Material scientists from Bremen (Germany) and Stanford have identified nanodiamonds as potent bactericidal agent and published an article in „ACS Nano“.
Exhibiting a diameter of 5 nanometers, nanodiamonds are 200-times smaller than a bacterium. Nanodiamonds are produced by the explosion of carbon-containing compounds in high-pressure storage tanks. Here, the tiny detonation diamonds are formed besides large amounts of soot.
The colored particles display different types of nanodiamonds that bind to bacterial cells (grey) and kill them.
The material scientists Dr. Michael Maas, Julia Wehling and Professor Kurosch Rezwan from the University of Bremen (Germany) have now identified the strong antibacterial properties of these nanodiamonds. Besides silver and copper, nanodiamonds might be used as a new effective agent against bacterial contaminations and infections.
Discovered in the 1960s by Russian scientists, nanodiamonds only recently came into the spotlight, caused by current breakthroughs in processing and pretreatments that enabled their use in laboratories. Heat treatment of the grayish brown diamond powder can be used to generate different chemical groups on the nanodiamond surface. Biologist Julia Wehling and chemist and project leader Dr. Michael Maas discovered that some types of nanodiamonds kill bacterial cells rapidly and efficiently.
Seeking to understand the reason for the antibacterial properties, both material scientists from the Advanced Ceramics Group of Prof. Dr.-Ing. Kurosch Rezwan puzzled out the cause: some oxygen-containing groups on the surface of nanodiamonds, such as acid anhydrides, seem to be responsible for the antibacterial effect of the diamonds.
“The discovery that nanodiamonds kill bacterial cells as effectively as silver, which has been already used for 7000 years, opens a multitude of possible applications in biomedicine and material science. Furthermore, the concentrations that we used are proven to be nontoxic for human cells.
This enables the use of nanodiamonds for surface coatings or as additives for disinfectants. In the era of antibiotic resistances, the discovery of a new antibacterial material can be seen as a breakthrough”, says Julia Wehling.
The only scarcely explored diamonds were brought to the attention of Dr. Michael Maas by Prof. Richard N. Zare during a visit at Stanford University in California. “After my return, we directly started using nanodiamonds in the different nanosystems that we are working with in Bremen.
We were quite surprised by how efficiently nanodiamonds killed bacteria and we are convinced that our discovery will be of great impact for further research. It can be expected that nanodiamonds will play a key role in different areas dealing with bacterial infection. Our next goal is to equip implant materials with nanodiamonds to provide them with antibacterial properties. At the same time, we want to further analyze the diamond surface”, Michael Maas says.
Professor Kurosch Rezwan, director of the Advanced Ceramics department at the University of Bremen also sees great potential in the antibacterial nanodiamonds and points out that the publication in the renowned journal “ACS Nano” would not have been possible without the excellent collaboration with Prof. Dr. Ralf Dringen as the leader of the Biomolecular Interactions and Neurobiochemistry Group of the University of Bremen and Prof. Richard N. Zare of the department of chemistry of the Stanford University.
Julia Wehling, Ralf Dringen, Richard N. Zare, Michael Maas, Kurosch Rezwan: Bactericidal Activity of Partially Oxidized Nanodiamonds, ACS Nano, 2014, http://pubs.acs.org/doi/abs/10.1021/nn502230m.
Keramische Werkstoffe und Bauteile / Advanced Ceramics
M.Sc. Julia Wehling
Tel.: +49 421 218 64966
Dr. rer. nat. Michael Maas
Tel.: +49 421 218 64939
Prof. Dr.-Ing. Kurosch Rezwan
Tel.: +49 421 218 64930
Eberhard Scholz | idw - Informationsdienst Wissenschaft
Superconductivity research reveals potential new state of matter
17.08.2017 | DOE/Los Alamos National Laboratory
Spray-on electric rainbows: Making safer electrochromic inks
17.08.2017 | Georgia Institute of Technology
Whether you call it effervescent, fizzy, or sparkling, carbonated water is making a comeback as a beverage. Aside from quenching thirst, researchers at the University of Illinois at Urbana-Champaign have discovered a new use for these "bubbly" concoctions that will have major impact on the manufacturer of the world's thinnest, flattest, and one most useful materials -- graphene.
As graphene's popularity grows as an advanced "wonder" material, the speed and quality at which it can be manufactured will be paramount. With that in mind,...
Physicists at the University of Bonn have managed to create optical hollows and more complex patterns into which the light of a Bose-Einstein condensate flows. The creation of such highly low-loss structures for light is a prerequisite for complex light circuits, such as for quantum information processing for a new generation of computers. The researchers are now presenting their results in the journal Nature Photonics.
Light particles (photons) occur as tiny, indivisible portions. Many thousands of these light portions can be merged to form a single super-photon if they are...
For the first time, scientists have shown that circular RNA is linked to brain function. When a RNA molecule called Cdr1as was deleted from the genome of mice, the animals had problems filtering out unnecessary information – like patients suffering from neuropsychiatric disorders.
While hundreds of circular RNAs (circRNAs) are abundant in mammalian brains, one big question has remained unanswered: What are they actually good for? In the...
An experimental small satellite has successfully collected and delivered data on a key measurement for predicting changes in Earth's climate.
The Radiometer Assessment using Vertically Aligned Nanotubes (RAVAN) CubeSat was launched into low-Earth orbit on Nov. 11, 2016, in order to test new...
A study led by scientists of the Max Planck Institute for the Structure and Dynamics of Matter (MPSD) at the Center for Free-Electron Laser Science in Hamburg presents evidence of the coexistence of superconductivity and “charge-density-waves” in compounds of the poorly-studied family of bismuthates. This observation opens up new perspectives for a deeper understanding of the phenomenon of high-temperature superconductivity, a topic which is at the core of condensed matter research since more than 30 years. The paper by Nicoletti et al has been published in the PNAS.
Since the beginning of the 20th century, superconductivity had been observed in some metals at temperatures only a few degrees above the absolute zero (minus...
16.08.2017 | Event News
04.08.2017 | Event News
26.07.2017 | Event News
17.08.2017 | Physics and Astronomy
17.08.2017 | Earth Sciences
17.08.2017 | Physics and Astronomy