Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Fighting sheep worms with genomics

18.05.2004


Leading-edge technology is being used by two CSIRO Livestock Industries’ research teams to identify genes that enable sheep to resist intestinal parasites.

The discovery of such genes could lead to new products, control strategies, and markers to identify superior animals in selective breeding programs, which will substantially improve the overall health and welfare of the national flock.

With support from Meat and Livestock Australia (MLA) and Australian Wool Innovation (AWI) through their joint $30m Sheep Genomics Program, the Brisbane and Armidale-based teams will use modern genetic technologies - such as microarrays and the real-time polymerase chain reaction (PCR) - to determine the expression level of genes in worm-resistant and susceptible sheep.



"CSIRO Livestock Industries in Armidale has a long history of research into resistance to nematodes (worms), and has selectively bred nematode-resistant flocks of sheep that facilitate both projects," says Brisbane team leader, Dr Aaron Ingham.

"The Brisbane and Armidale teams will work closely together to conduct detailed complementary molecular genetic analyses on sheep produced from these flocks. The Armidale team will also provide the necessary parasitological and immunological expertise for both projects," he says.

The Brisbane team will use real time PCR to screen a number of ’candidate’ genes that are known to be involved in disease responsiveness and resistance, tissue regeneration, wound repair, appetite and basic physiology.

The Armidale team will use microarray technology to undertake a broad, unbiased screen of thousands of genes, to identify those responsible for nematode resistance.

Gene expression that is consistently different between resistant and susceptible animals will be targeted for further study.

More information:

Dr Aaron Ingham, CSIRO Livestock Industries, 07 3214 2663
Dr Ross Windon, CSIRO Livestock Industries, 02 6776 1446
Dr Andrew Parratt, AWI, 0418 861 153
Hutton Oddy, MLA, 02 9463 9228

Media assistance:
Veronica Toohey, 07 3214 2960
Rob Nethery, 02 6776 1389

Bill Stephens | CSIRO
Further information:
http://www.csiro.au/index.asp?type=mediaRelease&id=Prsheepworms

More articles from Agricultural and Forestry Science:

nachricht Faba fix for corn's nitrogen need
11.04.2018 | American Society of Agronomy

nachricht Wheat research discovery yields genetic secrets that could shape future crops
09.04.2018 | John Innes Centre

All articles from Agricultural and Forestry Science >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Spider silk key to new bone-fixing composite

University of Connecticut researchers have created a biodegradable composite made of silk fibers that can be used to repair broken load-bearing bones without the complications sometimes presented by other materials.

Repairing major load-bearing bones such as those in the leg can be a long and uncomfortable process.

Im Focus: Writing and deleting magnets with lasers

Study published in the journal ACS Applied Materials & Interfaces is the outcome of an international effort that included teams from Dresden and Berlin in Germany, and the US.

Scientists at the Helmholtz-Zentrum Dresden-Rossendorf (HZDR) together with colleagues from the Helmholtz-Zentrum Berlin (HZB) and the University of Virginia...

Im Focus: Gamma-ray flashes from plasma filaments

Novel highly efficient and brilliant gamma-ray source: Based on model calculations, physicists of the Max PIanck Institute for Nuclear Physics in Heidelberg propose a novel method for an efficient high-brilliance gamma-ray source. A giant collimated gamma-ray pulse is generated from the interaction of a dense ultra-relativistic electron beam with a thin solid conductor. Energetic gamma-rays are copiously produced as the electron beam splits into filaments while propagating across the conductor. The resulting gamma-ray energy and flux enable novel experiments in nuclear and fundamental physics.

The typical wavelength of light interacting with an object of the microcosm scales with the size of this object. For atoms, this ranges from visible light to...

Im Focus: Basel researchers succeed in cultivating cartilage from stem cells

Stable joint cartilage can be produced from adult stem cells originating from bone marrow. This is made possible by inducing specific molecular processes occurring during embryonic cartilage formation, as researchers from the University and University Hospital of Basel report in the scientific journal PNAS.

Certain mesenchymal stem/stromal cells from the bone marrow of adults are considered extremely promising for skeletal tissue regeneration. These adult stem...

Im Focus: Like a wedge in a hinge

Researchers lay groundwork to tailor drugs for new targets in cancer therapy

In the fight against cancer, scientists are developing new drugs to hit tumor cells at so far unused weak points. Such a “sore spot” is the protein complex...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Invitation to the upcoming "Current Topics in Bioinformatics: Big Data in Genomics and Medicine"

13.04.2018 | Event News

Unique scope of UV LED technologies and applications presented in Berlin: ICULTA-2018

12.04.2018 | Event News

IWOLIA: A conference bringing together German Industrie 4.0 and French Industrie du Futur

09.04.2018 | Event News

 
Latest News

Atoms may hum a tune from grand cosmic symphony

20.04.2018 | Physics and Astronomy

New research could literally squeeze more power out of solar cells

20.04.2018 | Physics and Astronomy

New record on squeezing light to one atom: Atomic Lego guides light below one nanometer

20.04.2018 | Physics and Astronomy

VideoLinks
Science & Research
Overview of more VideoLinks >>>