Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Gold Nanoparticle Catalyst that Learns from Enzyme in Nature

16.11.2012
A team led by Dr. Kazushi Miki, Group Leader of the Functional Heterointerface Group, Polymer Materials Unit, National Institute for Materials Science succeeded in development of a high activity gold nanoparticle catalyst that simplify the function of enzyme in capturing substances.
A team led by Dr. Kazushi Miki, Group Leader of the Functional Heterointerface Group, Polymer Materials Unit (Unit Director: Izumi Ichinose), National Institute for Materials Science (President: Sukekatsu Ushioda) succeeded in development of a high activity gold nanoparticle catalyst that simplify the function of enzyme in capturing substances.

This new type of catalyst mimics enzyme, which supports biological activities as a catalyst in the reactions of the living body. Metalloenzymes has metal element which functions as a catalyst in the active center, and manifest extremely high activity and selectivity by possessing a function in which proteins surrounding the vicinity capture designated substances at activity sites. The NIMS group succeeded in realizing catalytic activity similar to that of metalloenzymes by simplifying the structure of these metalloenzymes in gold nanoparticles coated with alkanethiol molecules.

In this work, the NIMS research group focused on the fact that a self-assembled alkanethiol monolayer formed on the surface of gold nanoparticles (AuNP) possesses an interaction similar to that of cell membranes (lipid bilayer), which capture molecules of designated lengths and shapes. Because the molecules which are captured on the particle surface by this interaction increase the probability of contact with the gold particle surface, which has a catalytic function, the catalytic reaction is accelerated. Concretely, a high activity catalytic reaction was discovered, in which silane molecules are efficiently activated on the surface of gold, which is a catalyst, by capture of silane molecules and alcohol molecules on the surface of the gold particles.

As this result confirmed the mechanism of a catalytic reaction similar to that of metalloenzymes, it is expected to be possible to realize catalysts with a combination of high activity and high selectivity by designing modified molecules for AuNP. Furthermore, unlike natural enzyme, which can only be used stable in aqueous solutions, AuNP display extremely high chemical stability, enabling use under acidic and basic solution conditions and in organic solvents. Thus, there are no restrictions on industrial use.

This research was carried out as part of the research subject “Spatial and Temporal Integration of Near Field Reinforced Photochemical Reactions” (FY 2010-2012; Research Representative: Kazushi Miki) in the Ministry of Education, Culture, Sports, Science and Technology (MEXT) Grants in Aid for Scientific Research on Innovative Areas research field “Organic Synthesis Based on Reaction Integration: Development of New Methods and Creation of New Substances” (Area Representative: Jun-ichi Yoshida, Professor, Kyoto University Graduate School of Engineering;

Fig : Schematic diagram of the new catalyst (a) The new catalyst has a structure in which gold nanoparticles (AuNP) having a size of 10nm (1/100 millionth of 1m) coated with alkanethiol are regularly arranged on a flat substrate. (b) In this scanning electron microscope image, it can be understood that the actual size of the AuNP is 9.0nm, and the gap between the AuNP is 2.4nm.

http://www.sbchem.kyoto-u.ac.jp/syuuseki/index ).

A patent application has already been filed in connection with this research.

These results will soon be published in the journal of Advanced Materials (Wiley).

Mikiko Tanifuji | Research asia research news
Further information:
http://www.nims.go.jp/eng/
http://www.researchsea.com

More articles from Materials Sciences:

nachricht Engineers develop smart material that changes stiffness when twisted or bent
15.02.2018 | Iowa State University

nachricht Breaking local symmetry: Why water freezes but silica forms a glass
14.02.2018 | Institute of Industrial Science, The University of Tokyo

All articles from Materials Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Demonstration of a single molecule piezoelectric effect

Breakthrough provides a new concept of the design of molecular motors, sensors and electricity generators at nanoscale

Researchers from the Institute of Organic Chemistry and Biochemistry of the CAS (IOCB Prague), Institute of Physics of the CAS (IP CAS) and Palacký University...

Im Focus: Hybrid optics bring color imaging using ultrathin metalenses into focus

For photographers and scientists, lenses are lifesavers. They reflect and refract light, making possible the imaging systems that drive discovery through the microscope and preserve history through cameras.

But today's glass-based lenses are bulky and resist miniaturization. Next-generation technologies, such as ultrathin cameras or tiny microscopes, require...

Im Focus: Stem cell divisions in the adult brain seen for the first time

Scientists from the University of Zurich have succeeded for the first time in tracking individual stem cells and their neuronal progeny over months within the intact adult brain. This study sheds light on how new neurons are produced throughout life.

The generation of new nerve cells was once thought to taper off at the end of embryonic development. However, recent research has shown that the adult brain...

Im Focus: Interference as a new method for cooling quantum devices

Theoretical physicists propose to use negative interference to control heat flow in quantum devices. Study published in Physical Review Letters

Quantum computer parts are sensitive and need to be cooled to very low temperatures. Their tiny size makes them particularly susceptible to a temperature...

Im Focus: Autonomous 3D scanner supports individual manufacturing processes

Let’s say the armrest is broken in your vintage car. As things stand, you would need a lot of luck and persistence to find the right spare part. But in the world of Industrie 4.0 and production with batch sizes of one, you can simply scan the armrest and print it out. This is made possible by the first ever 3D scanner capable of working autonomously and in real time. The autonomous scanning system will be on display at the Hannover Messe Preview on February 6 and at the Hannover Messe proper from April 23 to 27, 2018 (Hall 6, Booth A30).

Part of the charm of vintage cars is that they stopped making them long ago, so it is special when you do see one out on the roads. If something breaks or...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

2nd International Conference on High Temperature Shape Memory Alloys (HTSMAs)

15.02.2018 | Event News

Aachen DC Grid Summit 2018

13.02.2018 | Event News

How Global Climate Policy Can Learn from the Energy Transition

12.02.2018 | Event News

 
Latest News

Fingerprints of quantum entanglement

16.02.2018 | Information Technology

'Living bandages': NUST MISIS scientists develop biocompatible anti-burn nanofibers

16.02.2018 | Health and Medicine

Hubble sees Neptune's mysterious shrinking storm

16.02.2018 | Physics and Astronomy

VideoLinks
Science & Research
Overview of more VideoLinks >>>