The genomic technique, known as TALENS, is described in a report published today in the scientific journal Proceedings of the National Academy of Science. The technique is cheaper and faster than previous technologies that allow scientists to genetically modify livestock animals; the animals are used to learn more about human diseases, which in turn can help researchers develop cures. U of M scientists and their collaborators used the technique to develop a swine model of cardiovascular disease in the diabetes-prone Ossabaw miniature pig.
The TALENS technique also can be used in agriculture, the paper notes, allowing livestock breeders to encourage or discourage a particular trait.
“Our efforts continue a long tradition of responsible animal breeding and research for the betterment of mankind,” said Scott Fahrenkrug, an associate professor of animal science at the university and lead author of the PNAS paper.
Collaborators on the paper are from Texas A&M, the Roslin Institute at the University of Edinburgh and Recombinetics, a Twin Cities-based company created in 2009 to commercialize the techniques created at the University of Minnesota. The group’s work and the TALENS technique also recently were highlighted in the journal Nature.
“This work embodies the effective translation of university research into meaningful applications that support Minnesota business,” Fahrenkrug said. “We are proud to produce positive social and economic outcomes.”
Media Note: The full paper is available online at http://www.pnas.org/.
Matt Hodson, University News Service, email@example.com, (612) 625-0552
Becky Beyers | EurekAlert!
Cascading use is also beneficial for wood
11.12.2017 | Technische Universität München
The future of crop engineering
08.12.2017 | Max-Planck-Institut für Biochemie
MPQ scientists achieve long storage times for photonic quantum bits which break the lower bound for direct teleportation in a global quantum network.
Concerning the development of quantum memories for the realization of global quantum networks, scientists of the Quantum Dynamics Division led by Professor...
Researchers have developed a water cloaking concept based on electromagnetic forces that could eliminate an object's wake, greatly reducing its drag while...
Tiny pores at a cell's entryway act as miniature bouncers, letting in some electrically charged atoms--ions--but blocking others. Operating as exquisitely sensitive filters, these "ion channels" play a critical role in biological functions such as muscle contraction and the firing of brain cells.
To rapidly transport the right ions through the cell membrane, the tiny channels rely on a complex interplay between the ions and surrounding molecules,...
The miniaturization of the current technology of storage media is hindered by fundamental limits of quantum mechanics. A new approach consists in using so-called spin-crossover molecules as the smallest possible storage unit. Similar to normal hard drives, these special molecules can save information via their magnetic state. A research team from Kiel University has now managed to successfully place a new class of spin-crossover molecules onto a surface and to improve the molecule’s storage capacity. The storage density of conventional hard drives could therefore theoretically be increased by more than one hundred fold. The study has been published in the scientific journal Nano Letters.
Over the past few years, the building blocks of storage media have gotten ever smaller. But further miniaturization of the current technology is hindered by...
With innovative experiments, researchers at the Helmholtz-Zentrums Geesthacht and the Technical University Hamburg unravel why tiny metallic structures are extremely strong
Light-weight and simultaneously strong – porous metallic nanomaterials promise interesting applications as, for instance, for future aeroplanes with enhanced...
11.12.2017 | Event News
08.12.2017 | Event News
07.12.2017 | Event News
13.12.2017 | Health and Medicine
13.12.2017 | Physics and Astronomy
13.12.2017 | Life Sciences