme ISE
Emmy Noether junior research group investigates new magnetic structures for spintronics applications
11.10.2016 | Johannes Gutenberg-Universität Mainz
Researchers from the Institute for Quantum Computing (IQC) at the University of Waterloo led the development of a new extensible wiring technique capable of controlling superconducting quantum bits, representing a significant step towards to the realization of a scalable quantum computer.
"The quantum socket is a wiring method that uses three-dimensional wires based on spring-loaded pins to address individual qubits," said Jeremy Béjanin, a PhD...
In a paper in Scientific Reports, a research team at Worcester Polytechnic Institute describes a novel light-activated phenomenon that could become the basis for applications as diverse as microscopic robotic grippers and more efficient solar cells.
A research team at Worcester Polytechnic Institute (WPI) has developed a revolutionary, light-activated semiconductor nanocomposite material that can be used...
By forcefully embedding two silicon atoms in a diamond matrix, Sandia researchers have demonstrated for the first time on a single chip all the components needed to create a quantum bridge to link quantum computers together.
"People have already built small quantum computers," says Sandia researcher Ryan Camacho. "Maybe the first useful one won't be a single giant quantum computer...
COMPAMED has become the leading international marketplace for suppliers of medical manufacturing. The trade fair, which takes place every November and is co-located to MEDICA in Dusseldorf, has been steadily growing over the past years and shows that medical technology remains a rapidly growing market.
In 2016, the joint pavilion by the IVAM Microtechnology Network, the Product Market “High-tech for Medical Devices”, will be located in Hall 8a again and will...
'Ferroelectric' materials can switch between different states of electrical polarization in response to an external electric field. This flexibility means they show promise for many applications, for example in electronic devices and computer memory. Current ferroelectric materials are highly valued for their thermal and chemical stability and rapid electro-mechanical responses, but creating a material that is scalable down to the tiny sizes needed for technologies like silicon-based semiconductors (Si-based CMOS) has proven challenging.
Now, Hiroshi Funakubo and co-workers at the Tokyo Institute of Technology, in collaboration with researchers across Japan, have conducted experiments to...
14.10.2016 | Event News
14.10.2016 | Event News
12.10.2016 | Event News
21.10.2016 | Health and Medicine
21.10.2016 | Information Technology
21.10.2016 | Materials Sciences