Electronics manufacturers constantly hunt for ways to make faster, cheaper computer chips, often by cutting production costs or by shrinking component sizes. Now, researchers report that DNA, the genetic material of life, might help accomplish this goal when it is formed into specific shapes through a process reminiscent of the ancient art of paper folding.
The researchers present their work today at the 251st National Meeting & Exposition of the American Chemical Society (ACS). ACS, the world's largest scientific society, is holding the meeting here through Thursday. It features more than 12,500 presentations on a wide range of science topics.
"We would like to use DNA's very small size, base-pairing capabilities and ability to self-assemble, and direct it to make nanoscale structures that could be used for electronics," Adam T. Woolley, Ph.D., says. He explains that the smallest features on chips currently produced by electronics manufacturers are 14 nanometers wide. That's more than 10 times larger than the diameter of single-stranded DNA, meaning that this genetic material could form the basis for smaller-scale chips.
"The problem, however, is that DNA does not conduct electricity very well," he says. "So we use the DNA as a scaffold and then assemble other materials on the DNA to form electronics."
To design computer chips similar in function to those that Silicon Valley churns out, Woolley, in collaboration with Robert C. Davis, Ph.D., and John N. Harb, Ph.D., at Brigham Young University, is building on other groups' prior work on DNA origami and DNA nanofabrication.
The most familiar form of DNA is a double helix, which consists of two single strands of DNA. Complementary bases on each strand pair up to connect the two strands, much like rungs on a twisted ladder. But to create a DNA origami structure, researchers begin with a long single strand of DNA. The strand is flexible and floppy, somewhat like a shoelace. Scientists then mix it with many other short strands of DNA -- known as "staples" -- that use base pairing to pull together and crosslink multiple, specific segments of the long strand to form a desired shape.
However, Woolley's team isn't content with merely replicating the flat shapes typically used in traditional two-dimensional circuits. "With two dimensions, you are limited in the density of components you can place on a chip," Woolley explains. "If you can access the third dimension, you can pack in a lot more components."
Kenneth Lee, an undergraduate who works with Woolley, has built a 3-D, tube-shaped DNA origami structure that sticks up like a smokestack from substrates, such as silicon, that will form the bottom layer of their chip. Lee has been experimenting with attaching additional short strands of DNA to fasten other components such as nano-sized gold particles at specific sites on the inside of the tube.
The researchers' ultimate goal is to place such tubes, and other DNA origami structures, at particular sites on the substrate. The team would also link the structures' gold nanoparticles with semiconductor nanowires to form a circuit. In essence, the DNA structures serve as girders on which to build an integrated circuit.
Lee is currently testing the characteristics of the tubular DNA. He plans to attach additional components inside the tube, with the eventual aim of forming a semiconductor.
Woolley notes that a conventional chip fabrication facility costs more than $1 billion, in part because the equipment necessary to achieve the minuscule dimensions of chip components is expensive and because the multi-step manufacturing process requires hundreds of instruments. In contrast, a facility that harnesses DNA's knack for self-assembly would likely entail much lower start-up funding, he states. "Nature works on a large scale, and it is really good at assembling things reliably and efficiently," he says. "If that could be applied in making circuits for computers, there's potential for huge cost savings."
A press conference on this topic will be held Monday, March 14, at 1 p.m. Pacific time in the San Diego Convention Center. Reporters may check-in at Room 16B (Mezzanine) in person, or watch live on YouTube http://bit.
The researchers acknowledge funding from the Semiconductor Research Corporation.
The American Chemical Society is a nonprofit organization chartered by the U.S. Congress. With more than 158,000 members, ACS is the world's largest scientific society and a global leader in providing access to chemistry-related research through its multiple databases, peer-reviewed journals and scientific conferences. Its main offices are in Washington, D.C., and Columbus, Ohio.
To automatically receive news releases from the American Chemical Society, contact email@example.com.
Note to journalists: Please report that this research is being presented at a meeting of the American Chemical Society.
3D DNA Origami Templated Nanoscale Device Fabrication
Because electronic and mechanical devices continue to decrease in size, exploring nontraditional fabrication methods provides added opportunities. For example, materials not currently used in devices, such as biological molecules, can contribute to new fabrication procedures. Self-assembling biological molecules especially show promise as useful starting materials, because nanodevice fabrication can exploit interactions that lead to highly specific self-assembly. DNA origami is a method that folds pieces of single-stranded DNA into designed structures by taking advantage of nucleotide base-pairing. Designs that include single-stranded extensions can provide further attachment points for other materials such as metal nanoparticles and nanorods. Such specific placement of metal on a DNA origami template can create nanowires as part of a larger nanocircuit. 2-D DNA origami templates can help position materials in a planar circuit pattern, but 3-D DNA origami uses a third dimension to further compact the nanocircuit elements. To test possible applications of 3-D origami, I designed a tube-shaped DNA origami with a hollow center. To verify correct folding of DNA origami structures, I stained them with lanthanum (III) and lead (II) and imaged them with SEM. I also made two variations of the tube-shaped origami, one with a location for nanoparticle attachment at an end of the tube and one with a location for particle attachment in the center of the tube. To verify successful attachment of gold nanoparticles, I confirmed with SEM imaging the presence of origami-nanoparticle hybrids. This design provides several possibilities for attachment of nanomaterials, both inside the hollow center and to the outside of the tube, which provide a pathway to creating a vertical nanowire logic gate. A flat base-like DNA origami could then position an array of tube DNA origami structures for more complex applications. An array of this type could be a step towards making more compact electronics.
Michael Bernstein | EurekAlert!
Spin current detection in quantum materials unlocks potential for alternative electronics
16.10.2017 | DOE/Oak Ridge National Laboratory
Missing atoms in a forgotten crystal bring luminescence
11.10.2017 | King Abdullah University of Science & Technology (KAUST)
Material defects in end products can quickly result in failures in many areas of industry, and have a massive impact on the safe use of their products. This is why, in the field of quality assurance, intelligent, nondestructive sensor systems play a key role. They allow testing components and parts in a rapid and cost-efficient manner without destroying the actual product or changing its surface. Experts from the Fraunhofer IZFP in Saarbrücken will be presenting two exhibits at the Blechexpo in Stuttgart from 7–10 November 2017 that allow fast, reliable, and automated characterization of materials and detection of defects (Hall 5, Booth 5306).
When quality testing uses time-consuming destructive test methods, it can result in enormous costs due to damaging or destroying the products. And given that...
Using a new cooling technique MPQ scientists succeed at observing collisions in a dense beam of cold and slow dipolar molecules.
How do chemical reactions proceed at extremely low temperatures? The answer requires the investigation of molecular samples that are cold, dense, and slow at...
Scientists from the Max Planck Institute of Quantum Optics, using high precision laser spectroscopy of atomic hydrogen, confirm the surprisingly small value of the proton radius determined from muonic hydrogen.
It was one of the breakthroughs of the year 2010: Laser spectroscopy of muonic hydrogen resulted in a value for the proton charge radius that was significantly...
It's possible to produce hydrogen to power fuel cells by extracting the gas from seawater, but the electricity required to do it makes the process costly. UCF...
Mercury, our smallest planetary neighbor, has very little to call an atmosphere, but it does have a strange weather pattern: morning micro-meteor showers.
Recent modeling along with previously published results from NASA's MESSENGER spacecraft -- short for Mercury Surface, Space Environment, Geochemistry and...
10.10.2017 | Event News
10.10.2017 | Event News
28.09.2017 | Event News
16.10.2017 | Physics and Astronomy
16.10.2017 | Earth Sciences
16.10.2017 | Physics and Astronomy