Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

How an aggressive fungal pathogen causes mold in fruits and vegetables

04.10.2013
UC Riverside-led team describes the strategy by which Botrytis cinerea blocks the defense system of its host plants

A research team led by a molecular plant pathologist at the University of California, Riverside has discovered the mechanism by which an aggressive fungal pathogen infects almost all fruits and vegetables.

The team discovered a novel "virulence mechanism" — the mechanism by which infection takes place — of Botrytis cinerea. This pathogen can infect more than 200 plant species, causing serious gray mold disease on almost all fruits and vegetables that have been around, even at times in the refrigerator, for more than a week.

Study results appear in the Oct. 4 issue of the journal Science.

Many bacterial, fungal and oomycete pathogens deliver protein effectors — molecules the pathogens secrete — into the cells of hosts to manipulate and, eventually, compromise host immunity.

The new study represents the first example of a fungal pathogen delivering RNA effectors, specifically small RNA effector molecules, into host cells to suppress host immunity and achieve infection of the host plant.

"To date, almost all the pathogen effectors studied or discovered have been proteins," said lead author Hailing Jin, a professor of plant pathology and microbiology. "Ours is the first study to add the RNA molecule to the list of effectors. We expect our work will help in the development of new means to control aggressive pathogens."

Small RNAs guide gene silencing in a wide range of eukaryotic organisms. In the case of Botrytis cinerea, small RNAs silence the expression of host defense genes, resulting in the host plant cells being less able to resist the fungal attack. The process is similar to how protein effectors weaken host immunity in the case of most pathogens.

"What we have discovered is a naturally-occurring cross-kingdom RNAi phenomenon between a fungal pathogen and a plant host that serves as an advanced virulence mechanism," Jin said.

RNA interference or RNAi is a conserved gene regulatory mechanism that is guided by small RNAs for silencing (or suppressing) genes.

Next, Jin and colleagues plan to continue investigating if the novel mechanism they discovered also exists in other aggressive pathogens.

Jin was joined in the research by UC Riverside's Arne Weiberg, Ming Wang, Hongwei Zhao, Zhihong Zhang and Isgouhi Kaloshian; and Feng-Mao Lin and Hsien-Da Huang at the National Chiao Tung University, Taiwan.

Jin was supported in this research by grants from the National Institutes of Health and the National Science Foundation.

UCR's Office of Technology Commercialization has filed a provisional patent on the research.

The University of California, Riverside (http://www.ucr.edu) is a doctoral research university, a living laboratory for groundbreaking exploration of issues critical to Inland Southern California, the state and communities around the world. Reflecting California's diverse culture, UCR's enrollment has exceeded 21,000 students. The campus will open a medical school in 2013 and has reached the heart of the Coachella Valley by way of the UCR Palm Desert Center. The campus has an annual statewide economic impact of more than $1 billion. A broadcast studio with fiber cable to the AT&T Hollywood hub is available for live or taped interviews. UCR also has ISDN for radio interviews. To learn more, call (951) UCR-NEWS.

Iqbal Pittalwala | EurekAlert!
Further information:
http://www.ucr.edu

Further reports about: Botrytis cinerea RNA RNAi fruits and vegetables fungal pathogen plant cell small RNA

More articles from Agricultural and Forestry Science:

nachricht Raiding the rape field
23.05.2018 | Julius-Maximilians-Universität Würzburg

nachricht New technique reveals details of forest fire recovery
17.05.2018 | DOE/Brookhaven National Laboratory

All articles from Agricultural and Forestry Science >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Molecular switch will facilitate the development of pioneering electro-optical devices

A research team led by physicists at the Technical University of Munich (TUM) has developed molecular nanoswitches that can be toggled between two structurally different states using an applied voltage. They can serve as the basis for a pioneering class of devices that could replace silicon-based components with organic molecules.

The development of new electronic technologies drives the incessant reduction of functional component sizes. In the context of an international collaborative...

Im Focus: LZH showcases laser material processing of tomorrow at the LASYS 2018

At the LASYS 2018, from June 5th to 7th, the Laser Zentrum Hannover e.V. (LZH) will be showcasing processes for the laser material processing of tomorrow in hall 4 at stand 4E75. With blown bomb shells the LZH will present first results of a research project on civil security.

At this year's LASYS, the LZH will exhibit light-based processes such as cutting, welding, ablation and structuring as well as additive manufacturing for...

Im Focus: Self-illuminating pixels for a new display generation

There are videos on the internet that can make one marvel at technology. For example, a smartphone is casually bent around the arm or a thin-film display is rolled in all directions and with almost every diameter. From the user's point of view, this looks fantastic. From a professional point of view, however, the question arises: Is that already possible?

At Display Week 2018, scientists from the Fraunhofer Institute for Applied Polymer Research IAP will be demonstrating today’s technological possibilities and...

Im Focus: Explanation for puzzling quantum oscillations has been found

So-called quantum many-body scars allow quantum systems to stay out of equilibrium much longer, explaining experiment | Study published in Nature Physics

Recently, researchers from Harvard and MIT succeeded in trapping a record 53 atoms and individually controlling their quantum state, realizing what is called a...

Im Focus: Dozens of binaries from Milky Way's globular clusters could be detectable by LISA

Next-generation gravitational wave detector in space will complement LIGO on Earth

The historic first detection of gravitational waves from colliding black holes far outside our galaxy opened a new window to understanding the universe. A...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Save the date: Forum European Neuroscience – 07-11 July 2018 in Berlin, Germany

02.05.2018 | Event News

Invitation to the upcoming "Current Topics in Bioinformatics: Big Data in Genomics and Medicine"

13.04.2018 | Event News

Unique scope of UV LED technologies and applications presented in Berlin: ICULTA-2018

12.04.2018 | Event News

 
Latest News

When corals eat plastics

24.05.2018 | Ecology, The Environment and Conservation

Surgery involving ultrasound energy found to treat high blood pressure

24.05.2018 | Medical Engineering

First chip-scale broadband optical system that can sense molecules in the mid-IR

24.05.2018 | Physics and Astronomy

VideoLinks
Science & Research
Overview of more VideoLinks >>>