Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

New insights into bog asphodel poisoning of ruminants

17.03.2008
For her doctoral degree, Helene Wisløff classified the toxins found in the bog asphodel plant (Narthecium ossifragum) and investigated the effects of these toxins on kidney cell cultures and on goats and sheep. Bog asphodel poisoning is the single most serious cause of economic loss from plant poisoning among domestic animals in Norway.

Bog asphodel poisoning produces two different diseases. The first of these is elf fire, which affects lambs that graze on bog asphodel. These lambs incur liver damage leading to the accumulation in the blood of substances that make the animals overly sensitive to sunlight.

Some flocks in the west of Norway have been known to lose up to 30 - 50% of their lambs to this condition. Steroidal saponins, one of the toxic groups of the bog asphodel, are thought to be the source of the liver injuries seen in elf fire. The second form of bog asphodel poisoning is acute kidney failure, which is seen sporadically in cattle and moose.

Wisløff's work primarily addressed the disease of acute kidney failure. Lambs with elf fire suffer transient kidney damage of the same type seen in cattle and moose that graze on bog asphodel.

The short-lived kidney injuries seen in lambs are, however, milder and are thought to be caused by a furanone (3-methoxy-2(5H)-furanone). Testing of this substance on kidney cells produced, however, unclear results. Helene Wisløff described therefore other toxins from the bog asphodel and discovered that steroidal saponins had the greatest toxic effect on the kidney cells. Another furanone (5-hydroxy-4-methoxy-2(5H)-furanone) produced more moderate damage.

In one experiment in which lambs received a commercial dietary supplement containing the same saponins as those of bog asphodel, several of the lambs developed acute kidney failure. Saponins were found in the kidney and liver tissues from these lambs.

It was previously thought that saponins from the plants were almost completely converted to sapogenines and sugars in the rumen (one of the stomachs). However, the saponins found in the lamb kidneys were of the same type as those of the plant, that is, they had not been modified. At present it is not known whether the saponins from the bog asphodel can cause kidney damage in ruminants under natural conditions.

Helene Wisløff defended her thesis entitled "Toxic effects of Narthecium ossifragum with emphasis on kidney lesions", for the degree of Dr. med. vet. at the Norwegian School of Veterinary Science, on March 13, 2008.

Magnhild Jenssen | alfa
Further information:
http://www.vetinst.no
http://www.veths.no/105/English/7899/New-insights-into-bog-asphodel-poisoning-of-ruminants/

More articles from Agricultural and Forestry Science:

nachricht Raiding the rape field
23.05.2018 | Julius-Maximilians-Universität Würzburg

nachricht New technique reveals details of forest fire recovery
17.05.2018 | DOE/Brookhaven National Laboratory

All articles from Agricultural and Forestry Science >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: LZH showcases laser material processing of tomorrow at the LASYS 2018

At the LASYS 2018, from June 5th to 7th, the Laser Zentrum Hannover e.V. (LZH) will be showcasing processes for the laser material processing of tomorrow in hall 4 at stand 4E75. With blown bomb shells the LZH will present first results of a research project on civil security.

At this year's LASYS, the LZH will exhibit light-based processes such as cutting, welding, ablation and structuring as well as additive manufacturing for...

Im Focus: Self-illuminating pixels for a new display generation

There are videos on the internet that can make one marvel at technology. For example, a smartphone is casually bent around the arm or a thin-film display is rolled in all directions and with almost every diameter. From the user's point of view, this looks fantastic. From a professional point of view, however, the question arises: Is that already possible?

At Display Week 2018, scientists from the Fraunhofer Institute for Applied Polymer Research IAP will be demonstrating today’s technological possibilities and...

Im Focus: Explanation for puzzling quantum oscillations has been found

So-called quantum many-body scars allow quantum systems to stay out of equilibrium much longer, explaining experiment | Study published in Nature Physics

Recently, researchers from Harvard and MIT succeeded in trapping a record 53 atoms and individually controlling their quantum state, realizing what is called a...

Im Focus: Dozens of binaries from Milky Way's globular clusters could be detectable by LISA

Next-generation gravitational wave detector in space will complement LIGO on Earth

The historic first detection of gravitational waves from colliding black holes far outside our galaxy opened a new window to understanding the universe. A...

Im Focus: Entangled atoms shine in unison

A team led by Austrian experimental physicist Rainer Blatt has succeeded in characterizing the quantum entanglement of two spatially separated atoms by observing their light emission. This fundamental demonstration could lead to the development of highly sensitive optical gradiometers for the precise measurement of the gravitational field or the earth's magnetic field.

The age of quantum technology has long been heralded. Decades of research into the quantum world have led to the development of methods that make it possible...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Save the date: Forum European Neuroscience – 07-11 July 2018 in Berlin, Germany

02.05.2018 | Event News

Invitation to the upcoming "Current Topics in Bioinformatics: Big Data in Genomics and Medicine"

13.04.2018 | Event News

Unique scope of UV LED technologies and applications presented in Berlin: ICULTA-2018

12.04.2018 | Event News

 
Latest News

Research reveals how order first appears in liquid crystals

23.05.2018 | Life Sciences

Space-like gravity weakens biochemical signals in muscle formation

23.05.2018 | Life Sciences

NIST puts the optical microscope under the microscope to achieve atomic accuracy

23.05.2018 | Physics and Astronomy

VideoLinks
Science & Research
Overview of more VideoLinks >>>