In developing countries, half of all young children suffer from anaemia, often as a result of iron-deficiency. The cause is a one-sided diet based mainly on grains. These contain phytates, substances which bind the nutrient iron from plant sources as insoluble salts. As the iron-binding phytates are not broken down in the gastrointestinal tract, the body absorbs only 5% of all the iron in plant food. The rest is excreted by the body.
Iron-deficiency can be combated relatively inexpensively by adding iron to foodstuffs. Maize and wheat are ideal for this; large population groups consume these types of flours in large quantities throughout the year. International efforts (including those of the World Health Organization and Unicef) to reinforce flour with iron are beginning to bear fruit. In 1990 only the United States and Canada reinforced their flour with iron; now 49 countries are doing the same, including Nigeria and South Africa, countries of influence in Africa.
In most countries fortification is by adding almost pure iron powder. This is prepared by treating iron oxides with hydrogen or carbon monoxide at high temperatures, or by a process in which iron is produced electrolytically from iron sulphate. The product is then ground into a very fine powder.
The researchers from Wageningen University and from Unilever suspected, however, that this iron powder would not be effective because it also binds with the phytates. So they used iron that Akzo Nobel had chemically ‘wrapped’ in an organic ‘jacket’ made of the compound EDTA. The iron-EDTA (chemical formula NaFeEDTA.3H2O) protects the iron, so that it is not able to bind with the phytates. The iron 'in a jacket' which is consumed with the food remains bound in the acid conditions in the stomach. It becomes available for absorption by the intestinal cells in less acid conditions, like that of the small intestine.
The researchers put this to the test by comparing electrolytically produced iron with iron in iron-EDTA in a so-called randomised placebo-controlled trial among 516 Kenyan schoolchildren. In this experiment, different groups of children were given porridge made from whole maize flour every day for a period of five months. Electrolytic iron was added to the flour for the first group in amounts according to the requirements of the South African government (56 mg/kg). A second group was given porridge made from flour with an equal amount of ‘jacketed’ iron (iron-EDTA). No iron was added to the flour of the third group of children.
At the end of the experiment, it appeared that fortification with iron-EDTA had reduced the occurrence of iron-deficiency anaemia by 89%, while the electrolytic iron had no effect at all on the prevention of anaemia. As expected, it appeared that the children with an iron deficiency, in particular, gained from the intervention; in contrast, the iron-EDTA had no effect on the children who already had sufficient iron reserves at the beginning of the experiment. The iron intervention did not lead to iron overload because the body regulates the absorption of iron in accordance with its requirements.
The researchers have come to the conclusion that iron-EDTA gives an improved iron status and that this in case of fortification of flours with high phytate contents, as is common in Africa and developing countries elsewhere, is to be preferred to electrolytic iron. It is expected that these findings will lead to amendments to national directives and legislation concerning food fortification in developing countries.
Jac Niessen | alfa
Plasma-zapping process could yield trans fat-free soybean oil product
02.12.2016 | Purdue University
New findings about the deformed wing virus, a major factor in honey bee colony mortality
11.11.2016 | Veterinärmedizinische Universität Wien
In recent years, lasers with ultrashort pulses (USP) down to the femtosecond range have become established on an industrial scale. They could advance some applications with the much-lauded “cold ablation” – if that meant they would then achieve more throughput. A new generation of process engineering that will address this issue in particular will be discussed at the “4th UKP Workshop – Ultrafast Laser Technology” in April 2017.
Even back in the 1990s, scientists were comparing materials processing with nanosecond, picosecond and femtosesecond pulses. The result was surprising:...
Have you ever wondered how you see the world? Vision is about photons of light, which are packets of energy, interacting with the atoms or molecules in what...
A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.
Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...
In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.
“Our Quantum droplets are in the gas phase but they still drop like a rock,” explains experimental physicist Francesca Ferlaino when talking about the...
The Max Planck Institute for Physics (MPP) is opening up a new research field. A workshop from November 21 - 22, 2016 will mark the start of activities for an innovative axion experiment. Axions are still only purely hypothetical particles. Their detection could solve two fundamental problems in particle physics: What dark matter consists of and why it has not yet been possible to directly observe a CP violation for the strong interaction.
The “MADMAX” project is the MPP’s commitment to axion research. Axions are so far only a theoretical prediction and are difficult to detect: on the one hand,...
16.11.2016 | Event News
01.11.2016 | Event News
14.10.2016 | Event News
07.12.2016 | Earth Sciences
07.12.2016 | Earth Sciences
07.12.2016 | Materials Sciences