Dr. Siddhartha Thakur, assistant professor of population health and pathobiology, had previously found that antibiotic-resistant C. coli, a leading cause of foodborne illness in the U.S., was present in both ABF-certified and conventionally raised pigs.
The pathogen was present in both groups in all facilities from breeding to processing. Thakur wanted to determine whether the C. coli that he found in each group was genetically the same, in order to see if the presence or absence of antimicrobial usage had an effect on the pathogen’s genetic makeup.
The rise of antibiotic-resistant pathogens like C. coli is a concern for the food animal industry. Some pig farms have switched to raising ABF pigs in an attempt to get away from the conditions that facilitated antibiotic resistance in the first place. The hope is that once the selection pressure – in the form of antimicrobial use – on C. coli to retain antibiotic resistance decreases, the pathogen will lose its resistance.
Over several years, Thakur and Ph.D. student Macarena Quintana-Hayashi collected thousands of samples from pigs and their surrounding environments, and performed a genetic analysis on 200 representative isolates of C. coli, to see if these strains were similar. They found that the Campylobacter populations in the two swine production systems (conventional and ABF) were in fact the same. Since the different pig populations never came into contact, the researchers concluded that the environment must be playing a large role in the continuing survival of antibiotic-resistant C. coli.
Thakur’s findings appear online in PLoS One.
“In the case of ABF pigs, the environment plays an important role in their exposure to these resistant strains,” Thakur says. “If the environment itself, and not the pig, is serving as a reservoir for C. coli, then we will most probably continue to find resistant bacterial populations, regardless of a producer’s antimicrobial use.”
Note to editors: Abstract follows.
“Phylogenetic Analysis Reveals Common Antimicrobial Resistant Campylobacter coli Population in Antimicrobial-Free (ABF) and Commercial Swine Systems”
Authors: Macarena P. Quintana-Hayashi, Siddhartha Thakur, North Carolina State University
Published: PLOS OneAbstract:
Tracey Peake | EurekAlert!
Six-legged livestock -- sustainable food production
11.05.2017 | Faculty of Science - University of Copenhagen
Elephant Herpes: Super-Shedders Endanger Young Animals
04.05.2017 | Universität Zürich
The world's highest gain high power laser amplifier - by many orders of magnitude - has been developed in research led at the University of Strathclyde.
The researchers demonstrated the feasibility of using plasma to amplify short laser pulses of picojoule-level energy up to 100 millijoules, which is a 'gain'...
Staphylococcus aureus is a feared pathogen (MRSA, multi-resistant S. aureus) due to frequent resistances against many antibiotics, especially in hospital infections. Researchers at the Paul-Ehrlich-Institut have identified immunological processes that prevent a successful immune response directed against the pathogenic agent. The delivery of bacterial proteins with RNA adjuvant or messenger RNA (mRNA) into immune cells allows the re-direction of the immune response towards an active defense against S. aureus. This could be of significant importance for the development of an effective vaccine. PLOS Pathogens has published these research results online on 25 May 2017.
Staphylococcus aureus (S. aureus) is a bacterium that colonizes by far more than half of the skin and the mucosa of adults, usually without causing infections....
Physicists from the University of Würzburg are capable of generating identical looking single light particles at the push of a button. Two new studies now demonstrate the potential this method holds.
The quantum computer has fuelled the imagination of scientists for decades: It is based on fundamentally different phenomena than a conventional computer....
An international team of physicists has monitored the scattering behaviour of electrons in a non-conducting material in real-time. Their insights could be beneficial for radiotherapy.
We can refer to electrons in non-conducting materials as ‘sluggish’. Typically, they remain fixed in a location, deep inside an atomic composite. It is hence...
Two-dimensional magnetic structures are regarded as a promising material for new types of data storage, since the magnetic properties of individual molecular building blocks can be investigated and modified. For the first time, researchers have now produced a wafer-thin ferrimagnet, in which molecules with different magnetic centers arrange themselves on a gold surface to form a checkerboard pattern. Scientists at the Swiss Nanoscience Institute at the University of Basel and the Paul Scherrer Institute published their findings in the journal Nature Communications.
Ferrimagnets are composed of two centers which are magnetized at different strengths and point in opposing directions. Two-dimensional, quasi-flat ferrimagnets...
24.05.2017 | Event News
23.05.2017 | Event News
22.05.2017 | Event News
29.05.2017 | Earth Sciences
29.05.2017 | Life Sciences
29.05.2017 | Physics and Astronomy