Tamoxifen alone may adequately control breast cancer, avoiding side effects
Older women treated with tamoxifen after removal of early-stage breast cancer by lumpectomy may safely be able to avoid radiation therapy and its unpleasant side effects. In the Sept. 2 New England Journal of Medicine, investigators from several major cancer research groups report that adding radiation to post-surgical tamoxifen treatment of women age 70 or older does not improve survival, has minimal impact on the risk of local tumor recurrence and does not prevent the need for eventual mastectomy. “If a patient does not need to have radiation therapy, her quality of life can improve significantly,” says Kevin Hughes, MD, of the Massachusetts General Hospital (MGH) Cancer Center, who led the study. “By showing that radiation therapy has very little impact on outcome for these patients, we can help each woman and her physician decide on the right treatment.”
Many breast cancers depend on the hormone estrogen to grow. So tamoxifen, which blocks the interaction between estrogen and its receptor protein, is used to treatment tumors that have that protein on the surface of their cells. Most older breast cancer patients have receptor-positive tumors and receive tamoxifen, a medication that has few side effects.
Sue McGreevey | EurekAlert!
Gelatine instead of forearm
19.04.2017 | Empa - Eidgenössische Materialprüfungs- und Forschungsanstalt
Computers create recipe for two new magnetic materials
18.04.2017 | Duke University
The nearby, giant radio galaxy M87 hosts a supermassive black hole (BH) and is well-known for its bright jet dominating the spectrum over ten orders of magnitude in frequency. Due to its proximity, jet prominence, and the large black hole mass, M87 is the best laboratory for investigating the formation, acceleration, and collimation of relativistic jets. A research team led by Silke Britzen from the Max Planck Institute for Radio Astronomy in Bonn, Germany, has found strong indication for turbulent processes connecting the accretion disk and the jet of that galaxy providing insights into the longstanding problem of the origin of astrophysical jets.
Supermassive black holes form some of the most enigmatic phenomena in astrophysics. Their enormous energy output is supposed to be generated by the...
The probability to find a certain number of photons inside a laser pulse usually corresponds to a classical distribution of independent events, the so-called...
Microprocessors based on atomically thin materials hold the promise of the evolution of traditional processors as well as new applications in the field of flexible electronics. Now, a TU Wien research team led by Thomas Müller has made a breakthrough in this field as part of an ongoing research project.
Two-dimensional materials, or 2D materials for short, are extremely versatile, although – or often more precisely because – they are made up of just one or a...
Two researchers at Heidelberg University have developed a model system that enables a better understanding of the processes in a quantum-physical experiment...
Glaciers might seem rather inhospitable environments. However, they are home to a diverse and vibrant microbial community. It’s becoming increasingly clear that they play a bigger role in the carbon cycle than previously thought.
A new study, now published in the journal Nature Geoscience, shows how microbial communities in melting glaciers contribute to the Earth’s carbon cycle, a...
20.04.2017 | Event News
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21.04.2017 | Physics and Astronomy
21.04.2017 | Health and Medicine
21.04.2017 | Physics and Astronomy