Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Researchers in Mainz develop germ reducing implants

13.01.2011
Innovative materials will prevent the development of germs on implants. First product applications will be developed soon.

Mainz. Scientists at the Max Planck Institute for Polymer Research (MPI-P) develop materials that will considerably reduce the risk of inflammations after operations or in wounds. To this end, the scientists work in cooperation with nine other research centers and industrial partners from Spain, Great-Britain, Switzerland and Germany in the EMBEK1 project. The project is designed for three years and is funded with 2.8 Million Euro by the European Union.

Reducing the risk of wound infections

“We are developing surface coatings for implants and dressing material on which the development of germs is hardly possible”, explains Dr. Renate Förch, researcher and project leader at the MPI-P.

“Our special interest lies on the reduction of the complex germs Staphylococcus aureus and Pseudomonas aeroginosa which pose problems in hospitals because they develop antibiotic resistance. The Federal Office of Consumer Protection and Food Safety (BVL) declared in a report that in 2010 already 25 percent of all bacterial strains show antibiotic resistance.

With the help of the methods developed at the MPI-P bacterial infections can be prevented after surgical intervention. To this end, the scientists first have to identify and research both the biological mechanisms underlying the adhesion of germs on certain surfaces and the genetic sequences determining the adhesion process.

“In order to accomplish this, we use the so-called plasma coating of surfaces”, Förch explains. The method used at the MPI for Polymer Research allows for a coating of surfaces with plastic-like materials (plasma polymers) and zinc-releasing materials. Germs can neither adhere to these surfaces nor reproduce themselves.

A cooperative research team from Bath in Great-Britain specialized on the development of an alternative solution to the problem based on metal organometallic hydrogels. Another research group – the Swiss Federal Laboratories for Materials Science and Technology (EMPA) – focuses their research work on the development of nanostructures that can store and release silver using plasma technology. All these approaches have one thing in common: The researchers always have to take into consideration such criteria as the biocompatibility, storage stability and durability. Thus, the biomedical properties of the materials are being examined by research teams of the Institute for forensic medicine of the University Hospital of Cologne, the Exeter University (UK), Consejo Superio de Investigaciones Cientificas in Barcelona (Spain) and the University Medical Center in Mainz.

Good perspectives for innovative product applications

All involved research teams will meet on January 17th and 18th, 2011 in Cologne to exchange interim results of the last two and a half years’ work. Research results from the EMBEK1 project are already being developed further in a follow-up project: The project BacterioSafe is likewise funded with 3.4 Million Euro by the European Union. The project aims at developing materials at the MPI-P that will at the same time be able to release antibiotic agents on dressing materials and indicate the presence of pathogenic germs. In this process, the scientists first have to identify certain biological mechanisms of pathogenic germs. Those mechanisms will then trigger the release of antibacterial agents and colorants as signaling substances for pathogenic germs using nanocapsules and nanovesicles. Renate Förch believes that after the successful conclusion of the EMBEK1project in summer of 2011 and the BacterioSafe project in three and a half years, the first innovative product applications will soon be produced. Förch is managing editor of the scientific journal „Plasma Processes and Polymers“ of the Wiley-VCH publishing house in Weinheim and project leader of a research group at the MPI-P. Together with 10 other scientists she carries out fundamental research on plasma polymerization for biomedical applications. Förch came to the institute in 1996 after having started her scientific career in England and Canada and having worked for the “Institut für Mikrotechnik” (IMM) in Mainz since 1992.

For further information on the EMBEK1 project see:
http://www.mpip-mainz.mpg.de/eu-projekte/embek1/
For further information on the BacterioSafe project see:
http://www.mpip-mainz.mpg.de/eu-projekte/bacteriosafe/

Stephan Imhof | Max-Planck-Institut
Further information:
http://www.mpip-mainz.mpg.de/eu-projekte/bacteriosafe/
http://www.mpip-mainz.mpg.de/eu-projekte/embek1/

More articles from Materials Sciences:

nachricht Move over, Superman! NIST method sees through concrete to detect early-stage corrosion
27.04.2017 | National Institute of Standards and Technology (NIST)

nachricht Control of molecular motion by metal-plated 3-D printed plastic pieces
27.04.2017 | Ecole Polytechnique Fédérale de Lausanne

All articles from Materials Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Making lightweight construction suitable for series production

More and more automobile companies are focusing on body parts made of carbon fiber reinforced plastics (CFRP). However, manufacturing and repair costs must be further reduced in order to make CFRP more economical in use. Together with the Volkswagen AG and five other partners in the project HolQueSt 3D, the Laser Zentrum Hannover e.V. (LZH) has developed laser processes for the automatic trimming, drilling and repair of three-dimensional components.

Automated manufacturing processes are the basis for ultimately establishing the series production of CFRP components. In the project HolQueSt 3D, the LZH has...

Im Focus: Wonder material? Novel nanotube structure strengthens thin films for flexible electronics

Reflecting the structure of composites found in nature and the ancient world, researchers at the University of Illinois at Urbana-Champaign have synthesized thin carbon nanotube (CNT) textiles that exhibit both high electrical conductivity and a level of toughness that is about fifty times higher than copper films, currently used in electronics.

"The structural robustness of thin metal films has significant importance for the reliable operation of smart skin and flexible electronics including...

Im Focus: Deep inside Galaxy M87

The nearby, giant radio galaxy M87 hosts a supermassive black hole (BH) and is well-known for its bright jet dominating the spectrum over ten orders of magnitude in frequency. Due to its proximity, jet prominence, and the large black hole mass, M87 is the best laboratory for investigating the formation, acceleration, and collimation of relativistic jets. A research team led by Silke Britzen from the Max Planck Institute for Radio Astronomy in Bonn, Germany, has found strong indication for turbulent processes connecting the accretion disk and the jet of that galaxy providing insights into the longstanding problem of the origin of astrophysical jets.

Supermassive black holes form some of the most enigmatic phenomena in astrophysics. Their enormous energy output is supposed to be generated by the...

Im Focus: A Quantum Low Pass for Photons

Physicists in Garching observe novel quantum effect that limits the number of emitted photons.

The probability to find a certain number of photons inside a laser pulse usually corresponds to a classical distribution of independent events, the so-called...

Im Focus: Microprocessors based on a layer of just three atoms

Microprocessors based on atomically thin materials hold the promise of the evolution of traditional processors as well as new applications in the field of flexible electronics. Now, a TU Wien research team led by Thomas Müller has made a breakthrough in this field as part of an ongoing research project.

Two-dimensional materials, or 2D materials for short, are extremely versatile, although – or often more precisely because – they are made up of just one or a...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Expert meeting “Health Business Connect” will connect international medical technology companies

20.04.2017 | Event News

Wenn der Computer das Gehirn austrickst

18.04.2017 | Event News

7th International Conference on Crystalline Silicon Photovoltaics in Freiburg on April 3-5, 2017

03.04.2017 | Event News

 
Latest News

Bare bones: Making bones transparent

27.04.2017 | Life Sciences

Study offers new theoretical approach to describing non-equilibrium phase transitions

27.04.2017 | Physics and Astronomy

From volcano's slope, NASA instrument looks sky high and to the future

27.04.2017 | Earth Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>