Whether the problem be zoonoses, diseases that may be transmitted from animals to man, or animal diseases that become epidemics, preventive or therapeutic vaccines are a vital alternative. Therapeutic vaccines, developed by molecular biology, are a particularly novel way of treating diseases, and are based on using interfering RNA molecules. Towards the end of 2005, CIRAD developed and patented interfering RNAs that act against the morbilliviruses that cause measles, rinderpest and peste des petits ruminants. Since then, research work has continued with a view to targeting the effect of these biological antivirals in animals.
As Emmanuel Albina* explains, "Unlike chemical molecules, interfering RNA fragments that are only active on the target virus or family of viruses block the virus development process within infected cells." He adds "this strategy completely changes all the concepts of disease control. The choice is no longer limited to eradicating the infected animal population or mass preventive vaccination. A third tool, therapeutic vaccines, could be used on infected animals."
This new biological approach to animal diseases primarily applies to those affecting ruminants (rinderpest, peste des petits ruminants, foot and mouth, etc) and swine - pigs, wild boars - (African swine fever).
Man could also benefit from these new techniques. Measles, a human disease that affects young people in developing countries, belongs to the same virus family as peste des petits ruminants and rinderpest. Pharmaceutical research has also jumped on the bandwagon and is looking to use the same techniques to treat cancer.
* immunology and microbiology researcher with CIRAD
Helen Burford | alfa
New 3-D model predicts best planting practices for farmers
26.06.2017 | Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign
Fighting a destructive crop disease with mathematics
21.06.2017 | University of Cambridge
Physicists have developed a new technique that uses electrical voltages to control the electron spin on a chip. The newly-developed method provides protection from spin decay, meaning that the contained information can be maintained and transmitted over comparatively large distances, as has been demonstrated by a team from the University of Basel’s Department of Physics and the Swiss Nanoscience Institute. The results have been published in Physical Review X.
For several years, researchers have been trying to use the spin of an electron to store and transmit information. The spin of each electron is always coupled...
What is the mass of a proton? Scientists from Germany and Japan successfully did an important step towards the most exact knowledge of this fundamental constant. By means of precision measurements on a single proton, they could improve the precision by a factor of three and also correct the existing value.
To determine the mass of a single proton still more accurate – a group of physicists led by Klaus Blaum and Sven Sturm of the Max Planck Institute for Nuclear...
The research team of Prof. Dr. Oliver Einsle at the University of Freiburg's Institute of Biochemistry has long been exploring the functioning of nitrogenase....
A one trillion tonne iceberg - one of the biggest ever recorded -- has calved away from the Larsen C Ice Shelf in Antarctica, after a rift in the ice,...
Physics supports biology: Researchers from PTB have developed a model system to investigate friction phenomena with atomic precision
Friction: what you want from car brakes, otherwise rather a nuisance. In any case, it is useful to know as precisely as possible how friction phenomena arise –...
21.07.2017 | Event News
19.07.2017 | Event News
12.07.2017 | Event News
21.07.2017 | Earth Sciences
21.07.2017 | Power and Electrical Engineering
21.07.2017 | Physics and Astronomy