Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Researchers in Mainz develop germ reducing implants

13.01.2011
Innovative materials will prevent the development of germs on implants. First product applications will be developed soon.

Mainz. Scientists at the Max Planck Institute for Polymer Research (MPI-P) develop materials that will considerably reduce the risk of inflammations after operations or in wounds. To this end, the scientists work in cooperation with nine other research centers and industrial partners from Spain, Great-Britain, Switzerland and Germany in the EMBEK1 project. The project is designed for three years and is funded with 2.8 Million Euro by the European Union.

Reducing the risk of wound infections

“We are developing surface coatings for implants and dressing material on which the development of germs is hardly possible”, explains Dr. Renate Förch, researcher and project leader at the MPI-P.

“Our special interest lies on the reduction of the complex germs Staphylococcus aureus and Pseudomonas aeroginosa which pose problems in hospitals because they develop antibiotic resistance. The Federal Office of Consumer Protection and Food Safety (BVL) declared in a report that in 2010 already 25 percent of all bacterial strains show antibiotic resistance.

With the help of the methods developed at the MPI-P bacterial infections can be prevented after surgical intervention. To this end, the scientists first have to identify and research both the biological mechanisms underlying the adhesion of germs on certain surfaces and the genetic sequences determining the adhesion process.

“In order to accomplish this, we use the so-called plasma coating of surfaces”, Förch explains. The method used at the MPI for Polymer Research allows for a coating of surfaces with plastic-like materials (plasma polymers) and zinc-releasing materials. Germs can neither adhere to these surfaces nor reproduce themselves.

A cooperative research team from Bath in Great-Britain specialized on the development of an alternative solution to the problem based on metal organometallic hydrogels. Another research group – the Swiss Federal Laboratories for Materials Science and Technology (EMPA) – focuses their research work on the development of nanostructures that can store and release silver using plasma technology. All these approaches have one thing in common: The researchers always have to take into consideration such criteria as the biocompatibility, storage stability and durability. Thus, the biomedical properties of the materials are being examined by research teams of the Institute for forensic medicine of the University Hospital of Cologne, the Exeter University (UK), Consejo Superio de Investigaciones Cientificas in Barcelona (Spain) and the University Medical Center in Mainz.

Good perspectives for innovative product applications

All involved research teams will meet on January 17th and 18th, 2011 in Cologne to exchange interim results of the last two and a half years’ work. Research results from the EMBEK1 project are already being developed further in a follow-up project: The project BacterioSafe is likewise funded with 3.4 Million Euro by the European Union. The project aims at developing materials at the MPI-P that will at the same time be able to release antibiotic agents on dressing materials and indicate the presence of pathogenic germs. In this process, the scientists first have to identify certain biological mechanisms of pathogenic germs. Those mechanisms will then trigger the release of antibacterial agents and colorants as signaling substances for pathogenic germs using nanocapsules and nanovesicles. Renate Förch believes that after the successful conclusion of the EMBEK1project in summer of 2011 and the BacterioSafe project in three and a half years, the first innovative product applications will soon be produced. Förch is managing editor of the scientific journal „Plasma Processes and Polymers“ of the Wiley-VCH publishing house in Weinheim and project leader of a research group at the MPI-P. Together with 10 other scientists she carries out fundamental research on plasma polymerization for biomedical applications. Förch came to the institute in 1996 after having started her scientific career in England and Canada and having worked for the “Institut für Mikrotechnik” (IMM) in Mainz since 1992.

For further information on the EMBEK1 project see:
http://www.mpip-mainz.mpg.de/eu-projekte/embek1/
For further information on the BacterioSafe project see:
http://www.mpip-mainz.mpg.de/eu-projekte/bacteriosafe/

Stephan Imhof | Max-Planck-Institut
Further information:
http://www.mpip-mainz.mpg.de/eu-projekte/bacteriosafe/
http://www.mpip-mainz.mpg.de/eu-projekte/embek1/

More articles from Materials Sciences:

nachricht Switched-on DNA
20.02.2017 | Arizona State University

nachricht Using a simple, scalable method, a material that can be used as a sensor is developed
15.02.2017 | University of the Basque Country

All articles from Materials Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Breakthrough with a chain of gold atoms

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

Im Focus: DNA repair: a new letter in the cell alphabet

Results reveal how discoveries may be hidden in scientific “blind spots”

Cells need to repair damaged DNA in our genes to prevent the development of cancer and other diseases. Our cells therefore activate and send “repair-proteins”...

Im Focus: Dresdner scientists print tomorrow’s world

The Fraunhofer IWS Dresden and Technische Universität Dresden inaugurated their jointly operated Center for Additive Manufacturing Dresden (AMCD) with a festive ceremony on February 7, 2017. Scientists from various disciplines perform research on materials, additive manufacturing processes and innovative technologies, which build up components in a layer by layer process. This technology opens up new horizons for component design and combinations of functions. For example during fabrication, electrical conductors and sensors are already able to be additively manufactured into components. They provide information about stress conditions of a product during operation.

The 3D-printing technology, or additive manufacturing as it is often called, has long made the step out of scientific research laboratories into industrial...

Im Focus: Mimicking nature's cellular architectures via 3-D printing

Research offers new level of control over the structure of 3-D printed materials

Nature does amazing things with limited design materials. Grass, for example, can support its own weight, resist strong wind loads, and recover after being...

Im Focus: Three Magnetic States for Each Hole

Nanometer-scale magnetic perforated grids could create new possibilities for computing. Together with international colleagues, scientists from the Helmholtz Zentrum Dresden-Rossendorf (HZDR) have shown how a cobalt grid can be reliably programmed at room temperature. In addition they discovered that for every hole ("antidot") three magnetic states can be configured. The results have been published in the journal "Scientific Reports".

Physicist Dr. Rantej Bali from the HZDR, together with scientists from Singapore and Australia, designed a special grid structure in a thin layer of cobalt in...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Booth and panel discussion – The Lindau Nobel Laureate Meetings at the AAAS 2017 Annual Meeting

13.02.2017 | Event News

Complex Loading versus Hidden Reserves

10.02.2017 | Event News

International Conference on Crystal Growth in Freiburg

09.02.2017 | Event News

 
Latest News

Switched-on DNA

20.02.2017 | Materials Sciences

Second cause of hidden hearing loss identified

20.02.2017 | Health and Medicine

Prospect for more effective treatment of nerve pain

20.02.2017 | Health and Medicine

VideoLinks
B2B-VideoLinks
More VideoLinks >>>