Material scientists from Bremen (Germany) and Stanford have identified nanodiamonds as potent bactericidal agent and published an article in „ACS Nano“.
Exhibiting a diameter of 5 nanometers, nanodiamonds are 200-times smaller than a bacterium. Nanodiamonds are produced by the explosion of carbon-containing compounds in high-pressure storage tanks. Here, the tiny detonation diamonds are formed besides large amounts of soot.
The colored particles display different types of nanodiamonds that bind to bacterial cells (grey) and kill them.
The material scientists Dr. Michael Maas, Julia Wehling and Professor Kurosch Rezwan from the University of Bremen (Germany) have now identified the strong antibacterial properties of these nanodiamonds. Besides silver and copper, nanodiamonds might be used as a new effective agent against bacterial contaminations and infections.
Discovered in the 1960s by Russian scientists, nanodiamonds only recently came into the spotlight, caused by current breakthroughs in processing and pretreatments that enabled their use in laboratories. Heat treatment of the grayish brown diamond powder can be used to generate different chemical groups on the nanodiamond surface. Biologist Julia Wehling and chemist and project leader Dr. Michael Maas discovered that some types of nanodiamonds kill bacterial cells rapidly and efficiently.
Seeking to understand the reason for the antibacterial properties, both material scientists from the Advanced Ceramics Group of Prof. Dr.-Ing. Kurosch Rezwan puzzled out the cause: some oxygen-containing groups on the surface of nanodiamonds, such as acid anhydrides, seem to be responsible for the antibacterial effect of the diamonds.
“The discovery that nanodiamonds kill bacterial cells as effectively as silver, which has been already used for 7000 years, opens a multitude of possible applications in biomedicine and material science. Furthermore, the concentrations that we used are proven to be nontoxic for human cells.
This enables the use of nanodiamonds for surface coatings or as additives for disinfectants. In the era of antibiotic resistances, the discovery of a new antibacterial material can be seen as a breakthrough”, says Julia Wehling.
The only scarcely explored diamonds were brought to the attention of Dr. Michael Maas by Prof. Richard N. Zare during a visit at Stanford University in California. “After my return, we directly started using nanodiamonds in the different nanosystems that we are working with in Bremen.
We were quite surprised by how efficiently nanodiamonds killed bacteria and we are convinced that our discovery will be of great impact for further research. It can be expected that nanodiamonds will play a key role in different areas dealing with bacterial infection. Our next goal is to equip implant materials with nanodiamonds to provide them with antibacterial properties. At the same time, we want to further analyze the diamond surface”, Michael Maas says.
Professor Kurosch Rezwan, director of the Advanced Ceramics department at the University of Bremen also sees great potential in the antibacterial nanodiamonds and points out that the publication in the renowned journal “ACS Nano” would not have been possible without the excellent collaboration with Prof. Dr. Ralf Dringen as the leader of the Biomolecular Interactions and Neurobiochemistry Group of the University of Bremen and Prof. Richard N. Zare of the department of chemistry of the Stanford University.
Julia Wehling, Ralf Dringen, Richard N. Zare, Michael Maas, Kurosch Rezwan: Bactericidal Activity of Partially Oxidized Nanodiamonds, ACS Nano, 2014, http://pubs.acs.org/doi/abs/10.1021/nn502230m.
Keramische Werkstoffe und Bauteile / Advanced Ceramics
M.Sc. Julia Wehling
Tel.: +49 421 218 64966
Dr. rer. nat. Michael Maas
Tel.: +49 421 218 64939
Prof. Dr.-Ing. Kurosch Rezwan
Tel.: +49 421 218 64930
Eberhard Scholz | idw - Informationsdienst Wissenschaft
How effective are bonding agents? Fraunhofer uses liquid chromatography for characterization
24.10.2017 | Fraunhofer-Institut für Betriebsfestigkeit und Systemzuverlässigkeit LBF
Flying: Efficiency thanks to Lightweight Air Nozzles
23.10.2017 | Technische Universität Chemnitz
Salmonellae are dangerous pathogens that enter the body via contaminated food and can cause severe infections. But these bacteria are also known to target...
University of Maryland researchers contribute to historic detection of gravitational waves and light created by event
On August 17, 2017, at 12:41:04 UTC, scientists made the first direct observation of a merger between two neutron stars--the dense, collapsed cores that remain...
Seven new papers describe the first-ever detection of light from a gravitational wave source. The event, caused by two neutron stars colliding and merging together, was dubbed GW170817 because it sent ripples through space-time that reached Earth on 2017 August 17. Around the world, hundreds of excited astronomers mobilized quickly and were able to observe the event using numerous telescopes, providing a wealth of new data.
Previous detections of gravitational waves have all involved the merger of two black holes, a feat that won the 2017 Nobel Prize in Physics earlier this month....
Material defects in end products can quickly result in failures in many areas of industry, and have a massive impact on the safe use of their products. This is why, in the field of quality assurance, intelligent, nondestructive sensor systems play a key role. They allow testing components and parts in a rapid and cost-efficient manner without destroying the actual product or changing its surface. Experts from the Fraunhofer IZFP in Saarbrücken will be presenting two exhibits at the Blechexpo in Stuttgart from 7–10 November 2017 that allow fast, reliable, and automated characterization of materials and detection of defects (Hall 5, Booth 5306).
When quality testing uses time-consuming destructive test methods, it can result in enormous costs due to damaging or destroying the products. And given that...
Using a new cooling technique MPQ scientists succeed at observing collisions in a dense beam of cold and slow dipolar molecules.
How do chemical reactions proceed at extremely low temperatures? The answer requires the investigation of molecular samples that are cold, dense, and slow at...
23.10.2017 | Event News
17.10.2017 | Event News
10.10.2017 | Event News
24.10.2017 | Physics and Astronomy
24.10.2017 | Physics and Astronomy
24.10.2017 | Life Sciences