Scientists from Novosibirsk are engaged in the development of an unusual vaccine which, apart from being less expensive to produce, safe and painless to administer, is also edible. The research is being accomplished in the framework of the ISTC Partner Project #2176, which is funded by the Agricultural Research Service of the U.S. Department of Agriculture, and so far the project team has managed to introduce a HIV antigen protein gene into tomatoes.
Usually, vaccines are injected, but some - like the polio vaccine - can be ingested or eaten. Thus, a number of years ago plant genetic engineers started producing vaccine proteins in plants to test their effectiveness, which started a whole new area of plant derived edible vaccines. This approach has already been used to test vaccines for hepatitis viruses and some bacterial pathogens, but Dr. Sergey Shchelkunov at SRC of Virology and Biotechnology "Vector" wondered if an edible vaccine for HIV AIDS could be produced.
Dr. Shchelkunovs laboratory teamed up with other Russian scientists from both the Novosibirsk Institute of Biological Chemistry and Basic Medicine, and the Siberian Institute of Plant Physiology and Biochemistry in Irkutsk, Russia. A functional vaccine from their work is still to be tested, but as a result of project 2176 the researchers were able to insert into the chromosome of tomato plants a gene from HIV. Furthermore, they were able to show that the corresponding protein product from the HIV gene was expressed in different parts of the transgenic tomato plant including ripe fruit. And, because this is a vaccine based on a single protein from HIV, there is no risk of acquiring an HIV infection from eating the tomato fruit.
Alexander Ivanchenko | alfa
Raiding the rape field
23.05.2018 | Julius-Maximilians-Universität Würzburg
New technique reveals details of forest fire recovery
17.05.2018 | DOE/Brookhaven National Laboratory
The more electronics steer, accelerate and brake cars, the more important it is to protect them against cyber-attacks. That is why 15 partners from industry and academia will work together over the next three years on new approaches to IT security in self-driving cars. The joint project goes by the name Security For Connected, Autonomous Cars (SecForCARs) and has funding of €7.2 million from the German Federal Ministry of Education and Research. Infineon is leading the project.
Vehicles already offer diverse communication interfaces and more and more automated functions, such as distance and lane-keeping assist systems. At the same...
A research team led by physicists at the Technical University of Munich (TUM) has developed molecular nanoswitches that can be toggled between two structurally different states using an applied voltage. They can serve as the basis for a pioneering class of devices that could replace silicon-based components with organic molecules.
The development of new electronic technologies drives the incessant reduction of functional component sizes. In the context of an international collaborative...
At the LASYS 2018, from June 5th to 7th, the Laser Zentrum Hannover e.V. (LZH) will be showcasing processes for the laser material processing of tomorrow in hall 4 at stand 4E75. With blown bomb shells the LZH will present first results of a research project on civil security.
At this year's LASYS, the LZH will exhibit light-based processes such as cutting, welding, ablation and structuring as well as additive manufacturing for...
There are videos on the internet that can make one marvel at technology. For example, a smartphone is casually bent around the arm or a thin-film display is rolled in all directions and with almost every diameter. From the user's point of view, this looks fantastic. From a professional point of view, however, the question arises: Is that already possible?
At Display Week 2018, scientists from the Fraunhofer Institute for Applied Polymer Research IAP will be demonstrating today’s technological possibilities and...
So-called quantum many-body scars allow quantum systems to stay out of equilibrium much longer, explaining experiment | Study published in Nature Physics
Recently, researchers from Harvard and MIT succeeded in trapping a record 53 atoms and individually controlling their quantum state, realizing what is called a...
25.05.2018 | Event News
02.05.2018 | Event News
13.04.2018 | Event News
25.05.2018 | Event News
25.05.2018 | Machine Engineering
25.05.2018 | Life Sciences