Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Genetic modification a tool for making vegetables and fruit (even) healthier

09.02.2007
It is possible to improve the antioxidant action of tomatoes by a directed change in the production of flavonoids by means of genetic modification.

This has been shown in research by Elio Schijlen at Plant Research Internationa, part of Wageningen University and Research Centre in the Netherlands. Schijlen demonstrated that this approach enables tomatoes to produce larger amounts of specific flavonoids and to let tomatoes produce flavonoids they cannot produce by nature. On the basis of the research Schijlen obtained HIS his PhD-degree on Thursday 8 February at the University of Amsterdam.

The results of this research show that genetic modification is a possible approach to further increase the health promoting value of vegetables and fruit. Flavonoids are frequently occurring and important metabolites in plants. About 6000 different flavonoids are known to be involved in various natural processes. The colour of flowers and ripe fruits, e.g., are often caused by flavonoids. But flavonoids also play an important role in other plant processes such as pollen production, disease resistance, and protection against UV radiation.

Because flavonoids are so frequently occurring in plants, they are a permanent component of our food. Part of the health promoting effects of vegetables and fruit is attributed to flavonoids. It may therefore be attractive to increase the amount of flavonoids and/or change their composition.

This was why Schijlen, working at Plant Research International of Wageningen UR, studied the possibilities of steering the production of flavonoids by a directed change of the biosynthesis route via genetic modification. He followed various approaches to achieve this. One approach was to investigate the possibility of increasing the amount of flavonoids in tomato by means of so-called transcription factors, proteins involved in regulating gene activity.

Schijlen also investigated the possibility to produce new flavonoids in tomatoes which might increase the health promoting properties of tomatoes. For this purpose he used genes form other crops such as grape and alfalfa, genes that are involved in certain steps in the biosynthesis of flavonoids in these crops.

Both approaches were found to be successful. Through genetic modification Schijlen succeeded in developing tomatoes not only with more flavonoids but also with new flavonoids.

Via biochemical analysis Schijlen demonstrated an increased antioxidant action of tomatoes with flavones and more flavonoles, two specific groups of flavonoids. In cooperation with scientists of BASF Plant Science and TNO, the potential health promoting effects of these tomatoes were tested in feeding studies with mice. Blood analyses showed that that the tomatoes with increased flavonoids had a stronger positive effect on blood properties that are characteristic of a reduced risk of cardiovascular disorders.

With his results, Schijlen has shown that genetic modification can further increase the health promoting effects of vegetables and fruit.

Jac Niessen | alfa
Further information:
http://www.wur.nl

More articles from Agricultural and Forestry Science:

nachricht Six-legged livestock -- sustainable food production
11.05.2017 | Faculty of Science - University of Copenhagen

nachricht Elephant Herpes: Super-Shedders Endanger Young Animals
04.05.2017 | Universität Zürich

All articles from Agricultural and Forestry Science >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Can the immune system be boosted against Staphylococcus aureus by delivery of messenger RNA?

Staphylococcus aureus is a feared pathogen (MRSA, multi-resistant S. aureus) due to frequent resistances against many antibiotics, especially in hospital infections. Researchers at the Paul-Ehrlich-Institut have identified immunological processes that prevent a successful immune response directed against the pathogenic agent. The delivery of bacterial proteins with RNA adjuvant or messenger RNA (mRNA) into immune cells allows the re-direction of the immune response towards an active defense against S. aureus. This could be of significant importance for the development of an effective vaccine. PLOS Pathogens has published these research results online on 25 May 2017.

Staphylococcus aureus (S. aureus) is a bacterium that colonizes by far more than half of the skin and the mucosa of adults, usually without causing infections....

Im Focus: A quantum walk of photons

Physicists from the University of Würzburg are capable of generating identical looking single light particles at the push of a button. Two new studies now demonstrate the potential this method holds.

The quantum computer has fuelled the imagination of scientists for decades: It is based on fundamentally different phenomena than a conventional computer....

Im Focus: Turmoil in sluggish electrons’ existence

An international team of physicists has monitored the scattering behaviour of electrons in a non-conducting material in real-time. Their insights could be beneficial for radiotherapy.

We can refer to electrons in non-conducting materials as ‘sluggish’. Typically, they remain fixed in a location, deep inside an atomic composite. It is hence...

Im Focus: Wafer-thin Magnetic Materials Developed for Future Quantum Technologies

Two-dimensional magnetic structures are regarded as a promising material for new types of data storage, since the magnetic properties of individual molecular building blocks can be investigated and modified. For the first time, researchers have now produced a wafer-thin ferrimagnet, in which molecules with different magnetic centers arrange themselves on a gold surface to form a checkerboard pattern. Scientists at the Swiss Nanoscience Institute at the University of Basel and the Paul Scherrer Institute published their findings in the journal Nature Communications.

Ferrimagnets are composed of two centers which are magnetized at different strengths and point in opposing directions. Two-dimensional, quasi-flat ferrimagnets...

Im Focus: World's thinnest hologram paves path to new 3-D world

Nano-hologram paves way for integration of 3-D holography into everyday electronics

An Australian-Chinese research team has created the world's thinnest hologram, paving the way towards the integration of 3D holography into everyday...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Marine Conservation: IASS Contributes to UN Ocean Conference in New York on 5-9 June

24.05.2017 | Event News

AWK Aachen Machine Tool Colloquium 2017: Internet of Production for Agile Enterprises

23.05.2017 | Event News

Dortmund MST Conference presents Individualized Healthcare Solutions with micro and nanotechnology

22.05.2017 | Event News

 
Latest News

How herpesviruses win the footrace against the immune system

26.05.2017 | Life Sciences

Water forms 'spine of hydration' around DNA, group finds

26.05.2017 | Life Sciences

First Juno science results supported by University of Leicester's Jupiter 'forecast'

26.05.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>